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The Future of Energy: Exploring Renewable and Non-Renewable Resources Ahmed, Rashed; Tamim, Md. Tanzimur Rahman
International Journal of Science Education and Science Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/ijses.v2i2.327

Abstract

This comprehensive article delves into the evolving energy landscape, contrasting renewable and non-renewable resources to highlight the global transition toward sustainable energy systems. It underscores the pivotal role of renewable energy sources, such as solar, wind, hydroelectric, and geothermal, as viable solutions to combat climate change and reduce greenhouse gas emissions. The discussion delves into the operational methodologies, tools, and innovations underpinning energy systems, from advanced solar photovoltaics and wind turbines to efficient hydropower and geothermal technologies. Key challenges, such as intermittency, infrastructure costs, and the geographic limitations of renewables, are critically examined alongside the role of non-renewables in current energy mixes. The article also addresses the environmental and societal dimensions, emphasizing ethical guidelines, equity in energy access, and the inclusion of local communities in decision-making. Through a mixed-method research approach, including literature reviews, site visits, and expert interviews, the study offers a nuanced understanding of energy systems. It highlights the importance of integrating sustainable practices and ethical considerations in energy transitions while advocating for technological innovation and international collaboration. The article concludes by emphasizing the critical need for a balanced, multi-faceted strategy to ensure energy security, environmental sustainability, and equitable access for future generations. This research offers a nuanced evaluation of renewable and non-renewable systems. It proposes strategic pathways for integrating diverse energy resources to achieve a balanced, resilient, and sustainable energy future. The study underscores the imperative for international collaboration, technological innovation, and policy advancements to navigate the complexities of this transition, ensuring environmental stewardship and socio-economic benefits for all.
Phytochemical-Based In-Silico Study for Anti-Rabies Drug Discovery: A Pharmaceutical Perspective Ahmed, Rashed
RADINKA JOURNAL OF HEALTH SCIENCE Vol. 3 No. 3 (2026): Radinka Journal of Heatlh Science (RJHS)
Publisher : RADINKA JAYA UTAMA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56778/rjhs.v3i3.480

Abstract

Rabies continues to pose a formidable global health threat, particularly in regions burdened by limited access to vaccines and effective antiviral therapies. This study utilized a high-throughput in silico approach to evaluate the antiviral potential of specific phytochemical compounds against two critical targets of the rabies virus: the glycoprotein (G protein) and the RNA-dependent RNA polymerase (RdRp). Through integrated computational methods—including molecular docking, ADMET profiling, and molecular dynamics (MD) simulations—curcumin, quercetin, and epigallocatechin gallate (EGCG) were identified as primary therapeutic candidates. Molecular docking results revealed robust binding affinity to both target proteins, suggesting a dual-action mechanism capable of inhibiting both viral entry and replication. Furthermore, absorption, distribution, metabolism, excretion, and toxicity (ADMET) analysis indicated favorable pharmacokinetic profiles, characterized by high oral bioavailability and significant blood-brain barrier permeability; the latter is a decisive factor for treating neurotropic infections. Molecular dynamics simulations further validated the structural stability of these protein-ligand complexes under physiological conditions. Collectively, these findings offer a compelling theoretical foundation for developing cost-effective and sustainable anti-rabies interventions, providing a clear trajectory for subsequent in vitro and in vivo experimental validation.