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All Journal International Journal of Public Health Excellence (IJPHE) MPSJ
Hendra Herman
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Health Professions Medicine & Pharmacology Nursing Public Health

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A Narrative Review: Efficacy and Safety the Used of Corticosteroids as an Adjunct Therapy for Rheumatoid Arthritis Hendra Herman; Irma Rachma Hanifah; Kamri, Andi Maulana
International Journal of Public Health Excellence (IJPHE) Vol. 2 No. 1 (2022): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v2i1.262

Abstract

Rheumatoid Arthritis (RA) is an autoimmune disease characterized by inflammation of the joints. The selection of corticosteroids with broad indications is used as an adjunct therapy because of its anti-inflammatory activity and immune suppression. The research aimed to determine the efficacy and safety profile of corticosteroids in rheumatoid arthritis patients. The method used was a literature review with a narrative review design based on inclusion and exclusion criteria through the PubMed and Google Scholar databases. The results showed that the Prednisone group with varying doses of 5 mg; 6.25 mg; 10 mg gave better efficacy than the placebo group or Methotrexate monotherapy against disease activity with the DAS28 parameter. Prednisone safety was observed from the side effects, hypertension; hyperglycemia and adverse events, headache; reported diarrhea. The review show that the use of Prednisone tab 10 mg/day provided the best efficacy in the first 3 months (p<0.001) with the DAS28 parameter which achieved the greatest clinical remission. The side effects of Prednisone could not be concluded between the effect of dose and the level of drug safety.
Profil Peresepan Obat Diabetes Melitus di RSUD Prof. Dr. H. M. Anwar Makkatutu Kab.Bantaeng Periode Agustus – Oktober 2022 Nur hayat; Hendra Herman; Iskandar Zulkarnain
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Diabetes mellitus (DM) is a progressive chronic disease characterized by the body's inability to metabolize carbohydrates, fats and proteins, causing hyperglycemia (high blood sugar). At Prof. Hospital Dr. H. M. Anwar Makkatutu Diabetes Mellitus is a disease that has the highest prevalence based on previous observations. The purpose of this study is to obtain data on prescribing profiles through administration screening, pharmaceutical screening and clinical screening on diabetes mellitus drugs given to patients at Prof. Hospital. Dr. H. M. Anwar Makkatutu, Bantaeng Regency for the period August-October 2022. The research method used is descriptive. The population used was all diabetes mellitus prescriptions (255 recipes) during the study period. Administrative screening showed that 100% of prescriptions did not include height. Pharmaceutical screening yielded 100% of prescriptions did not include instructions for using the drug. Clinical screening found potential drug interactions in 69 cases. Of the 69 cases of interaction that occurred, 89.86% were moderate. The conclusion of this study is the profile of diabetes mellitus drug prescribing in patients at Prof. Hospital. Dr. H. M. Anwar Makkatutu, Bantaeng Regency, has not met the standards of pharmaceutical services in hospitals.
Pengkajian Resep Racikan Anak di Rumah Sakit Mega Buana Kota Palopo A. Sitti Nur Ramadani Baso; Hendra Herman; Iskandar Zulkarnain
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Pengkajian resep merupakan suatu kegiatan pengkajian pada resep berdasarkan aspek administrasi, farmasetik dan Juga klinis. Penelitian ini dilakukan untuk mengetahui kesesuaian pengkajian resep racikan anak di Rumah Sakit Mega Buana Kota Palopo berdasarkan Permenkes No. 72 Tahun 2016 tentang standar pelayanan kefarmasian di Rumah Sakit. Penelitian ini menggunakan metode deskripsi dengan jenis data retrospektif. Sampel yang digunakan dalam penelitian ini sebanyak 132 resep pada periode Juni – September 2022. Hasil yang di dapatkan pada kesesuaian aspek administrasi yaitu 59,56 %, aspek farmasetik yaitu 66,66%, dan pada aspek klinis komponen interaksi obat sebanyak 96 resep dengan persentase 72,72%
Profil Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD La Temmamala Kabupaten Soppeng Akram Resa Nugraha; Hendra Herman; Vina Purnamasari
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Hypertension has become one of the deadly diseases in both Indonesia and the world. Hypertension (or high blood pressure) is defined as a condition when the blood pressure is above 140/90 mmHg. According to the profile of the Health Department of South Sulawesi Province in 2018, Soppeng Regency has the highest rate of people with hypertension at 98,79% with 4.997 from 5.058 patients. The purpose of this research is to describe the usage of anti-hypertension medicines to the patients at Latemmalala Regional Public Hospital, Soppeng Regency, in the period between June-December 2022. This research is considered a quantitative research with the descriptive method and observational research design, as well as the retrospective approach that begins with the documentary research taken from the patient’s medical records. The result shows that the characteristic rate of the patients according to the gender is mostly found on females, with 20 patients being confirmed (67,5%), for the ages between 60-69 years old, 15 patients are confirmed (46,9%), and the following disease that is also found on the patients with hypertension is the kidney failure, where there are 14 patients being confirmed (20%). The most used type of medicine is the calcium channel blocker (CCB), another medicine that is also often used is the 57 units of amlodiphine (37,5%), and the most-used combined medicines are 9 units of amlodiphine and furosemid (39,1%). According to the accuracy and the inaccuracy of the medical usage, the accuracy is 100% and the inaccuracy is 0%.
PROFIL PENYIMPANAN OBAT DI GUDANG INSTALASI FARMASI RUMAH SAKIT MITRA MANAKARRA MAMUJU SULAWESI BARAT Resky Nov Hokilia; Hendra Herman; A. hasrawati
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Pharmaceutical services in hospitals including the management of pharmaceutical supplies including drug storage to pay attention to storage so that errors do not occur during the drug storage process and drug storage is a very important step in maintaining the quality of medicines. Drug storage must guarantee the quality and safety of the drug in accordance with pharmaceutical requirements. The purpose of this study was to determine the profile of drug storage in the Pharmacy Installation Warehouse at Mitra Manakarra Mamuju Hospital, West Sulawesi and its compliance with regulations in force in Indonesia. This study used a descriptive method by conducting interviews and observations. The respondents in this study consisted of the person in charge of the pharmacy and the person in charge of the warehouse at the Pharmacy Installation at Mitra Manakarra Hospital Mamuju, West Sulawesi. Collecting data in research by means of observation, interviews and data analysis. Analysis Percentage of storage areas in good condition with a yield value of 93.1%, storage areas for narcotics, psychotropics and precursors in good condition with a yield value of 100%, method and system aspects in good condition with a yield value of 91.6% and stock cards in good condition with yield values 90%.
Profil Peresepan Penggunaan Obat Gastritis Pada Pasien Rawat Jalan di RSUD Batara Guru Belopa Periode Januari-Maret 2023 Dian Indri Muris; Hendra Herman; A. hasrawati
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Gastritis is a stomach disease caused by inflammation of the stomach wall. That is why gastritis is often referred to as inflammation of the stomach. The causes of gastric disorders include infection with Helicobacter pylori bacteria, side effects of using non-steroidal anti-inflammatory drugs (NSAIDs), poor lifestyle, and prolonged stress. This study aims to determine the prescription of gastritis drugs in outpatients at Batara Guru Belopa Hospital based on patient characteristics (age and gender), as well as to see the suitability and classification of gastritis drugs which include dose and frequency, drug type parameters, drug combinations, and drug interactions prescribed. The method in this study is descriptive research with retrospective research data type. The sample used in this study used purposive sampling method with sampling based on inclusion criteria where 314 gastritis prescription sheets were obtained. Based on the results obtained, it was found that female patients had a greater percentage than men with 208 prescriptions (66.24%), while the largest age group of gastritis patients was the late adulthood age group with ages 35-54 having the largest percentage of 26.75%. The use of gastritis drugs based on the most prescribed type of single therapy is Omeprazole as many as 79 prescriptions (49.69%), the most prescribed type of two drug combination therapy is Omeprazole and Sucralfat as many as 47 prescriptions (31.97%), and for the type of three drug combination therapy the most prescribed is Omeprazole + Ranitidine + Sucralfat (42.85%).
Co-Authors A Hasrawati A. Sitti Nur Ramadani Baso Akram Resa Nugraha Andi Maulana Kamri Dian Indri Muris Irma Rachma Hanifah Nur hayat Resky Nov Hokilia RR. Ella Evrita Hestiandari Vina Purnamasari