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All Journal Indonesian Journal of Cancer Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Priyono, Sasongko Hadi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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HUBUNGAN USIA DENGAN DERAJAT DIFERENSIASI KANKER PAYUDARA PADA WANITA Hasfira, Fairuz Izdihar; Oktaviyanti, Ika Kustiyah; Budiwinata, Winardi; Priyono, Sasongko Hadi; Rosida, Lena
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13219

Abstract

Abstract: Breast cancer is a type of cancer that starts in the breast tissue and spreads to the duct or lobule epithelium. As people age, the incidence of breast cancer rises. The aim of this research is to determine the correlation between age and the level of breast cancer differentiation in female patients at RSUD Ulin Banjarmasin. This study used a cross-sectional technique and an analytical observational research design. Purposive sampling was the method used to collect the samples. A total of 64 breast cancer slides met the inclusion criteria for the sample size. A 95% confidence level was used to evaluate the relationship between the two variables using the chi-square test. People under the age of 40 received grade 1 (8.7%), grade 2 (39.1%) and grade 3 (52.2%), while people beyond the age of 40 received grade 1 (14.6%), grade 2 (63.4%), and grade 3 (22%). The chi-square statistical results suggest p-value=0,047. The results showed a correlation between a woman's age and the degree of breast cancer differentiation at RSUD Ulin Banjarmasin. Keywords: breast cancer, grade, age  Abstrak: Kanker payudara ialah suatu keganasan pada jaringan payudara yang berasal dari epitel duktus ataupun lobulus. Insiden dari kanker payudara meningkat sejalan dengan bertambahnya usia. Derajat diferensiasi ialah ukuran perbandingan sel kanker dengan sel normal yang membantu dalam memprediksi prognosis. Penelitian ini memiliki tujuan untuk mengetahui apakah adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita. Penelitian ini memakai rancangan penelitian observasional analitik melalui pendekatan cross sectional. Sampel diambil melalui teknik purposive sampling. Sampel yang memenuhi inklusi ialah 64 slide kanker payudara. Hubungan dari kedua variabel dianalisis menggunakan uji chi-square dengan tingkat kepercayaan 95%. Usia ≤40 tahun didapatkan grade 1 (8,7%), grade 2 (39,1%), dan grade 3 (52,2%), sedangkan usia >40 tahun didapatkan grade 1 (14,6%), grade 2 (63,4%), dan grade 3 (22%). Hasil dari statistik chi-square menunjukkan p-value=0,047. Penelitian ini mendapatkan hasil bahwa adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita di RSUD Ulin Banjarmasin. Kata-kata kunci: kanker payudara, derajat diferensiasi, usia
HUBUNGAN PAPARAN ASAP ROKOK DENGAN KEJADIAN KANKER PAYUDARA PADA USIA MUDA Ambarita, Winona Vida Vita Nathania; Budiwinata, Winardi; Oktaviyanti, Ika Kustiyah; Priyono, Sasongko Hadi; Rosida, Lena
Homeostasis Vol 7, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i3.14611

Abstract

Abstract: Breast cancer is often discovered and diagnosed at a young age which is associated with family history, gene mutations, and poor lifestyle. One of the risk factors is exposure to cigarette smoke. The aim of the research is to determine whether there is a relationship between exposure to cigarette smoke and the incidence of breast cancer at a young age at Ulin Regional Hospital, Banjarmasin. Analytic observational research method, cross sectional research design. Total sampling of breast cancer patients who seek treatment at the Oncology Surgery Polyclinic of Ulin Banjarmasin Hospital for the period January 2020-November 2023 according to the inclusion and exclusion criteria. Data collection using questionnaires related to cigarette smoke exposure. Analysis using the Fisher test. The results were young breast cancer respondents exposed to cigarette smoke (91.1%), very young age exposed to cigarette smoke (8.9%), young age not exposed to cigarette smoke (40.0%) and very young age not exposed to cigarette smoke (60.0%) with a p-value = 0.016. In conclusion, there is a significant relationship between exposure to cigarette smoke and the incidence of breast cancer at a young age. Keywords: breast cancer, young age, cigarette smoke exposure Abstrak: Kanker payudara sering ditemukan dan didiagnosa pada usia muda yang dikaitkan dengan riwayat keluarga, mutasi gen, serta gaya hidup yang buruk. Salah satu faktor risiko yaitu terpapar asap rokok. Tujuan penelitian mengetahui apakah terdapat hubungan paparan asap rokok dengan kejadian kanker payudara pada usia muda di RSUD Ulin Banjarmasin. Metode penelitian observasional analitik, desain penelitian cross sectional. Pengambilan sampel total sampling pasien kanker payudara yang berobat ke Poliklinik Bedah Onkologi RSUD Ulin Banjarmasin periode Januari 2020-November 2023 sesuai kriteria inklusi dan ekslusi. Pengambilan data menggunakan kuesioner terkait paparan asap rokok. Analisis menggunakan uji Fisher. Hasilnya responden kanker payudara usia muda yang terpapar asap rokok (91,1%), usia sangat muda yang terpapar asap rokok (8,9%), usia muda yang tidak terpapar asap rokok (40,0%) dan usia sangat muda yang tidak terpapar asap rokok (60,0%) dengan p-value = 0,016. Kesimpulannya terdapat hubungan bermakna antara paparan asap rokok dengan kejadian kanker payudara pada usia muda. Kata-kata kunci: kanker payudara, usia muda, paparan asap rokok.
A Rare Case of Primary Breast Lymphoma Priyono, Sasongko Hadi; Effendy, Effendy
Indonesian Journal of Cancer Vol 18, No 4 (2024): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i4.1132

Abstract

Introduction: Breast lymphoma (BL) is an uncommon type of extranodal non-Hodgkin lymphoma. Breast lymphoma is challenging to diagnose as its findings are not very specific and usually hard to differentiate from other breast carcinoma. There are no current authorized therapeutic guidelines to date because of the case rarity. In this report, we present a case of detected primary breast lymphoma in a 28-years woman which treated with systemic six cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine (Oncovin), prednisone) chemotherapy, the response remained satisfying until the end of the cycle and no complications were reported.Case Presentation: A 28-year-old woman who had primary breast lymphoma, was treated and had a positive recovery. Clinical examination showed a hard, mobile, erythematous, ulcerating, necrotizing mass in the left breast, approximately 35 cm in the largest dimension. Mammae ultrasound revealed a hypoechoic mass located on the outer upper quadrant presumed malignant (BI-RADS 5). A core biopsy was performed, and an immunohistochemistry test revealed the CD45, CD20, and Ki-67 expression were positive, which finally diagnosed the case as a high-grade B-cell non-Hodgkin’s lymphomaResults: The patient was treated with systemic chemotherapy with six cycles of the R-CHOP protocol, which included administration of cyclophosphamide, doxorubicin, vincristine, rituximab, and prednisone. The patient response remained satisfying until the end of the cycle and no complications were reported.
Co-Authors Ambarita, Winona Vida Vita Nathania Budiwinata, Winardi Effendy Effendy Hasfira, Fairuz Izdihar Ika Kustiyah Oktaviyanti Lena Rosida