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Effectiveness of Moringa oleifera extract supplementation in increasing Glucagon-like peptide-1 (GLP-1) in prediabetic model Rusminingsih, Esri; Susanto, Hardhono; Afifah, Diana Nur; Wibowo, Judiono; Anas, Yance
Jurnal Kebidanan dan Keperawatan Aisyiyah Vol. 20 No. 1 (2024): Juni
Publisher : Universitas Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jkk.3553

Abstract

Prediabetes is a serious global health problem. The prevalence of prediabetes is estimated to be higher than that of diabetes mellitus (DM), and 5%-12.5% of prediabetic patients will develop DM. Epidemiological studies showed that consumption of polyphenol-rich foods impacts blood glucose control and improves insulin resistance. Moringa leaves contain high levels of flavonoids that are effective in glucose control. This study aimed to determine the effect of moringa leaf extract supplementation on increasing GLP-1 levels in prediabetes models. This study used a randomized controlled trial-post-test-only design. Twenty-five male Rattus norvegicus were divided into five groups, namely the normal group, the prediabetes group, and three intervention groups, each given moringa leaf extract at a dose of 75 mg/kgbb, 150 mg / kgbb and 225 mg / kgbb. After 4 weeks of intervention, a GLP-1 examination was conducted. Data analysis using the ANOVA test. There was a significant difference in GLP-1 levels in the intervention group compared to the prediabetes control group (p<0.05). GLP-1 levels increased as the dose given increased. In the intervention group, the dose of 225 mg/kg bw showed the highest increase in GLP-1 levels, but there was no significant difference compared to the 150 mg/kg bw dose group. Moringa leaf extract supplementation is proven to increase GLP-1 in the Rattus norvegicus model. The effect gets better with increasing doses. Further development and testing related to this supplementation are needed so it can be used as a safe non-pharmacological treatment for prediabetes and DM patients.
Pengaruh Video Infografis Edukasi Anemia terhadap Pengetahuan dan Sikap tentang Anemia pada Remaja Putri di SMPN 49 Kota Bandung Maharani, Nadya Puspa; Nurchasanah, Yuni; Pulungan, Yulinda; Wibowo, Judiono
Jurnal Integrasi Kesehatan dan Sains Vol 6, No 1 (2024): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v6i1.13032

Abstract

Remaja putri menjadi kelompok yang rentan anemia karena remaja putri mengalami haid yang menyebabkan kehilangan darah setiap bulan. Beberapa faktor penyebab anemia pada remaja adalah kurang pengetahuan remaja mengenai anemia, gejala, dampak, dan cara mencegahnya. Pemberian edukasi pada usia remaja dianggap paling efektif karena pada usia ini rasa ingin tahu remaja sangat tinggi. Video infografis merupakan salah satu media yang dapat membantu remaja putri meningkatkan pengetahuan dan sikap remaja menjadi lebih positif. Tujuan penelitian ini adalah mengindentifikasi pengaruh pemberian edukasi menggunakan video infografis terhadap pengetahuan dan sikap remaja putri di SMPN 49 Bandung. Penelitian ini merupakan jenis penelitian kuantitif menggunakan desain quasi experimental dengan rancangan pretest-posttest design with control group yang dilaksanakan selama Maret 2023. Pengambilan sampel menggunakan teknik purposive sampling dengan jumlah sampel 35 orang untuk kelompok intervensi maupun kelompok kontrol remaja putri yang memenuhi inklusi dan tidak termasuk eksklusi. Uji hipotesis menggunakan uji Wilcoxon dan Mann Whitney. Hasil penelitian menggunakan uji Wilcoxon mendapatkan hasil ada pengaruh pemberian video infografis terhadap pengetahuan dan sikap remaja putri dengan nilai p 0,000 <0,05. Pada uji beda Mann Whitney didapatkan hasil rerata nilai pengetahuan dan sikap kelompok yang diberikan video lebih tinggi dibanding dengan kelompok yang diberikan e-leaflet dengan selisih mean rank pengetahuan adalah 16,48 dengan nilai p 0,001 pada sikap 15,3 dengan nilai p 0,003. Simpulan, media video infografis lebih efektif meningkatkan pengetahuan dan sikap remaja putri tentang anemia. The Effect of Anemia Education Infographic Video on Knowledge an Attitudes of Young Girls at SMPN 49 BandungAbstractAdolescents are the cluster that is prone to anemia because young women got menstruation, which causes blood loss every month. One of the factors causing anemia in adolescents is the lack of knowledge about anemia, its symptoms, and how to prevent it. Providing education at a young age is considered the most effective because at this age the curiosity of adolescents is very high. Video infographics is one of any methode that can help young women increase their knowledge and attitudes to become more positive. The purpose of this study was to identify the effect of providing education using infographic videos on the knowledge and attitudes of young women at SMPN 49 Bandung. This research is a type of quantitative research using a quasi-experimental design with a pretest-posttest design with a control group during March 2023. Sampling used a purposive sampling technique with a total sample of 35 people for the intervention group and the control group for female adolescents who met the inclusion and exclusion criteria. The results of the study using the Wilcoxon test showed that there was an influence from providing infographic videos on the knowledge and attitudes of young women with p value 0.000 <0.05. In the Mann Whitney different test, the mean value of knowledge and attitudes of the group given the video was higher than the group given the e-leaflet with the difference in the mean rank of knowledge being 16.48 with pvalue 0.001 at an attitude of 15.3 with p value 0.003. From these results it can be concluded that infographic video media has proven to be more effective in increasing the knowledge and attitudes of young women about anemia.