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All Journal Jurnal Kedokteran Brawijaya JURNAL PENDIDIKAN TAMBUSAI
Ramadhani, Saskia
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Medicine & Pharmacology Social Sciences

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Thromboelastography Profile of Covid-19 Patients Before and After Convalescent Plasma Therapy Administration Fatonah, Siti; Xaveria, Xaveria; Hartanti, Khoirunisah Dwi; Purnamasari, Putri; Ningtyas, Denina Setya; Ramadhani, Saskia
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.11

Abstract

In Covid-19 patients, coagulopathy disorder is commonly characterized as hypercoagulable, although hemorrhagic complications can arise. However, thromboelastography (TEG) is an examination tool with the ability to assess the complete hemostasis process, including primary, secondary, and fibrinolysis stages, closely resembling the in vivo coagulation process. Therefore, this study provides a descriptive analysis of the hemostatic state of Covid-19 patients before and after administration of convalescent plasma therapy using TEG. In this study, the blood sample was collected from 21 Covid-19 patients at RSSA Malang from June to November 2020, followed by a TEG examination, which was performed on the first day of admission and after convalescent plasma therapy administration. The results were analyzed descriptively. Before convalescent plasma therapy, coagulation index (CI) analysis of TEG results in 21 patients showed that 62% exhibited normocoagulability, 23.8% were hypercoagulable, and 14.2% used hypercoagulability. While TEG results after convalescent plasma therapy showed that 71.4% were normocoagulable, 4.7% hypocoagulable, and 23.9% hypercoagulable. Based on TEG parameters, R, K, and MA, before administration of convalescent plasma therapy showed decreased platelet function by 38%, primary fibrinolysis by 5%, secondary fibrinolysis by 10%, platelet hypercoagulability 5%, and 43% was normal. Coagulopathy profile after convalescent plasma therapy showed decreased platelet function by 24%, secondary fibrinolysis by 10%, platelet hypercoagulability by 10%, enzymatic hypercoagulability by 5%, enzymatic and platelet hypercoagulability by 5%, and 48% was normal. TEG in Covid-19 patients showed a hypercoagulable state before and after administration of convalescent plasma therapy
Thromboelastography Profile of Covid-19 Patients Before and After Convalescent Plasma Therapy Administration Fatonah, Siti; Xaveria, Xaveria; Hartanti, Khoirunisah Dwi; Purnamasari, Putri; Ningtyas, Denina Setya; Ramadhani, Saskia
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.11

Abstract

In Covid-19 patients, coagulopathy disorder is commonly characterized as hypercoagulable, although hemorrhagic complications can arise. However, thromboelastography (TEG) is an examination tool with the ability to assess the complete hemostasis process, including primary, secondary, and fibrinolysis stages, closely resembling the in vivo coagulation process. Therefore, this study provides a descriptive analysis of the hemostatic state of Covid-19 patients before and after administration of convalescent plasma therapy using TEG. In this study, the blood sample was collected from 21 Covid-19 patients at RSSA Malang from June to November 2020, followed by a TEG examination, which was performed on the first day of admission and after convalescent plasma therapy administration. The results were analyzed descriptively. Before convalescent plasma therapy, coagulation index (CI) analysis of TEG results in 21 patients showed that 62% exhibited normocoagulability, 23.8% were hypercoagulable, and 14.2% used hypercoagulability. While TEG results after convalescent plasma therapy showed that 71.4% were normocoagulable, 4.7% hypocoagulable, and 23.9% hypercoagulable. Based on TEG parameters, R, K, and MA, before administration of convalescent plasma therapy showed decreased platelet function by 38%, primary fibrinolysis by 5%, secondary fibrinolysis by 10%, platelet hypercoagulability 5%, and 43% was normal. Coagulopathy profile after convalescent plasma therapy showed decreased platelet function by 24%, secondary fibrinolysis by 10%, platelet hypercoagulability by 10%, enzymatic hypercoagulability by 5%, enzymatic and platelet hypercoagulability by 5%, and 48% was normal. TEG in Covid-19 patients showed a hypercoagulable state before and after administration of convalescent plasma therapy
Makna Kultural dalam Lirik Lagu Batak “Pulo Samosir” Karya Nahum Situmorang: Kajian Antropolinguistik Basaria, Ida; Ramadhani, Saskia; Budiman, Ulfiyah; Rahma, Naiya Ar
Jurnal Pendidikan Tambusai Vol. 10 No. 2 (2026): Agustus
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v10i2.38132

Abstract

Penelitian ini dilatarbelakangi oleh pentingnya melestarikan lirik lagu tradisional sebagai teks budaya yang menyimpan kekayaan makna kultural, khususnya pada karya musisi legendaris Batak Toba, Nahum Situmorang. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis makna kultural dalam lirik lagu “Pulo Samosir” melalui perspektif antropolinguistik. Metode yang digunakan adalah kualitatif deskriptif dengan teknik pengumpulan data berupa metode simak bebas libat cakap dan catat. Hasil penelitian menunjukkan adanya empat kategori makna kultural utama: keterikatan mendalam terhadap tanah leluhur, representasi kekayaan alam dan mata pencaharian agraris, peran kuliner tradisional (tuak) dalam interaksi sosial, serta filosofi kematian dan penghormatan leluhur. Simpulannya, lagu ini berfungsi sebagai dokumen kultural yang merekam nilai-nilai filosofis masyarakat Batak Toba. Penelitian ini merekomendasikan integrasi lagu tradisional dalam pembelajaran muatan lokal untuk memperkuat pelestarian budaya daerah.
Makna Kultural dalam Lirik Lagu Batak “Pulo Samosir” Karya Nahum Situmorang: Kajian Antropolinguistik Basaria, Ida; Ramadhani, Saskia; Budiman, Ulfiyah; Rahma, Naiya Ar
Jurnal Pendidikan Tambusai Vol. 10 No. 2 (2026): Agustus
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v10i2.38182

Abstract

Penelitian ini dilatarbelakangi oleh pentingnya melestarikan lirik lagu tradisional sebagai teks budaya yang menyimpan kekayaan makna kultural, khususnya pada karya musisi legendaris Batak Toba, Nahum Situmorang. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis makna kultural dalam lirik lagu “Pulo Samosir” melalui perspektif antropolinguistik. Metode yang digunakan adalah kualitatif deskriptif dengan teknik pengumpulan data berupa metode simak bebas libat cakap dan catat. Hasil penelitian menunjukkan adanya empat kategori makna kultural utama: keterikatan mendalam terhadap tanah leluhur, representasi kekayaan alam dan mata pencaharian agraris, peran kuliner tradisional (tuak) dalam interaksi sosial, serta filosofi kematian dan penghormatan leluhur. Simpulannya, lagu ini berfungsi sebagai dokumen kultural yang merekam nilai-nilai filosofis masyarakat Batak Toba. Penelitian ini merekomendasikan integrasi lagu tradisional dalam pembelajaran muatan lokal untuk memperkuat pelestarian budaya daerah.
Co-Authors Budiman, Ulfiyah Hartanti, Khoirunisah Dwi Ida Basaria Ningtyas, Denina Setya Putri Purnamasari Rahma, Naiya Ar Siti Fatonah Xaveria, Xaveria