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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Journal of International Surgery and Clinical Medicine
Yanis, Melissa Abigail
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Physics

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Pain score evaluation in patients underwent hand surgery under WALANT compared to those under local or general anesthesia with tourniquet Teuku Nanda Putra; Yanis, Melissa Abigail
Journal of International Surgery and Clinical Medicine Vol. 3 No. 2 (2023): (Available online: December 2023)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v3i2.38

Abstract

Background: The Wide Awake Local Anesthesia No Tourniquet (WALANT) has been reported to offer simpler pre-surgical instruction and assessment, faster operating time, better surgical visualization, shorter hospital stay, fewer complications and side effects, lower cost, faster post-operative recovery time, better patient’s satisfaction, and less pain and discomfort. This study aims to review the pain score in hand surgery using the WALANT technique compared to local anesthesia or general anesthesia with a tourniquet. Methods: A comprehensive literature search was conducted in PubMed, Cochrane Library, and Google Scholar in March 2021. Eligible randomized-controlled trials (RCTs) and cohort studies compared injection time intra-operative or post-operative pain using Visual Analog Score (VAS) in WALANT and local anesthesia or general anesthesia with a tourniquet. Results: Five studies (3 RCTs and two cohorts) were included in this article, including 645 hand surgeries (376 carpal tunnel syndrome cases, 181 trigger finger cases, 42 cubital tunnel syndrome cases, 44 de Quervain’s disease cases, and two ganglion cyst cases). Three studies reported a significantly lower VAS in the WALANT group, while the other two reported a lower VAS in the WALANT group, but not statistically significant. Conclusion: WALANT is still a technique worth considering in hand surgery because of its superiority in minimizing intra-operative and post-operative pain.
Pain score evaluation in patient underwent hand surgery under walant compared to those under local or general anesthesia with tourniquet Teuku Nanda Putra; Yanis, Melissa Abigail
Journal of International Surgery and Clinical Medicine Vol. 4 No. 1 (2024): (Available online: 1 June 2024)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v4i1.53

Abstract

Background: The Wide Awake Local Anesthesia No Tourniquet (WALANT) has been reported to offer simpler pre-surgical instruction and assessment, faster operating time, better surgical visualization, shorter hospital stay, fewer complications, and side effects, lower cost, faster postoperative recovery time, better patient's satisfaction, and less pain and discomfort. This study aims to review the pain score in hand surgery using the WALANT technique compared to local anesthesia or general anesthesia with a tourniquet. Methods: A comprehensive literature search was conducted in PubMed, Cochrane Library, and Google Scholar in March 2021. Eligible randomized-controlled trials (RCTs) and cohort studies comparing injection time, intra-operative, or postoperative pain using Visual Analog Score (VAS) in WALANT and local anesthesia or general anesthesia with tourniquet were included. Results: Five studies (3 RCTs and 2 cohorts) were included in this article, including 645 hand surgeries (376 carpal tunnel syndrome cases, 181 trigger finger cases, 42 cubital tunnel syndrome cases, 44 de Quervain's disease cases, and 2 ganglion cyst cases). Three studies reported a significantly lower VAS in the WALANT group, while the other two studies reported a lower VAS in the WALANT group, but it was not statistically significant. Conclusion: WALANT is still a technique worth considering in hand surgery because of its superiority in minimizing intra-operative and postoperative pain.
Healing Potential of Chromolaena odorata Extract: Modulation of Neutrophil, Macrophage, and Lymphocyte Response in Infected Wounds of Mus musculus Yanis, Melissa Abigail; Amirsyah, Mirnasari; Harsono, Anastasia Dessy
Jurnal Penelitian Pendidikan IPA Vol 10 No 12 (2024): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i12.9423

Abstract

Chromolaena odorata has been reported to possess antimicrobial, antibacterial, and anti-inflammatory properties that aid in wound healing. Previous studies demonstrated the significant effects of a 7.5% concentration of C. odorata extract on non-infected wounds. This study aims to investigate its impact on infected wound healing. An experimental study was conducted on 36 mice, divided into two groups. Partial-thickness wounds were created on the dorsal side of each mouse and contaminated with S. aureus (106 CFU/ml). Group 1 was treated with normal saline, while Group 2 was treated with C. odorata aqueous extract at 7.5%. Histopathological analysis was performed on days 3 and 5 to count neutrophils, macrophages, and lymphocytes. Results showed a significantly lower neutrophil, macrophage, and lymphocyte count in Group 2 compared to Group 1 (p < 0.05). On day 3 and 5, Group 2 had lower neutrophil counts (5.6 ± 1.8, 5.8 ± 0.6) compared to Group 1 (9.2 ± 5.2, 15.1 ± 3.9). Macrophage counts were also lower in Group 2 (6.9 ± 1.7, 1.9 ± 0.7) compared to Group 1 (3.7 ± 1.4, 4.3 ± 0.9). Lymphocyte counts followed a similar trend, with Group 2 having fewer lymphocytes on both days (p < 0.05). In conclusion, C. odorata aqueous extract at a 7.5% concentration demonstrates potential as a wound healing agent by reducing inflammatory cells in infected wounds.
Co-Authors Amirsyah, Mirnasari Harsono, Anastasia Dessy Teuku Nanda Putra