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All Journal Indonesian Journal of Kidney and Hypertension PREPOTIF : Jurnal Kesehatan Masyarakat
Trisnawati, Ni Nyoman Ayu
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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HIPOKALSEMIA PASCA TIROIDEKTOMI : LAPORAN KASUS Trisnawati, Ni Nyoman Ayu; Dwipayana, I Made Pande
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 10 No. 1 (2026): APRIL 2026
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v10i1.54820

Abstract

Hipokalsemia merupakan suatu gangguan biokimia yang dapat bersifat asimtomatik pada kasus ringan atau muncul sebagai kondisi akut yang mengancam jiwa. Kadar kalsium dalam tubuh diatur oleh hormon paratiroid (parathyroid hormone/PTH), vitamin D, dan kalsitonin melalui efek spesifik pada saluran cerna, ginjal, dan tulang. Kami melaporkan sebuah kasus hipokalsemia pasca-tiroidektomi pada seorang perempuan berusia 62 tahun. Pasien datang dengan keluhan rasa kaku pada mulut, tangan, dan kaki. Pemeriksaan fisik menunjukkan tanda Chvostek positif, interval QT memanjang pada elektrokardiografi, serta hipokalsemia pada pemeriksaan laboratorium. Gejala klinis membaik setelah empat hari pemberian terapi kalsium dan kalsitriol. Namun, hipokalsemia akibat hipoparatiroidisme primer memiliki kecenderungan untuk kambuh. Oleh karena itu, diperlukan pemberian rutin kalsium oral dan kalsitriol oral sebagai terapi jangka panjang. Pemantauan laboratorium juga perlu dilakukan secara berkala, setidaknya setiap 3–6 bulan. Ke depan, terapi pengganti menggunakan PTH rekombinan dapat menjadi alternatif pengobatan pada kasus hipokalsemia pasca-tiroidektomi.
Seroprevalence of CMV and HSV in Kidney Transplant Donor Candidates and Recipients at Ngoerah Hospital, Denpasar Trisnawati, Ni Nyoman Ayu; Somia, I Ketut Agus; Kandarini, Yenny
Indonesian Journal of Kidney and Hypertension Vol 3 No 1 (2026): Vol 3 No 1 (2026): Volume 3 No. 1, April 2026
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

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Abstract

Background: Despite significant advancements in solid organ transplantation over recent decades, infections remain a leading cause of morbidity and mortality among transplant recipients. Herpesviruses, particularly Cytomegalovirus (CMV) and Herpes Simplex Virus (HSV), are the most common viral pathogens affecting this patient population. This study aims to evaluate the seroprevalence of CMV and HSV infections among kidney transplant donor and recipient candidates at RS. Ngoerah Denpasar. Methods: This descriptive study involved 66 adult subjects, comprising 33 kidney transplant donor candidates and 33 recipient candidates, all aged over 18 years. The study participants were evaluated for CMV and HSV seroprevalence using serological tests, including IgG and IgM antibodies, to determine the presence of latent or active infections. The study population included patients with chronic kidney disease (CKD) stage V who were candidates for kidney transplantation. Results: Among the 33 donor candidates, 39.4% were found to have both CMV and HSV infections, with 45.5% testing positive for IgG anti-CMV, indicating a latent CMV infection. In the recipient candidate group, 27.3% were infected with both CMV and HSV, with 42.4% showing seropositivity for IgG anti-CMV. Additionally, a small proportion of donor and recipient candidates were found to have reactivated HSV infections, as indicated by the presence of IgM antibodies. The study highlights the significant prevalence of CMV and HSV infections among kidney transplant donor and recipient candidates. Conclusion: These findings underscore the importance of thorough serological screening prior to transplantation to identify latent infections that may influence post-transplant outcomes.
Co-Authors I Ketut Agus Somia I Made Pande Dwipayana Putra, I Made Suwija Sudana, A.A. Kompiang Oka Yenny Kandarini