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All Journal Jurnal EduHealth PharmaCine : Journal of Pharmacy, Medical and Health Science
Sa’adah, Cantika Nurul
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Metode Isolasi Flavonoid pada Tumbuhan di Indonesia Annisa, Bunga Nur; Tama, Aditia Putra; Sa’adah, Cantika Nurul; Sary , Nena Vauziah
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 2 No 1 (2021): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v2i1.5578

Abstract

Tumbuhan merupakan keanekaragaman hayati yang selalu ada di sekitar kita baik secara liar maupun dibudidayakan. Tumbuhan memiliki dua kelompok senyawa metabolit yakni metabolit primer dan metabolit sekunder. Metabolit sekunder berfungsi dalam perkembangbiakan dan pertahanan tumbuhan. Salah satu contoh metabolit sekunder adalah flavonoid. Tujuan dari artikel ini adalah untuk mengidentifikasi metode yang tepat dalam mengisolasi flavonoid pada tumbuhan di Indonesia. Metode yang digunakan yaitu tinjauan literatur dengan teori-teori yang relevan. Hasil dari tinjauan lima tumbuhan dapat disimpulkan bahwa isolasi senyawa flavonoid dilakukan dalam lima tahap yaitu ekstraksi, fraksinasi, skrining, pemisahan dan pemurnian, serta identifikasi isolat.
Standardization of Anthocyanin Compounds in Plants in Indonesia: Literature Review Agustin, Annastya Eka; Mierza , Vriezka; Annisa, Bunga Nur; Sa’adah, Cantika Nurul; Prasetyo, Fajar; Lubis, Christina Febiola
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.134 KB)

Abstract

Anthocyanins are secondary metabolites belonging to the flavonoid group which act as pigments or coloring agents in plants that give red, blue and purple colors to flowers, fruits and vegetables. Anthocyanins have several pharmacological activities such as antioxidants, anti-carcinogenic, preventing impaired liver function, anti-hypertensive, and anti-diabetic. The anthocyanin structure consists of an aglycone form which is sterified by several sugar groups (glycones) and acyl groups in several anthocyanin compounds. In an effort to maintain the standard of a drug made from natural ingredients, the process of standardization of active compounds can be carried out to guarantee and maintain safety, quality uniformity and efficacy. This review was conducted to identify the anthocyanins contained in an extract by means of thin layer chromatography (TLC), UV-Vis spectrophotometer, thin layer chromatography-densitometry, and high performance liquid chromatography (HPLC). The research methodology used is in the form of literature review with reference sources related to the review topic obtained from various sources, such as Pubmed, Science Direct, and Google Scholar.
Co-Authors Agustin, Annastya Eka Annisa, Bunga Nur Lubis, Christina Febiola Mierza , Vriezka Prasetyo, Fajar Sary , Nena Vauziah Tama, Aditia Putra