Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Chemical Studies (Indones. J. Chem. Stud.)
Hasanah, Rifdatul
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Arts Humanities Chemistry Education Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Spray Gel Formulation of Ethanolic Extract Senduduk Leaves (Melastoma malabatricum) Against Antioxidant Activity, SPF, and Chemical Components Analysis with LC-MS/MS Yulion, Rizky; Andriani, Lili; Asadi, Henityo Agung; 'Aliyah, Siti Hamidatul; Mariska, Ruri Putri; Perawati, Santi; Hasanah, Rifdatul
Indonesian Journal of Chemical Studies Vol. 2 No. 2 (2023): Indones. J. Chem. Stud., December 2023
Publisher : Indonesian Scholar Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55749/ijcs.v2i2.37

Abstract

Senduduk leave (Melastoma malabathricum) is one of the species in the melastomaceae family that has long been used by local Indonesian people, one of which is the Suku Anak Dalam (SAD) for various needs and also as traditional medicine. The study aimed to examine the antioxidant activity of ethanolic extract of senduduk leaves. The extract was then formulated into spray gel preparations as UV-B sunscreen. The research method used was starting from sampling, determination, making samples, soxhlet, determining the IC50 value, spray gel preparation formulation, formulation stability test, measuring sun protection factor (SPF) values, and identifying extract chemical components with the LC-MS/MS instrument. The results was that the ethanolic extract of senduduk leaves had an IC50 value of 49.73 μg/mL with the best SPF value at a concentration of 70 ppm, which is 19.98. Spray gel preparations with a concentration of 70 ppm have an IC50 value of 44.22 μg/mL, an SPF value of 24.96, and a potent antioxidant intensity. So, extract spray gel can potentially have activity as antioxidants and can be used as UV-B sunscreen. The compounds identified include quercetin, quercitrin, DEET, n-boc-3-pyrrolidinone, medicarpine, taxinine, and other compounds. The ethanol extract of the soxhlet results showed more promising results for further tests of in-vitro, in-vivo, and in-silico bioactivity studies.
PENYULUHAN DAN PEMERIKSAAN KESEHATAN KADAR KOLESTEROL DI DESA KOTO TENGAH, KECAMATAN DANAU KERINCI, KABUPATEN KERINCI Andriani, Medi; Haerul Afdal Mubarak, Mohd; Hasanah, Rifdatul; Wulandari, Aprilia; Putri Armellia, Sagita; Umil Hasanah.R, NR.; Fitrawati, Fitrawati; Sepriani, Sepriani
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 6, No 6 (2023): martabe : jurnal pengabdian kepada masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v6i6.2192-2196

Abstract

Kolesterol adalah lipid yang penting komponen dari hampir semua membran sel, serta prekursor berbagai hormon steroid seperti hormon seks (estrogen, testosteron, dan progesteron) dan kortikosteroid (kortikosteron, kortisol, kortison, dan aldosteron). Selain itu, sebagian besar kolesterol diubah menjadi asam empedu selama biosintesis empedu asam; langkah ini, bersama dengan bilier simultan sekresi kolesterol dan asam empedu menjadi empedu, berkurang konsentrasi kolesterol plasma dan membantu menghilangkan kelebihan kolesterol dari tubuh. Hiperkolesterolemia adalah kondisi umum yang ditandai dengan peningkatan kadar kolesterol lipoprotein densitas rendah (LDL-C) dan peningkatan risiko penyakit kardiovaskular aterosklerotik (ASCVD) penyakit degeneratif yang mempengaruhi metabolisme kolesterol darah dan mengakibatkan kadar kolesterol darah melebihi batas normal. plak, dan emboli. Kepatuhan diet dan pemberian obat sangat berperan penting dalam penurunan kadar kolestrol. Daun sirsak merupakan salah satu herbal anti kolesterol tinggi yang efektif. Tujuan dari penyuluhan ini agar warga dapat memahami serta memberikan informasi tentang kolesterol. Metode yang digunakan yaitu pemaparan materi tentang kolesterol dan pemeriksaan kesehatan kadar kolesterol sebagai bagian dari pengajian rutin oleh warga. Hasil yang didapatkan yaitu warga mengetahui bagaimana cara mencegah serta mengobati kolesterol.
Co-Authors 'Aliyah, Siti Hamidatul Andriani, Medi Fitrawati Fitrawati Haerul Afdal Mubarak, Mohd Lili Andriani M. Henityo Agung As'adi Putri Armellia, Sagita Rizky Yulion Ruri Putri Mariska Santi Perawati, Santi Sepriani, Sepriani Umil Hasanah.R, NR. WULANDARI, APRILIA