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All Journal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical)
Sumagando, Adolfina
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Uji Aktivitas Antioksidan Ekstrak Etanol Dari Tanaman P. Piloselloides Pada Citrus Microcarpa Dengan Menggunakan Metode DPPH 2,2- Diphenyl-1- Picryhydrazil dengen, Alvina maria; Maarisit, Wilmar; Tombuku, Joke L.; Karauwan, Ferdy A.; Tampa'I, Randy; Sumagando, Adolfina; Ginting, Margaretha S.
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 7 No. 1 (2024): April 2024
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v7i1.442

Abstract

Pyrrosia piloselloides, juga dikenal sebagai tanaman skala naga, telah digunakan dalam pengobatan tradisional untuk daunnya, yang mungkin memiliki efek antioksidan. Penelitian ini bertujuan untuk mengevaluasi potensi antioksidan dari ekstrak etanol  daun Pyrrosia piloselloides yang sering dikenal dengan sisik naga. Aktivitas antioksidan ekstrak etanol dari P. Tanaman piloselloides diukur menggunakan uji 2,2-Diphenyl-1-picrylhydrazyl (DPPH) pada dosis 2,5ppm, 5ppm, 7,5ppm, 10ppm, dan 12,5ppm. Analisis fitokimia digunakan untuk mengidentifikasi senyawa bioaktif yang ada di P. jaringan daun piloselloides. Metabolit sekunder seperti alkaloid, flavonoid, tanin, triterpenoid, saponin, dan fenolik diukur dalam P. daun piloselloides. Nilai IC50 untuk aktivitas antioksidan ekstrak etanol mentah P. Piloselloides Dragon Scale Leaves adalah 3,30 ppm.
Inhibitory Activity Test of Sea Grape (Caulerpa racemosa) Against Salmonella typhi Bacteria Kereh, Indri J.; Lengkey, Yessie K.; Untu, Sonny D.; Ginting, Margaretha S.; Karauwan, Ferdy A.; Tulandi, Selvana S.; Sumagando, Adolfina
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 8 No. 1 (2025): April 2025
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v8i1.500

Abstract

Salmonella typhi is the primary bacterial cause of typhoid fever, which remains a serious health concern in developing countries, including Indonesia. This study aims to evaluate the inhibitory activity of sea grape (Caulerpa racemosa) extract against Salmonella typhi. The extract was obtained through maceration and tested using the agar diffusion method with paper discs at various concentrations (100, 200, 300, and 400 µg/disc). The results showed that C. racemosa extract inhibited the growth of S. typhi with average inhibition zone diameters of 25 mm (100 µg), 27.3 mm (200 µg), 28.8 mm (300 µg), and 29.5 mm (400 µg). The negative control (distilled water) showed no antibacterial activity. Based on classification, all concentrations exhibited very strong antibacterial activity. A higher extract concentration corresponded to greater inhibitory effect. These findings suggest that C. racemosa has potential as a natural antibacterial agent against S. typhi and may be further developed for alternative typhoid treatment.
Co-Authors dengen, Alvina maria Ginting, Margaretha S. Karauwan, Ferdy Kereh, Indri J. Lengkey, Yessie Sonny Untu Tampa'i, Randy Tombuku, Joke Luis Tulandi, Selvana Stien Wilmar Maarisit