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All Journal Jurnal Pengabdian Magister Pendidikan IPA Jurnal Ilmu Kesehatan
Resti, Nimas
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Dentistry Education Health Professions Nursing Public Health Veterinary

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PRIMARY MYELOPHYBROSIS: RECOGNIZING ONCET TO COMPLICATIONS Resti, Nimas; Rizki, Mohammad; Nurlalwani, Dita Kholida
Jurnal Ilmu Kesehatan Vol 10 No 2 (2022): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v10i2.3568

Abstract

Myelofibrosis is the accumulation of scar tissue in the bone marrow so that blood cells cannot develop properly. Myeloproliferative disorders, myelofibrosis is classified into two, namely primary myelofibrosis and secondary myelofibrosis. In contrast to secondary myelofibrosis, primary myelofibrosis can occur without being preceded by myeloproliferative disorders or other diseases. In a 2013 meta-analysis study in Europe, the incidence of primary myelofibrosis (PMF) was around 0.3 per 100,000 per year. PMF may result from increased expression of inflammatory cytokines, lysyl oxidase, transforming growth factor-β, impaired megakaryocyte function, and aberrant JAK-STAT signaling. The most common clinical features found in patients with PMF are splenomegaly, hepatomegaly, fatigue, anemia, leukocytosis, and thrombocytosis. Currently the only treatment modality capable of prolonging survival or healing potential in MF is allogeneic hematopoietic stem cell transplantation (AHSCT) especially for high or very high risk patients.
Edukasi Kesehatan Mengenai Tonsilitis Pada Pasien Poliklinik THT di RSUD Provinsi NTB Yuliyani, Eka Arie; yudhanto, Didit; Kadriyan, Hamsu; Wedayani, Anak Agung Ayu Niti; Resti, Nimas; Rahmansyah, Nafatasya Ayu; Romadoni, Muhammad Aulia Hikmah
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 2 (2025): April-Juni 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i2.11865

Abstract

Tonsillitis is a disease that is often found in society and can affect all age groups. However, the most common occurrence is in the children's. Tonsillitis can occur acutely, chronically or chronic acute exacerbation, depending on the duration and frequency of infection. The prevalence of tonsillitis globally shows a fairly high number, especially in developing countries. There are several risk factors that play a role in the high prevalence of tonsillitis in Indonesia including air pollution, poor sanitation, and exposure to infection in dense environments. Public awareness is considered lacking in early detection and treatment of tonsillitis often causes delays in treatment. The purpose of this health education is to provide understanding and increase the knowledge of the community visiting the polyclinic at the NTB Provincial Hospital regarding tonsillitis, its risk factors, symptoms, and how to prevent it. In this educational activity, participants were very enthusiastic about following each explanation of the material presented. Some of the education participants also asked questions about tonsillitis and its complications during the discussion session.This can be used as a benchmark as well as a reference and evaluation material for implementing similar activities in the future.
PRIMARY MYELOPHYBROSIS: RECOGNIZING ONCET TO COMPLICATIONS Resti, Nimas; Rizki, Mohammad; Nurlalwani, Dita Kholida
Jurnal Ilmu Kesehatan Vol 10 No 2 (2022): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v10i2.3568

Abstract

Myelofibrosis is the accumulation of scar tissue in the bone marrow so that blood cells cannot develop properly. Myeloproliferative disorders, myelofibrosis is classified into two, namely primary myelofibrosis and secondary myelofibrosis. In contrast to secondary myelofibrosis, primary myelofibrosis can occur without being preceded by myeloproliferative disorders or other diseases. In a 2013 meta-analysis study in Europe, the incidence of primary myelofibrosis (PMF) was around 0.3 per 100,000 per year. PMF may result from increased expression of inflammatory cytokines, lysyl oxidase, transforming growth factor-β, impaired megakaryocyte function, and aberrant JAK-STAT signaling. The most common clinical features found in patients with PMF are splenomegaly, hepatomegaly, fatigue, anemia, leukocytosis, and thrombocytosis. Currently the only treatment modality capable of prolonging survival or healing potential in MF is allogeneic hematopoietic stem cell transplantation (AHSCT) especially for high or very high risk patients.
Co-Authors Anak Agung Ayu Niti Wedayani Didit Yudhanto Kadriyan, Hamsu Nurlalwani, Dita Kholida Rahmansyah, Nafatasya Ayu Rizki, Mohammad Romadoni, Muhammad Aulia Hikmah Yuliyani, Eka Arie