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All Journal Jurnal EduHealth PharmaCine : Journal of Pharmacy, Medical and Health Science
Agustin, Annastya Eka
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Metode Pemisahan Fitokimia Tanin pada Tanaman Herbal Indonesia Zakiyah, Wildani; Agustin, Annastya Eka; Fauziah, Anisa; Maharani, Dhavina; Mukti, Galih Ibnu
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 2 No 1 (2021): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v2i1.5582

Abstract

Pemisahan kimia adalah cara untuk memisahkan bagian tertentu dari suatu campuran. Pemisahan fitokimia secara umum sistematisnya adalah pembuatan simplisia, skrining, ekstraksi, fraksinasi, isolasi, dan identifikasi senyawa. Penelitian ini bertujuan untuk mengetahui tahapan pemisahan yang cocok terhadap senyawa tannin yang cenderung polar, baik tannin terkondensasi atau proantosianidin maupun tannin terhidrolisis. Metode penelitian ini dengan melakukan penelusuran terhadap beberapa literatur jurnal ilmiah yang telah terpublikasi sebagai acuan penulisan. Hasil penelitian menunjukkan bahwa pada sejumlah tanaman yang dijadikan sampel terbukti memiliki kandungan tannin. Hal ini dilakukan melalui beberapa metode pemisahan yang efektif yakni, fraksinasi berupa ECC atau kromatografi, isolasi berupa KLT atau KLTP, serta pengidentifikasian senyawa melalui Spektrofotometer UV-VIS dan FTIR.
Pharmacoeconomic Literature Review: Antibiotics As A Cost-Effective Treatment Of Tyfoid Fever Agustin, Annastya Eka; Salman, Salman
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.066 KB)

Abstract

Demam tifoid merupakan penyakit yang sering kita jumpai pada masyarakat di Indonesia. Dengan pengobatan lini pertama yaitu antibiotik tepatnya golongan kloramfenikol. Namun, masih banyak pilihan terapi pengobatan antibiotik untuk demam tifoid seperti golongan sefalosporin, ampisilin, fluorokuinolon. Dengan golongan yang berbeda, sudah pasti mereka memiliki harga satuan yang berbeda pula. Hal ini dilakukan untuk pasien demam tifoid rawat inap dengan mempertimbangkan sisi cost-effectiveness dan level terapi yang diinginkan. Biaya efektif dapat ditentukan melalui empat kategori. Keempat kategori ini berpacu dengan hasil perhitungan ACER dan ICER.
Standardization of Anthocyanin Compounds in Plants in Indonesia: Literature Review Agustin, Annastya Eka; Mierza , Vriezka; Annisa, Bunga Nur; Sa’adah, Cantika Nurul; Prasetyo, Fajar; Lubis, Christina Febiola
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.134 KB)

Abstract

Anthocyanins are secondary metabolites belonging to the flavonoid group which act as pigments or coloring agents in plants that give red, blue and purple colors to flowers, fruits and vegetables. Anthocyanins have several pharmacological activities such as antioxidants, anti-carcinogenic, preventing impaired liver function, anti-hypertensive, and anti-diabetic. The anthocyanin structure consists of an aglycone form which is sterified by several sugar groups (glycones) and acyl groups in several anthocyanin compounds. In an effort to maintain the standard of a drug made from natural ingredients, the process of standardization of active compounds can be carried out to guarantee and maintain safety, quality uniformity and efficacy. This review was conducted to identify the anthocyanins contained in an extract by means of thin layer chromatography (TLC), UV-Vis spectrophotometer, thin layer chromatography-densitometry, and high performance liquid chromatography (HPLC). The research methodology used is in the form of literature review with reference sources related to the review topic obtained from various sources, such as Pubmed, Science Direct, and Google Scholar.
Study Of Molecular Docking On Compounds With Potential As Anti-Inflammatory Ravelliani, Andien; Nisrina, Hasna'; Sari, Lala Komala; Marisah, Marisah; Agustin, Annastya Eka; Maharani, Dhavina; Utami, Marsah Rahmawati; Nurfadhila, Lina
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.665 KB)

Abstract

Inflammation is a protective response caused by damage to certain tissues. Anti-inflammatory is a substance or drug used to treat redness, increased body temperature, swelling, pain and loss of function of an organ. Steroid and non-steroidal anti-inflammatory drugs have many side effects, so studies are needed to develop new drugs to minimize side effects and improve therapeutic effects. The method used is literature review from journals and articles obtained from Google Scholar in 15 journals. The purpose of the literature review is to find out the study of the development of new drugs from several compounds that have potential as anti-inflammatories. Secondary metabolites that have potential as anti-inflammatory include essential oils, flavonoids, alkaloids, terpenoids, and anthocyanins. Secondary metabolites will interact with the cyclooxygenase (COX) enzyme which is the main mediator of inflammation. The results obtained from the 15 compounds contain these secondary metabolites so they have the potential as anti-inflammatory.
Identification Of Carbohydrate, Protein And Fat Levels In Flour, Cheese, Milk And Yoghurt Through Several Test Methods Tyasna, Putri Setya; Agustin, Annastya Eka; Maharani, Dhavina; Utami, Marsah Rahmawati; Nurfadhilah, Lina
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.145 KB)

Abstract

Food is incoming substance to in body human and processed in a manner chemical and biological like carbohydrates , proteins, and fats. each of third substance this have very important role for body . Carbohydrate useful as one source energy , increase the sweet taste , regulate the process of glucose blood , and can solve fatty acids. Proteins play a role in metabolic processes , catalysts enzymatic , antibody , and carrier signal in a manner biological . Useful fat as warmer body , adjustment with change temperature , and protect body from crash . For knowing how much many content of fat , protein, and carbohydrates contained in a food or drink so need done testing in a manner qualitative and quantitative , testing this depending on the sample being tested and the effect temperature nor ingredient standard used . The purpose of the literature review is to determine and compare the levels of carbohydrates, proteins and fats in samples of flour, milk, cheese and yogurt through various test methods.
Co-Authors Annisa, Bunga Nur Fauziah, Anisa Lubis, Christina Febiola Maharani, Dhavina Marisah, Marisah Marsah Rahmawati Utami Mierza , Vriezka Mukti, Galih Ibnu Nisrina, Hasna' Nurfadhila, Lina Nurfadhilah, Lina Prasetyo, Fajar Ravelliani, Andien Salman Salman Sari, Lala Komala Sa’adah, Cantika Nurul Tyasna, Putri Setya Zakiyah, Wildani