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All Journal Pharmasipha Pharmacia
Erwina, Wiwi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Uji Aktivitas Antibakteri Perasan Jeruk Nipis (Citrus aurantifolia) terhadap Pertumbuhan Bakteri Propionibacterium acnes Frihendranus, Jeremia Eden; Sianturi, Sister; Erwina, Wiwi
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 6 No. 2 (2022): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v6i2.8597

Abstract

The main causes of skin infections is Propionibacterium acnes. The use of antibiotics can be an effective treatment of acne for example: clindamycin. Lime was a plant that is used as a treatment for acne’s inhibition. The lemon part often used to treat acne was the juice. The purpose of this study was to determine the activity of lime juice in inhibiting the growth of Propionibacterium acnes and to determine the minimum inhibitory concentration of lime juice against Propionibacterium acnes. The study used lime juice with various concentrations of 100%, 50%, 25%, and 12.5% on the growth of Propionibacterium acnes bacteria using the disc diffusion method. The data obtained were tested for normality Kolmogorov-Smirnov and homogeneity test. Then the Kruskall Wallis and Mann-Whiteney test were performed. Based on this study, lime juice was proven to be able to inhibit the growth of Propionibacterium acnes bacteria. The inhibition zone with the highest average concentration was at 100% concentration, which was 18.7 mm and the smallest average inhibition zone was found at a concentration of 12.5%, which was 11.5 mm. The results of the statistical test showed a significant difference with p-value= 0.029 between the positive control and the variation of the sample concentration.
STUDI KASUS METODE FIFO (First In First Out) DAN FEFO (First Expired First Out) PENGELOLAAN OBAT GENERIK TABLET DAN KAPSUL DALAM PENGGUNAAN BPJS KLINIK X BALIKPAPAN Hasanah, Nur; Retno, Eka Kumala; Erwina, Wiwi; Wardhana, Mada Aditia
PHARMACIA Vol. 2 No. 2 (2024): Pharmacy
Publisher : Program Studi Farmasi Universitas Mulia

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Abstract

Pengelolaan stok obat di fasilitas pelayanan kesehatan merupakan aspek krusial dalam menjamin keberlangsungan terapi pasien serta efisiensi penggunaan anggaran obat. Penggunaan metode FIFO (First In First Out) dan FEFO (First Expired First Out) merupakan strategi umum dalam manajemen persediaan obat. FIFO menekankan penggunaan stok yang pertama kali masuk, sementara FEFO memprioritaskan penggunaan obat yang memiliki tanggal kedaluwarsa paling dekat. Penelitian ini bertujuan untuk menganalisis penerapan kedua metode tersebut terhadap efektivitas dan efisiensi pengelolaan obat generik tablet dan kapsul di Klinik X Balikpapan dengan studi khusus pada dua jenis obat, yaitu cetirizine dan ranitidine. Pendekatan penelitian yang digunakan adalah kuantitatif deskriptif dengan teknik dokumentasi dan analisis data statistik. Hasil penelitian menunjukkan bahwa mayoritas batch berada pada kategori rata-rata dalam hal perputaran stok dan lama masa kedaluwarsa, meskipun ditemukan beberapa batch yang memiliki performa distribusi di bawah rata-rata. Hal ini menunjukkan perlunya penguatan sistem monitoring dan digitalisasi manajemen stok guna mendukung penerapan metode FIFO dan FEFO secara optimal.
Co-Authors Frihendranus, Jeremia Eden Mada Aditia Wardhana Nur Hasanah Retno, Eka Kumala Sister Sianturi