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All Journal Journal of Midwifery and Nursing Journal of Experimental and Clinical Pharmacy (JECP)
Begum, Nanda Sayyida
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Identifikasi Senyawa Flavonoid Fraksi Etanol Bintang Laut (Linckia laevigata) di Perairan Bolaang Mongondow Mappa, Moh. Rivaldi; Bahi, Rizky Resvita R.; Sarman, Sarman; Fauzan, Moh Rizki; Begum, Nanda Sayyida
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 2 (2024): August 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i2.1103

Abstract

Bintang laut merupakan organisme laut yang menghasilkan senyawa bioaktif, salah satunya flavonoid. Flavonoid berkhasiat sebagai antioksidan, anti-penuaan, anti-inflamasi, antivirus, dan lain sebagainya. Penelitian ini bertujuan untuk mengidentifikasi kandungan senyawa flavonoid dari fraksi etanol bintang laut yang diperoleh dari pesisir pantai Desa Maelang Kabupaten Bolaang Mongondow menggunakan uji kualitatif pereaksi kimia dan metode kromatografi lapis tipis (KLT). Hasil penelitian menunjukkan bahwa bintang laut yang diperoleh dari pesisir pantai Desa Maelang Kabupaten Bolaang Mongondow positif mengandung senyawa flavonoid yang ditandai dengan perubahan warna dari jingga ke hijau kehitaman pada uji menggunakan pereaksi kimia dan terbentuknya pola noda berwarna hijau dengan nilai Rf 0,8 pada pelat KLT yang dibandingkan dengan baku standar kuersetinStarfish are marine organisms that produce bioactive compounds, one of which is flavonoids. Flavonoids are efficacious as antioxidants, antiaging, anti-inflammatory, antiviral and so on. This research aims to identify the content of flavonoid compounds from the ethanol fraction of starfish obtained from the coast of Maelang Village, Bolaang Mongondow Regency using qualitative tests of chemical reagents and the thin layer chromatography (TLC) method. The results of the research showed that starfish obtained from the coast of Maelang Village, Bolaang Mongondow Regency were positive for containing flavonoid compounds which were characterized by a color change from orange to blackish green in the test using chemical reagents and the formation of a green stain pattern with an Rf value of 0.8 on the TLC plate which was compared with the standard quercetin
Article review: Cost effectiveness analysis of antihypertensive amlodipine compared to captopril in health care facilities Astuti, Windi; Kuna, Moh. Rasyid; Begum, Nanda Sayyida; Nadila Ginoga, Nur Wahyu; Sugeha, Muhammad Anugrah
Journal of Midwifery and Nursing Vol. 7 No. 2 (2025): May: Law Science and Field
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v7i2.6095

Abstract

Hypertension, also known as high blood pressure, is a disease characterized by an increase in systolic blood pressure exceeding 140 mmHg and diastolic blood pressure exceeding 90 mmHg, in several measurements with a time of five minutes and with sufficient rest.  The purpose of this study is to determine the cost effectiveness of hypertension therapy by using a comparison of amlodipine and captopril drug therapy in health service facilities. The method chosen was a literature study taken from journals and the results of previous research from various references related to the cost-effectiveness of antihypertensive therapy. Based on several journal literature or scientific publications that have been researched regarding the cost-effectiveness of amlodipine antihypertensive therapy compared to captopril, the results show that amlodipine has a higher effectiveness compared to captopril based on ACER and ICER values from several previous studies. Based on 10 literatures that have been analyzed, 7 literatures state that amlodipine antihypertensive is more Cost-Effective compared to captopril antihypertensive.
Co-Authors Bahi, Rizky Resvita R. Fauzan, Moh Rizki Kuna, Moh. Rasyid Mappa, Moh. Rivaldi Nadila Ginoga, Nur Wahyu Sarman Sarman Sugeha, Muhammad Anugrah Windi Astuti