Article Per Year (5 Year)
p-Index From 2020 - 2025
1.819
P-Index
This Author published in this journals
All Journal Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) An-Nadaa: Jurnal Kesehatan Masyarakat Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Makara Journal of Science Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Lena Rosida
Department of Histology, Faculty of Medicine, Lambung Mangkurat University
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 19 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 19 Documents
Search

 1   2 
Gambaran Derajat Infiltrasi Sel Radang Dan Infeksi Helicobacter Pylori Pada Biopsi Lambung Pasien Gastritis: Di RSUD Ulin Banjarmasin Tahun 2009-2011 Yulida, Erna; Oktaviyanti, Ika Kustiyah; Rosida, Lena
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.918

Abstract

ABSTRACT: Gastritis is a common gastrointestinal problem all over the world. In Indonesia, the prevalence of gastritis is high enough, it’s about 274.396 cases among 238.452.952 people. The aim of this research is to find out the type and level of inflammation and the infection Helicobacter pylori on gastritis patient in RSUD Ulin Banjarmasin during 2009-2011. The method uses descriptive research by emphasize on preparation of gastric biopsy to find the level of acute inflammation, chronic inflammation dan Helicobacter pylori’s infection based on Updated Sydney System from Endoscopy and Pathology Department. Data were classified by gender, age, and the level of severity. From 52 cases, acute inflammation is occurred in 35 patients with 29 patients (83%) mild, 5 patients (14%) moderate, 1 patient (3%) severe. Chronic inflammation is occurred in 51 patients with 2 patients (4%) mild, 14 patients (27%) moderate, and 35 patients (69%) severe. Helicobacter pylori’s infection is  occurred in 30 patients with 3 patients (10%) mild, 6 patients (20%) moderate, and 21 patients (70%) severe. Keywords : gastritis, acute inflammation, chronic inflammation, Helicobacter pylori ABSTRAK: Gastritis merupakan salah satu masalah kesehatan saluran pencernaan yang paling sering terjadi di dunia. Angka kejadian gastritis di Indonesia cukup tinggi, yaitu 274.396 kasus dari 238.452.952 jiwa penduduk. Tujuan penelitian ini adalah untuk mengetahui jenis dan derajat keparahan infiltrasi sel radang serta infeksi Helicobacter pylori pada pasien gastritis di RSUD Ulin Banjarmasin. Metode penelitian yang digunakan adalah penelitian deskriptif dengan mengumpulkan data tingkat inflamasi akut, kronis dan infeksi Helicobacter pylori berdasarkan Updated Sydney System dari Instalasi Endoskopi dan Instalasi Patologi Anatomi. Data dikelompokkan menurut jenis kelamin, usia, dan tingkat keparahan. Dari 52 preparat, ditemukan inflamasi akut terjadi pada 35 pasien dengan 29 pasien (83%) derajat ringan, 5 pasien (14%) derajat sedang, dan 1 pasien (3%) derajat berat. Inflamasi kronik terjadi pada 51 pasien dengan  2 pasien (4%) derajat ringan, 14 pasien (27%) derajat sedang, dan 35 pasien (69%) derajat berat. Sedangkan infeksi Helicobacter pylori terjadi pada 30 pasien dengan 3 pasien (10%) derajat ringan, 6 pasien (20%) sedang, dan 21 pasien (70%) derajat berat. Kata-kata Kunci: gastritis, inflamasi akut, inflamasi kronis, Helicobacter pylori
PENGARUH PAPARAN BATUBARA TERHADAP JUMLAH MIKRONUKLEUS MUKOSA BUKAL PADA PEKERJA TAMBANG BATUBARA DI KECAMATAN MURUNG PUDAK KABUPATEN TABALONG Renita Rahmad, Renita; Dewi, Nurdiana; Rosida, Lena
Dentino Vol 1, No 2 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACTBackground: Continuous exposure of genotoxic substance such as coal dust can cause DNA damage. Micronucleus is DNA damage caused by genotoxic substance that manifest on buccal mucosa cell. Micronucleus is cytoplasmic chromatic mass with round shaped located close to nucleus and microscopically visible. Purpose: The purpose of this study was to identify effect of coal exposure on the number of micronucleus buccal mucosa on coal miner. Methods: The method of this study was analytic observational with cross-sectional approach. The total sample of this study was 60 respondents divided into 2 groups, each group contained 30 respondents. The data was primary data which was the result of swabbed of buccal mucosa epithelial cells. Results: The result showed the average number of buccal mucosa micronucleus on coal miners was 25,83  13,28 and non-coal miner is 11,10  3,45. Data analyzed with T test Independent and obtained significant different on the number of micronucleus between coal miners and non-coal miner (p=0,000). Conclusion: Based on this study can be concluded that coal dust exposure affected on the number of micronucleus buccal  mucosa on coal miners in Kecamatan Murung Pudak Kabupaten Tabalong. ABSTRAKLatar belakang: Paparan terus menerus dari suatu substansi genotoksik, seperti debu batubara akan menyebabkan suatu kerusakan DNA. Kerusakan  DNA akibat zat genotoksik yang dapat dilihat pada sel mukosa bukal adalah mikronukleus. Mikronukleus merupakan massa kromatik sitoplasmik berbentuk bulat/oval terletak dekat dengan nukleus dan tampak secara mikroskopik. Tujuan: Tujuan penelitian ini adalah mengetahui adanya pengaruh paparan batubara terhadap jumlah mikronukleus mukosa bukal pada pekerja tambang batubara di Kecamatan Murung Pudak Kabupaten Tabalong. Metode: Penelitian ini menggunakan metode penelitian observasional analitik dengan pendekatan cross-sectional. Jumlah sampel pada penelitian ini adalah 60 orang dengan tiap-tiap kelompok masing-masing 30 orang. Data yang diperoleh adalah data primer, yaitu hasil apusan sel epitel mukosa bukal.  Hasil: Hasil penelitian menunjukkan rata-rata jumlah mikronukleus mukosa bukal pada pekerja tambang batubara adalah 25,83  13,28 dan pada bukan pekerja tambang batubara adalah 11,10 3,45. Data dianalisis menggunakan T test Independent dan didapatkan perbedaan bermakna pada rata-rata jumlah mikronukleus antara kelompok pekerja tambang batubara dan bukan pekerja tambang batubara (p=0,000). Kesimpulan: Berdasarkan penelitian ini dapat disimpulkan bahwa paparan batubara berpengaruh terhadap jumlah mikronukleus mukosa bukal pada pekerja tambang batubara di Kecamatan Murung Pudak Kabupaten Tabalong.
HUBUNGAN ANTARA MASA GESTASI DAN KEJADIAN SEPSIS NEONATORUM DI RSUD ULIN BANJARMASIN PERIODE JUNI 2014-JUNI 2015 Dini, Fitri Nur; Andayani, Pudji; Rosida, Lena
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i2.1865

Abstract

Abstract: Neonatal sepsis is a clinical syndrome characterized by symptoms of bacteremia and systemic signs and positive blood cultures showed that during the first month of life. Prematurity and postmaturity risk of morbidity and mortality are high on the gestation age for the occurrence of neonatal sepsis. This study aims to determine the relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin. The design of this study using cross sectional study with retrospective approach. The way the sampling is the purposive sampling were obtained from medical records of patients, then performed statistical analysis using chi-square test with 95%. The number of samples that fulfilled the criteria inclusion in this study as many as 246 cases. The incidence of neonatal sepsis is more common in infants born at 37-42 weeks gestation as many as 25 cases (59.52%). The data not neonatal sepsis who were born with a gestational age <37 weeks or> 42 weeks gained as many as 20 cases (9.80%) and 37-42 weeks gestation obtained as many as 184 cases (90.20%). Chi-square test showed that there is a relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin (p = 0.000) with an odds ratio (OR) 6.256. It is concluded that there is a relationship of gestation age and the incidence of neonatal sepsis (p <0.05) in hospitals Ulin Banjarmasin period June 2014-June 2015 with OR 6.256. Keywords: gestational age, sepsis, neonatal Abstrak: Sepsis neonatorum merupakan suatu sindrom klinis bakteremia yang ditandai dengan gejala dan tanda sistemik serta menunjukkan kultur darah positif yang terjadi pada bulan pertama kehidupan. Prematuritas dan posmaturitas memiliki risiko kesakitan dan kematian yang tinggi pada masa gestasi untuk terjadinya sepsis neonatorum. Penelitian ini bertujuan untuk mengetahui hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin. Rancangan penelitian ini menggunakan cross sectional study dengan pendekatan retrospektif. Cara pengambilan sampel yaitu dengan purposive sampling yang diperoleh dari data rekam medis pasien, kemudian dilakukan analisis statistik menggunakan uji chi-square dengan kepercayaan 95%. Jumlah sampel yang memenuhi kriteria inklusi dalam penelitian ini sebanyak 246 kasus. Kejadian sepsis neonatorum lebih banyak dijumpai pada bayi yang lahir dengan masa gestasi 37-42 minggu yaitu sebanyak 25 kasus (59,52%). Data neonatus tidak sepsis yang lahir dengan masa gestasi <37 minggu atau >42 minggu didapatkan sebanyak 20 kasus (9,80%) dan masa gestasi 37-42 minggu didapatkan sebanyak 184 kasus (90,20%). Uji chi square menunjukkan bahwa terdapat hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin (p=0,000) dengan odds ratio (OR) 6,256. Kesimpulan penelitian ini adalah terdapat hubungan masa gestasi dan kejadian sepsis neonatorum (p<0,05) di RSUD Ulin Banjarmasin periode Juni 2014-Juni 2015 dengan OR 6,256. Kata-kata kunci: masa gestasi, sepsis, neonatus
GAMBARAN FAKTOR RISIKO PASIEN KANKER KOLOREKTAL DI RSUD ULIN BANJARMASIN PERIODE APRIL-SEPTEMBER 2014 Rahdi, Dhia Raihana; Wibowo, Agung Ary; Rosida, Lena
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.172

Abstract

The incidences of colorectal cancer in a developing country such as Indonesia are thought to increase, related to some risk factors that increase the likelihood of colorectal cancer to develop. We have done a study aimed to describe the incidence of colorectal cancer based on risk factor in patients of RSUD Ulin Banjarmasin from April-September 2014. This is a descriptive study using primary data obtained through the use of questionnaire. A total of 39 samples were chosen using non randomized accidental sampling technique. The age group with the most incidence of colorectal cancer was the productive age group (15-64 years old) with as many as 79,49% of all samples. Colorectal cancer patients with a bad diet pattern were as many as 82,05% of all samples. Most of the colorectal cancer patients were diagnosed with colorectal tumor or polyp (69,72%). A total of 30 patients (76,92%) were never diagnosed with ulcerative colitis. As many as 76,93% patients were without any familial history of cancer. The lifestyles of 61,54% colorectal cancer patients were bad lifestyle. Based on the result it can be concluded that diet pattern, age, tumor history, and lifestyle had a significant distribution on the incidences of colorectal cancer. Keywords: colorectal cancer, colorectal polyp, ulcerative colitis.
Hubungan antara Berat Badan Lahir dan Kejadian Asfiksia Neonatorum Fajarwati, Novia; Andayani, Pudji; Rosida, Lena
Berkala Kedokteran Vol 12, No 1 (2016): Februari 2016
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i1.354

Abstract

Abstract:Neonatal asphyxia is a condition where the baby can not breathe spontaneously and regularly soon after birth or shortly after birth. Birth weight is a part of the factors that can cause neonatal asphyxia. Research conducted retrospective observational analytic approach to determine the relationship between birth weight and neonatal asphyxia which uses secondary data from medical records of patients. The study was conducted in August-October 2015 in the NICU and medical record room of RSUD Ulin Banjarmasin. The sampling technique used purposive sampling and obtained a sample of 334 cases. The statistical test used is chi-square test with 95% confidence level. The results showed that of 334 cases of birth weight data showed 17.4% risk birth weight and no-risk birth weight by 82,6%. Neonatal asphyxia 26.3% and 73.7% of no-neonatal asphyxia. Based on the statistical test showed p = 0.674 so that it can be concluded that there is no significant correlation between birth weight and neonatal asphyxia in RSUD Ulin Banjarmasin period June 2014-June 2015.Keywords: neonatal asphyxia, birth weight, risk factor Abstrak: Asfiksia neonatorum adalah suatu keadaan dimana bayi tidak dapat bernapas secara spontan dan teratur segera setelah lahir atau beberapa saat setelah lahir. Berat badan lahir merupakan bagian dari faktor neonatus yang dapat menyebabkan asfiksia neonatorum. Penelitian dilakukan secara observasional analitik dengan pendekatan retrospektif untuk mengetahui hubungan antara berat badan lahir dan kejadian asfiksia neonatorum yang menggunakan data sekunder dari rekam medis pasien. Penelitian dilakukan pada bulan Agustus-Oktober 2015  di ruang NICU dan ruang rekam medis RSUD Ulin Banjarmasin. Teknik pengambilan sampel menggunakan metode purposive sampling dan didapatkan sampel sebanyak 334 kasus. Uji statistik yang digunakan yaitu  uji chi-square dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa dari 334 kasus diperoleh data berat badan lahir berisiko sebesar 17,4% dan berat badan lahir tidak berisiko sebesar 82,6%. Kejadian asfiksia neonatorum sebesar 26,3% dan tidak asfiksia neonatorum sebesar 73,7%.  Berdasarkan hasil uji statistik didapatkan hasil p = 0,674 sehingga dapat disimpulkan bahwa tidak terdapat hubungan yang bermakna antara berat badan lahir dan kejadian asfiksia neonatorum di RSUD Ulin Banjarmasin periode Juni 2014-Juni 2015. Kata-kata kunci: asfiksia neonatorum, berat badan lahir, faktor risiko
DISTRIBUSI POLA DIET PASIEN KANKER KOLOREKTAL DI RSUD ULIN BANJARMASIN PERIODE AGUSTUS OKTOBER 2015 Rahmadania, Emma; Wibowo, Agung Ary; Rosida, Lena
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i2.1872

Abstract

Abstract: Colorectal cancer is a malignancy of epithelial cells of the colon or rectum. Factors associated with an increased risk of this type of cancer include eating habits. The purpose of this study was to determine distribution the dietary patterns in colorectal cancer patients at hospitals Ulin Banjarmasin period from August to October 2015 by a review of fat dietary, protein dietary, fiber dietary  by age and gender. This research is a descriptive observasional with  cross sectional approach. Data was collected using a food frequency questionnaire and interviews. Sampling was conducted with consecutive sampling technique to obtain the sample amounted to 30 patients in accordance with the inclusion criteria. Obtained the age group of patients when first diagnosed with colorectal cancer is highest in the age group 41-60 years (50%) as many as 15 people. Sex ratio of colorectal cancer patients in hospitals Ulin Banjarmasin the period August-October 2015 that men of 15 people (50%) and women of 15 people (50%). Of the 30 respondents, there are 28 (93.4%) patients with colorectal cancer who rarely consume fat, there are 25 (83.4%) patients with colorectal cancer who rarely consume protein, and there were 25 (88.7%) patients with colorectal cancer are rare consuming fiber. Distribution of pattern dietary (fat, protein, fiber)by age and sex obtained the same result that most are in the rare category. Keywords: colorectal cancer, fat, protein, fiber. Abstrak: Kanker kolorektal adalah suatu keganasan dari sel epitel kolon atau rektum. Faktor yang berkaitan dengan peningkatan risiko kanker jenis ini antara lain kebiasaan makan. Tujuan penelitian ini adalah untuk mengetahui distribusi pola diet pasien kanker kolorektal  di RSUD Ulin Banjarmasin periode Agustus-Oktober  2015 dengan tinjauan terhadap diet lemak, diet protein, diet serat berdasarkan usia dan jenis kelamin. Penelitian ini merupakan penelitian yang bersifat deskriptif observasioal dengan pendekatan cross sectional. Data dikumpulkan dengan menggunakan lembar kuesioner food frequency dan wawancara. Pengambilan sampel  dilakukan dengan teknik consecutive sampling sehingga didapatkan sampel berjumlah 30 pasien yang sesuai dengan kriteria inklusi. Didapatkan kelompok usia pasien saat pertama kali terdiagnosis kanker kolorektal terbanyak adalah pada kelompok usia 41-60 tahun (50%) yaitu sebanyak 15 orang. Rasio perbandingan jenis kelamin pasien kanker kolorektal di RSUD Ulin Banjarmasin periode Agustus-Oktober 2015 yaitu laki-laki sebanyak  15 orang (50%)  dan perempuan sebanyak 15 orang (50%). Dari 30 responden, terdapat 28 (93,4%) pasien kanker kolorektal yang jarang mengkonsumsi lemak, terdapat 25 (83,4%) pasien kanker kolorektal yang jarang mengkonsumsi protein, dan terdapat 25 (88,7%) pasien kanker kolorektal yang jarang mengkonsumsi serat. Distribusi pola diet (lemak, protein, serat) berdasarkan usia dan jenis kelamin didapatkan hasil yang sama yaitu paling banyak berada pada kategori jarang. Kata-kata kunci: kanker kolorektal, lemak, protein, serat
HUBUNGAN ANTARA PENGETAHUAN DAN SIKAP TENTANG PERSONAL HIGIENE DENGAN PERILAKU PENCEGAHAN PENULARAN SKABIES Studi Observasional pada Narapidana Anak di Lembaga Pemasyarakatan Anak Klas IIA Martapura Jasmine, Indira Aprilia; Rosida, Lena; Marlinae, Lenie
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 3, No 1 (2016)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v3i1.2730

Abstract

Abstrak Narapidana anak memiliki risiko terhadap skabies karena kurangnya kepedulian akan personal higiene dan perilaku sehat individu. Penelitian ini bertujuan mengetahui hubungan antara pengetahuan dan sikap tentang personal higiene dengan perilaku pencegahan penularan skabies pada narapidana anak di Lembaga Pemasyarakatan Anak Klas IIA Martapura. Penelitian menggunakan rancangan observasional analitik dengan pedekatan cross-sectional. Populasi penelitian dengan total sampling sebanyak 54 orang narapidana anak. Instrumen penelitian menggunakan kuesioner. Variabel bebas adalah pengetahuan dan sikap tentang personal higiene, sedangkan variabel terikat adalah perilaku pencegahan penularan skabies. Uji statistik hasil penelitian menunjukkan sebanyak 72,2% responden memiliki pengetahuan tentang personal higiene kurang, 77,8% responden memiliki sikap tentang personal higiene negatif dan 75,9% responden memiliki perilaku pencegahan penularan skabies buruk. Analisis data dilakukan dengan uji fisher exact didapatkan bahwa ada hubungan antara pengetahuan tentang personal higiene dengan perilaku pencegahan penularan skabies (p=0,000) dan ada hubungan antara sikap tentang personal higiene dengan perilaku pencegahan penularan skabies (p=0,004). Dari hasil tersebut dapat disimpulkan bahwa terdapat hubungan antara pengetahuan dan sikap tentang personal higiene dengan perilaku pencegahan penularan skabies pada narapidana anak di Lembaga Pemasyarakatan Anak Klas IIA Martapura. Kata-kata kunci: pengetahuan, sikap, perilaku, pencegahan penularan skabies AbstractPrisoners child has risks to scabies because of a lack of concern personal hygiene and behavior healthy individual. This study aims to determine the relationship between knowledge and attitudes about personal hygiene to prevent transmission of scabies in the behavior of the child prisoners in penitentiaries children Klas IIA Martapura. This study uses a quantitative method with observational analytic design through cross-sectional method. The study population of 54 inmates of children. The research sample was determined by total sampling technique. The research instrument using a questionnaire. The independent variable of knowledge and attitudes about personal hygiene, while the dependent variable scabies infection prevention behaviors. The results showed the majority of 72.2% of respondents have less knowledge about personal hygiene, 77.8% of respondents have a negative attitude about personal hygiene and 75.9% of respondents had a bad scabies infection prevention behaviors. Results of analysis with fisher exact test shows that there is a relationship between knowledge of personal hygiene with scabies infection prevention behavior (p= 0.000) and there is a correlation between attitudes about personal hygiene with scabies infection prevention behavior (p=0.004). From these results it can be concluded that there is a correlation between knowledge and attitudes about personal hygiene to prevent transmission of scabies in the behavior of the child prisoners in penitentiaries children Klas IIA Martapura.Key words: knowledge, attitude, behavior, prevention of transmission scabies
Molecular Docking of the Interaction between Citrus amblycarpa Extract Contents and Inflammatory Proteins of Hepatic Steatosis Rosida, Lena; Pratiwi, Dewi Indah Noviana; Panghiyangani, Roselina; Utami, Juliyatin Putri; Idhafi, Nasrul; Febriansyah, Muhammad; Budiarman, Andi Azizah Maulidia
Makara Journal of Science Vol. 28, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Citrus amblycarpa possesses various pharmacological activities, such as antioxidant, anticancer, antitumor, hepatoprotective, anti-inflammatory, antidiabetic, antiviral, antibacterial, and antifungal. The main active compounds in C. amblycarpa (including gamma (γ)-aminobutyric acid [GABA], hesperidin, naringin, neoeriocitrin, poncirin, quercetin, and rutin) show potential to interact with the inflammatory proteins in hepatic steatosis (such as nuclear factor kappa beta [NF-kB], tumor necrosis alpha [TNF-alpha], interleukin-6 [IL-6], c-Jun NH2-terminal kinase [JNK], and adiponectin). Molecular docking simulations were performed using Swiss Dock (http://www.swissdock.ch/), and analysis and visualization were conducted using Discovery Studio 4.1. Rutin, poncirin, hesperidin, and neoeriocitrin exhibit high affinities to NF-κB, TNF-alpha, IL-6, and adiponectin proteins, respectively. Similar to curcumin–adiponectin complex interaction, neoeriocitrin–adiponectin interaction involves GLY 223, PRO41, and VAL93 residues. Thus, the most potent inhibitor of hepatic sterosis marker was neoeriocitrin.
HUBUNGAN USIA DENGAN DERAJAT DIFERENSIASI KANKER PAYUDARA PADA WANITA Hasfira, Fairuz Izdihar; Oktaviyanti, Ika Kustiyah; Budiwinata, Winardi; Priyono, Sasongko Hadi; Rosida, Lena
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13219

Abstract

Abstract: Breast cancer is a type of cancer that starts in the breast tissue and spreads to the duct or lobule epithelium. As people age, the incidence of breast cancer rises. The aim of this research is to determine the correlation between age and the level of breast cancer differentiation in female patients at RSUD Ulin Banjarmasin. This study used a cross-sectional technique and an analytical observational research design. Purposive sampling was the method used to collect the samples. A total of 64 breast cancer slides met the inclusion criteria for the sample size. A 95% confidence level was used to evaluate the relationship between the two variables using the chi-square test. People under the age of 40 received grade 1 (8.7%), grade 2 (39.1%) and grade 3 (52.2%), while people beyond the age of 40 received grade 1 (14.6%), grade 2 (63.4%), and grade 3 (22%). The chi-square statistical results suggest p-value=0,047. The results showed a correlation between a woman's age and the degree of breast cancer differentiation at RSUD Ulin Banjarmasin. Keywords: breast cancer, grade, age  Abstrak: Kanker payudara ialah suatu keganasan pada jaringan payudara yang berasal dari epitel duktus ataupun lobulus. Insiden dari kanker payudara meningkat sejalan dengan bertambahnya usia. Derajat diferensiasi ialah ukuran perbandingan sel kanker dengan sel normal yang membantu dalam memprediksi prognosis. Penelitian ini memiliki tujuan untuk mengetahui apakah adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita. Penelitian ini memakai rancangan penelitian observasional analitik melalui pendekatan cross sectional. Sampel diambil melalui teknik purposive sampling. Sampel yang memenuhi inklusi ialah 64 slide kanker payudara. Hubungan dari kedua variabel dianalisis menggunakan uji chi-square dengan tingkat kepercayaan 95%. Usia ≤40 tahun didapatkan grade 1 (8,7%), grade 2 (39,1%), dan grade 3 (52,2%), sedangkan usia >40 tahun didapatkan grade 1 (14,6%), grade 2 (63,4%), dan grade 3 (22%). Hasil dari statistik chi-square menunjukkan p-value=0,047. Penelitian ini mendapatkan hasil bahwa adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita di RSUD Ulin Banjarmasin. Kata-kata kunci: kanker payudara, derajat diferensiasi, usia
HUBUNGAN ANTARA SKOR WIBOWO DAN SKOR RANDHAWA DENGAN TINGKAT KESULITAN KOLESISTEKTOMI LAPAROSKOPI Sorayya, Laina; Wibowo, Agung Ary; Yuliana, Ida; Poerwosusanta, Hery; Rosida, Lena
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13233

Abstract

Abstract: Wibowo and Randhawa score are preoperative scoring systems to predict the difficulty of laparoscopic cholecystectomy. Allegedly, the duration of surgery lengthens as the score increases. Variable difference of the two scores may also be associated with their effectiveness difference in predicting the difficulty of surgery. This study aimed to determine the correlation and difference between Wibowo and Randhawa score with the difficulty of laparoscopic cholecystectomy. This study is an observational analytical correlation and comparative study with a prospective cohort approach. The correlation between the score and the difficulty of surgery was analyzed by simple linear regression test, while the effectiveness difference was analyzed by binomial logistic regression test. There was a weak positive correlation that’s significant between Randhawa score and the difficulty of surgery (r = 0,406; B = 3,017; p = 0,009) and moderate positive correlation that’s significant between Wibowo score and the difficulty of surgery (r = 0,540; B = 3,618; p = 0,001). There was no significant difference between the two scores in predicting the difficulty of surgery (RR 1,523; p = 0.498). An increasing score would lengthen the duration of surgery. Wibowo score was more effective than Randhawa’s, but not significant. Keywords: laparoscopic cholecystectomy, Wibowo score, Randhawa score, level of difficulty, duration Abstrak: Skor Wibowo dan Randhawa merupakan sistem skoring preoperatif untuk memprediksi tingkat kesulitan kolesistektomi laparoskopi. Peningkatan skor diduga berhubungan dengan pemanjangan durasi operasi. Perbedaan variabel penilaian pada kedua skor diduga juga berhubungan dengan perbedaan efektivitasnya dalam memprediksi tingkat kesulitan operasi. Penelitian bertujuan untuk mengetahui hubungan dan perbedaan antara kedua skor tersebut dengan tingkat kesulitan kolesistektomi laparoskopi. Penelitian bersifat observasional analitik korelasional dan komparatif dengan pendekatan kohort prospektif. Hubungan kedua skor dengan tingkat kesulitan operasi dianalisis dengan uji regresi linier sederhana, sedangkan perbedaan efektivitasnya dianalisis dengan uji regresi logistik binomial. Terdapat korelasi positif tingkat lemah yang bermakna antara skor Randhawa dengan tingkat kesulitan operasi (r = 0,406; B = 3,017; p = 0,009) dan korelasi positif tingkat sedang yang bermakna antara skor Wibowo dengan tingkat kesulitan operasi (r = 0,540; B = 3,618; p = 0,001). Tidak terdapat perbedaan yang bermakna antara kedua skor tersebut dalam memprediksi tingkat kesulitan operasi (RR 1,523; p = 0,498). Peningkatan skor menyebabkan pemanjangan durasi operasi. Skor Wibowo lebih efektif daripada skor Randhawa, tetapi tidak bermakna. Kata-kata kunci: kolesistektomi laparoskopi, skor Wibowo, skor Randhawa, tingkat kesulitan, durasi
Co-Authors Agung Ary Wibowo, Agung Ary Al Hasani, Siti Atthahirah Al-Audhah, Nelly Amalia, Aysca Fakhira Ambarita, Winona Vida Vita Nathania Budiarman, Andi Azizah Maulidia Budiwinata, Winardi Dewi Indah Noviana Pratiwi, Dewi Indah Noviana Dewi Nurdiana Dhia Raihana Rahdi, Dhia Raihana Dini, Fitri Nur Eka Yudha Rahman Erna Yulida Febriansyah, Muhammad Harira, Alya Hasanah, Sophia Hasfira, Fairuz Izdihar Ida Yuliana Idhafi, Nasrul Ika Kustiyah Oktaviyanti Indira Aprilia Jasmine, Indira Aprilia Lenie Marlinae Maghfirah, Yolanda Sajjida Maria Ulfah Meitria Syahadatina Noor Novia Fajarwati, Novia Poerwosusanta, Hery Priyono, Sasongko Hadi Pudji Andayani, Pudji Rahmadania, Emma Renita Renita Rahmad, Renita Renny Aditya Ridhana, Achmad Rini, Kusuma Hati Purnama Roselina Panghiyangani Sorayya, Laina Triawanti Triawanti Utami, Juliyatin Putri Wahyuni, Dina Zakia, Sukma Dina