Article Per Year (5 Year)
p-Index From 2021 - 2026
0.983
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Brawijaya The Indonesian Journal of Public Health Devotion: Journal of Research and Community Service Jurnal Kesehatan Kusuma Husada
Sembiring, Thyrister Nina Asarya
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Devotion: Journal of Research and Community Service

 1 
The Effectiveness of Black Mulberry Bark (Morus Nigra L.) Ethanol Extract in Reducing Blood Glucose Levels in Male Mice (Mus Musculus) Induced by Aloxan Saritani, Ayunda Tamara Barito; Indrisari, Maulita; Sembiring, Thyrister Nina Asarya; Nurkalbi, Nuni Rismayanti; Saputra, Agil
Devotion : Journal of Research and Community Service Vol. 6 No. 12 (2025): Devotion: Journal of Community Research
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/devotion.v6i12.25595

Abstract

Diabetes Mellitus (DM) is a disorder of carbohydrate metabolism characterized by a disruption of the body's ability to produce insulin. The bark of the black mulberry stem has a high chemical content of anthocyanins, phenolics, flavanoids and has been known to have many properties. The purpose of this study was to determine the effectiveness of ethanol extract of black mulberry stem bark (Morus nigra L.) on reducing blood glucose levels in male mice (Mus musculus). This research is included in the laboratory-scale experimental type of research. The simplicia of the black mulberry stem is macerated then produces a dry extract. Antidiabetic testing was carried out by dividing 24 mice into 6 groups, namely a healthy control group, a positive control group (glibenchlamid), a negative control group (Na CMC 0.5%), and a 10% b/v dose extract group, a 15% b/v dose extract group, a 20% b/v dose extract group, which was induced with an allocation of 130 mg/kg BB. Based on the results of research that has been carried out, ethanol extract of black mulberry stem bark at a dose of 20% b/v has the highest effect of reducing blood glucose levels with a percentage decrease of 33.51%, compared to doses of 10% and 15%, showing a percentage decrease of 5.51% and 2.36%.
Co-Authors Laurentina, Yoriko Lumingkewas, Gloria Maulita Indrisari, Maulita Mellazulfa, Dhea Sofiana Mohammad Bakhriansyah Muhammad Abdan Shadiqi Nurfianto, Sigit Nurkalbi, Nuni Rismayanti Oktoberia, Theresa Parhusip, Luther Gideon Eric Maruli Rachmad Suhanda Ranti, Dalia Refani, Priska Saputra, Agil Saputri, Grace Dwie Saritani, Ayunda Tamara Barito Setiawan, Frendy Silvia Kristanti Tri Febriana Sinulingga, Erick Darossi Syamsul Arifin Yeni Yeni Yuarta, Ferina Agustia