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All Journal Jurnal Kedokteran Brawijaya Pharmaceutical Sciences and Research (PSR)
Gunadi, Michael Sebastian
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Medicine & Pharmacology

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Antioxidant Activities of RoJa Herbal Tea: Combination of Rosella Flower (Hibiscus sabdariffa L.) and Ginger Rhizome (Zingiber officinale Rosc.) Widowati, Wahyu; Wargasetia, Teresa Liliana; Zakaria, Teddy Marcus; Gunadi, Michael Sebastian; Halim, Nathanael; Santiadi, Sherly; Kusuma, Hanna Sari Widya; Fauziyah, Nida Firyal
Pharmaceutical Sciences and Research Vol. 10, No. 3
Publisher : UI Scholars Hub

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Abstract

Herbal teas and plant-based medicines have been widely used worldwide for their therapeutic and healing qualities. Rosella (Hibiscus sabdariffa L.) has various benefits in preventing digestive problems, liver disease, fever, and others. Ginger (Zingiber officinale Rosc.) or known as jahe in Indonesia is believed to benefit numerous clinical conditions linked to oxidative stress, including pancreatitis, hypertension, diabetic kidney disease, Alzheimer’s disease, and tumor development. They have been utilized in traditional medical practice to treat conditions such as fever, nausea, and headaches. In this study, we aimed to determine the antioxidant activities of rosella flower tea, ginger tea, and a combination of both, namely RoJa (Rosella-Jahe) tea. Antioxidant activities were analyzed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide (H2O2), 2-2′-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging activities, and Ferric Reducing Antioxidant Power (FRAP) assay, as well as by measuring the amount of total phenolic and flavonoid content. Rosella tea had the greatest activity in the DPPH assay, with an IC50 value of 0.412 mg/ml. Ginger tea had the greatest activity for the ABTS, FRAP, and H2O2 tests, with IC50 values of 12.595 mg/ml, 0.494 mg/ml, and 1.323 mg/ml, respectively. Ginger tea also had the highest amount of total phenolic (3.61 µg GAE/g sample) and flavonoid content (11.81 µg QE/g). In conclusion, ginger tea showed the highest antioxidant activities, as well as total phenolic and flavonoid content, compared to rosella and RoJa tea.
Antioxidant Properties of TeNan Herbal Tea Formulation “Telang (Clitoria ternatea) and Pineapple (Ananas comosus)” Widowati, Wahyu; Wargasetia, Teresa Liliana; Marthania, Meganita; Hanifa , Tazkia Salma; Zakaria, Teddy Marcus; Gunadi, Michael Sebastian; Halim, Natanael; Santiadi, Sheryl
Jurnal Kedokteran Brawijaya Vol. 32 No. 2 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.02.3

Abstract

Herbal teas was are widely consumed by people around the world have high antioxidant activities. The flavor and color combination of specific teas enriches the aroma and appearance of the tea, producing a tea with fresh color and tastier flavor. This study determines the antioxidant activity of telang flower tea (Clitoria ternatea), pineapple tea (Ananas comosus), and the formula of the combination of telang flower tea and pineapple tea called TeNan. The antioxidant activities of herbal teas were measured by 2,2 Diphenyl-1-picrylhydrazyl (DPPH), Hydrogen Peroxide (H2O2), 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), Ferric Reducing Antioxidant Power (FRAP) assay. The total phenol measurement used Gallic Acid Equivalent (GAE), while the flavonoid content measurement used Quercetin Equivalent (QE). The DPPH scavenging activities of telang flower tea, pineapple tea, and TeNan tea (IC50: 17.07%, 11.81%, and 22.22%), H2O2 scavenging activities (IC50: 26.62%, 41.81%, and 96.22%), ABTS-reducing activities (IC50: 2.51%, 3.39%, and 1.02%), and FRAP activities (IC50: 5.56%, 18.67%, and 7.48%). The total phenolic and flavonoid contents of TeNan tea were lower (9.44 μg GAE/100%; 3.46 μg QAE/100% sample concentration) than those of telang flower tea (16.20 μg GAE/100%; 4.88 μg QAE/100% sample concentration) but higher than those of pineapple tea (0.82 μg GAE/100%; 0.17 μg QAE/100% sample concentration). TeNan tea has the higher in ABTS and FRAP activities but lower in H2O2 and DPPH scavenging activities compared to telang flower tea and pineapple tea. In summary, telang tea has stronger antioxidant activity compared to pineapple and TeNan tea in FRAP and H2O2 assays.
Co-Authors Fauziyah, Nida Firyal Halim, Natanael Halim, Nathanael Hanifa , Tazkia Salma Hanna Sari Widya Kusuma, Hanna Sari Widya Marthania, Meganita Santiadi, Sherly Santiadi, Sheryl Teddy Marcus Zakaria Teresa Liliana Wargasetia WAHYU WIDOWATI