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PROFIL DISOLUSI TABLET LEPAS LAMBAT KALIUM DIKLOFENAK MENGGUNAKAN PATI PREGELATINASI TALAS PRATAMA (Colocasia esculenta (L). Schott var. Pratama) Desy Nawangsari; Rani Prabandari; Ammanu Kurniadi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1493

Abstract

Starch is one of the commonly used excipients in tablet preparations. Natural starch has limitations in the form of poor flow rate and compressibility, so it is not suitable for use in the manufacture of tablets by direct compression. One source of plants that produce starch and has not been widely developed is (Colocasia esculenta (L). Schott var. Pratama). The purpose of this study was to modify (Colocasia esculenta (L). Schott var. Pratama) starch by gelatinization used in diclofenac potassium slow-release tablets. This research is a type of laboratory experimental research that begins with the isolation of starch from taro tubers, modification of starch by pregelatinization, manufacture of diclofenac potassium slow release tablet press mass, evaluation of physical properties and finished tablet dissolution tests. The results of the printing mass test showed that the use of (Colocasia esculenta (L). Schott var. Pratama) pregelatinated starch matrix had good flowability. The results of the tablet test showed that the average tablet weight was 209 ± 3.40 mg, the diameter and thickness were 7.69 ± 0.02 and 2.82 ± 0.01 mm respectively, the hardness was 7.00 ± 0.35 kg, the friability was 0. 73 ± 0.27 % and disintegration time 65.33 ± 2.52 minutes and the dissolution results showed that within 8 hours the potassium diclofenac sustained release tablet dissolved 60.20%. Based on the physical properties and dissolution tests performed, it can be concluded that the use of pregelatinated modified starch as a matrix in diclofenac potassium slow-release tablets fulfills the specified test parameters.
Menjaga Kualitas Obat Lewat Edukasi Beyond Use Date (BUD) di Puskesmas Sumbang II Banyumas prabandari, rani; Ammanu Kurniadi; Andrea Arum Sekar; Anisa Rakhma Diantri; Armelia Allya Sandika; Bellina Faradhita Luxfi
Jurnal Dimas Vol 7 No 2 (2025): Jurnal Pengabdian Kepada Masyarakat
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v7i2.117

Abstract

Introduction: Because drug abuse and other issues may arise from the increased use of pharmaceuticals without proper understanding, determining the Beyond Use Date (BUD) is of the utmost importance. Since women may serve as "home pharmacists" and encourage self-sufficiency in health management, it is crucial to educate them about BUD. The goal of this pharmacist-led community service project is to educate housewives about BUD so that they may better manage their medications at home. Approach: Conversation and socializing were the tools used. By comparing the pre- and post-test scores, we were able to determine how helpful the therapy was. We distributed educational materials via BUD-related pamphlets. Higher post-test results compared to the pre-test showed that education on BUD increased knowledge. Conclusion: The PKK (Family Welfare Empowerment) members' understanding of BUD was enhanced by this Pharmacist Community Service activity's use of socializing and discussion to impart information.. Keywords—BUD, Drugs, Education