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All Journal Indonesian Journal of Tropical and Infectious Disease Lux Mensana: Journal of Scientific Health
Khalisha, Mujahidah
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Earth & Planetary Sciences Health Professions Medicine & Pharmacology Nursing Public Health

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Effectiveness of Vaccines Booster Against Infection, Severe Disease and Death Related to COVID-19 : A Systematic Review and Meta-Analysis Khalisha, Mujahidah; Putri, Melvanda Gisela; Ramadhani, Zulfa Nurfitri; Siahaan, Paulus Parholong; Razan, Rafi Alfian; Antari, Ratna Devi; Hanifah, Adiba Hasna; Utomo, Budi; Fauziyah, Shifa; Muthu, Pandaram
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 2 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i2.45606

Abstract

COVID-19 is an infectious disease as a result of a kind of corona virus. COVID-19 is now a pandemic affecting many countries. This study aims to know the effectiveness of booster vaccines to reduce the severity of illness, confirm infection, hospitalization, death in humans infected with COVID-19. For Specific purpose, to analyze the severity of COVID-19 disease in humans by booster and without booster. The design of this study was a systematic review and meta-analysis based on observational studies, published in databases such as Pubmed, Embase, MedRxiv, Nature and Scopus. In the search for articles, the limitations of 2021 to 2022 are used. This research was analyzed quantitatively through the Review Manager 5.4.1 program. Study was taken from 13 journals that met the criteria for a meta-analysis. With the population aged over 18 years, and using the type of vaccine BNT162b2 or mRNA. The population of this study came from Israel, Italy, England, Qatar, Brazil, Turkey, Puerto-Rico, Northern Bangkok, Vicinities and Thailand. Significant results were obtained for each outcome. The OR values of BNT162b2 booster vaccine against confirmed infection OR 0.16 (95% CI 0.06 – 0.45), against symptomatic disease 0.22 (95% CI 0.11 – 0.44), against asymptomatic disease OR 0.72 (95% CI 0.69 – 0.74), against hospitalization OR 0.12 (95% CI 0.06 – 0.22), against severe disease OR 0.15 (95% CI 0.07 – 0.33), and against death OR 0.10 (95% CI 0.04 – 0.31). Administration booster vaccines is effective in reducing infection rates, disease severity, and deaths from COVID-19. 
THE PROFILE OF HIV INFECTED PREGNANT WOMAN IN TERTIARY HOSPITAL Khalisha, Mujahidah; Akbar, M. Ilham Aldika; Lestari, Pudji
Lux Mensana: Journal of Scientific Health Vol. 1 Issue 4 (2022)
Publisher : jfpublisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56943/jsh.v1i4.216

Abstract

Introduction. In Indonesia, HIV infection is one of the main health problems. Mother or baby with HIV / AIDS have a great opportunity to contribute in maternal and infant mortality. Besides, maternal and infant mortality rates determine the public health quality of a country. This research was conducted based on the negative impact caused by HIV infection and the lack of data on infected pregnant HIV women in Surabaya. This research also expected to find out the main challenges in providing care services, both in terms of health and HIV education for health workers. Method. This research was a descriptive retrospective study to find out the characteristics of HIV infected pregnant women in Regional Public Hospital Dr. Soetomo Surabaya from January-December 2019. There were 36 HIV pregnant women included as a research subject. Results & Analysis. This study shows that the characteristics of HIV infected pregnant women who gave birth in Regional Public Hospital Dr. Soetomo Surabaya has the majority aged of 31-35 years (33.3%), who working as private employees (44.4%), with the latest education is high school (55.6%), married (97.2%), and multigravida (80.6%). Regarding their HIV, most patients (55.6%) had taken ARV for more than 6 months without viral load results (63,8%), and gave birth by C-section (88, 8%). Discussion. Early diagnosis and follow-up of therapy implemented by HIV infected pregnant women and their babies is important to reduce the mother-to-child transmission rate.
Co-Authors Akbar, M. Ilham Aldika Antari, Ratna Devi Budi Utomo Hanifah, Adiba Hasna Muthu, Pandaram Pudji Lestari Putri, Melvanda Gisela Ramadhani, Zulfa Nurfitri Razan, Rafi Alfian Shifa Fauziyah Siahaan, Paulus Parholong