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Studi Fitokimia Dan Farmakologi Morinda Citrifolia Dalam Terapi Kanker: Artikel Review Maria Fransiska Silviani Derosari; Niken Rahmita Khairani; Safanda Tiara Fitri; Miya Hartini Nur Wakhid; Ewalde Yovita Bria; Magdalena Kasmin Belaon Lebuan; Aprilia Puji Astuti; Maulidiyah Cholifah; Agustinus Alfred Seran; Ivan Charles S.Klau; Arista Wahyu Ningsih
DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan Vol. 2 No. 1 (2024): Februari,: Jurnal Ilmu Kesehatan dan Keperawatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59581/diagnosa-widyakarya.v2i1.2227

Abstract

Morinda citrifolia (noni) is a plant that has attracted attention in research as a source of compounds with anti-cancer potential. The aim of this comprehensive understanding is to analyze various studies that have been carried out to investigate the ability of Morinda citrifolia in cancer therapy. The research method involved a qualitative literature study, where we collected ten research articles that had been conducted on various types of cancer cells and the compounds contained in Morinda citrifolia. Research results show that Morinda citrifolia contains a variety of compounds such as anthraquinones, scopoletin, quercetin, and others, which have shown promising anti-cancer activity. In addition, in-silico research also identifies compounds that have the potential to influence key molecular targets in cancer growth pathways. Research results show a variety of anticancer activities associated with these compounds, including their ability to inhibit cancer cell growth, induce apoptosis, reduce oxidative stress, and inhibit cancer cell movement. In several studies, compounds such as morindone, scopoletin, and quercetin have shown promising anticancer activity, especially in certain cancer cell models. In conclusion, Morinda citrifolia shows potential as a source of interesting anti-cancer compounds, and further research is expected to help better understand the potential benefits of this plant in cancer therapy. In this context, further clinical research is needed to validate the efficacy and safety of using Morinda citrifolia in cancer therapy in humans.
Artikel Review : Studi Fitokimia Dan Aktivitas Farmakologi Pada Tanaman Bidara (Ziziphus Mauritiana Lamk) Windi Tri Wahyuni; Fina Nikmatul Wasi’ah; Ismatun Maulidiyah; Elsa Saqila; Sirojul Eilma; Oktafia Damayanti; Brelianty Nevy; Silvi Novita; Agustinus Alfred Seran; Ivan Charles S.Klau; Arista Wahyu Ningsih
Jurnal Ilmiah Dan Karya Mahasiswa Vol. 2 No. 1 (2024): FEBRUARI : JURNAL ILMIAH DAN KARYA MAHASISWA
Publisher : Institut Teknologi dan Bisnis (ITB) Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54066/jikma.v2i1.1287

Abstract

Background: The Bidara plant (Ziziphus mauritiana Lam) is a plant that can be used as a traditional medicine for the treatment of various diseases. Apart from that, the Bidara plant is one type of plant that has the widest distribution and has high economic value. According to several research results, Bidara leaves contain many compounds found in Bidara plants, including saponins, flavonoids, tannins, alkaloids and phenols. Objective: This review journal aims to determine the compounds contained in each part of the Bidara plant and their pharmacological activity. Method: The method used in this article is the literature review method. Results: In this journal review article, there is discussion about Bidara (Ziziphus mauritiana Lam) especially on pharmacological activities such as antibacterial, antimicrobial, antidepressant, anticancer, antipyretic, analgesic, anti-inflammatory and antioxidant in parts of the Bidara plant. Conclusion: in several of these reviews it can be concluded that the part of the Bidara plant that contains many ingredients and has many benefits is the leaves.