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All Journal Jurnal Ilmu Kefarmasian Indonesia Journal of Experimental and Clinical Pharmacy (JECP)
Daud, Rizka Puji Astuti
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Skrining Fitokimia dari Ekstrak Metanol Akar Kelor (Moringa oleifera L.) Basri, Insyira Fadliana; Mohamad, Fihrina; Slamet, Nangsih Sulastri; Imran, Arlan K.; Daud, Rizka Puji Astuti; Yunus, Fitriah Ayu Magfirah; Wicita, Prisca Safriani; Basri, Rakhmadhana Fitraeni
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 2 (2022): August 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i2.345

Abstract

Tanaman kelor tumbuh di daerah tropis dan telah dikenal oleh masyarakat sebagai sayur dan berkhasiat sebagai obat tradisional. Sangat jarang ditemukan penelitian yang mengidentifikasi senyawa metabolit sekunder pada bagian akar kelor. Oleh karena itu, penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder yang terkandung dalam akar kelor (Moringa oleifera L.) yang berasal dari Desa Talulobutu, Kabupaten Bone Bolango. Metode penelitian ini menggunakan reagen Mayer dan reagen Dragendorff untuk mengidentifikasi senyawa alkaloid, reagen NaOH 4% untuk mengidentifikasi senyawa tanin, reagen Pb(C2H3O2)2 10% untuk megidentifikasi senyawa flavonoid, dan uji buih menggunakan aquadest panas untuk megidentifikasi senyawa saponin.Moringa plant grows in the tropics and has been known by the public as a vegetable and efficacious as traditional medicine. It is very rare to find studies that identify secondary metabolites in the roots of Moringa. Therefore, this study aims to identify secondary metabolites contained in Moringa root ( Moringa oleifera L.) originating from Talulobutu Village, Bone Bolango Regency. This research method uses Mayer's reagent and Dragendorff's reagent to identify alkaloid compounds, 4% NaOH reagent to identify tannin compounds, Pb(C2H3O2)2  10% reagent to identify flavonoid compounds, and foam test using hot aquadest to identify  saponins compounds.
The effectiveness of butterfly pea hydrogel film (Clitoria Ternatea) with chitosan and poly-vinyl-alcohol based as diabetic wound healing Wicita, Prisca Safriani; Daud, Rizka Puji Astuti; Sapiun, Zulfiayu; Yahya, Cindy; Wantaa, Nurunnisa; Mohamad, Fihrina; Imran, Arlan K.; Hartati, Hartati; Husain, Fadli
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1483

Abstract

Butterfly pea possesses antioxidant activities with IC50 470 μg/ml of wound healing acceleration quality. Hydrogel for diabetic wound healing due to its physical characteristic that binds water, aside from its qualities that wets the surface and bio-compatibility in the body. This study aimed to identify effectivity test of hydrogel film preparation with butterfly pea (clitoria ternatea l.) Water extract for diabetic wound healing, employing true experimental method which involves 12 rats divided into 4 groups. The control group was treated without the Hydrogel (HET) or HET0 on hyperglycemic rats, HET1 (2%), HET2 (5%), and HET3 (7.5%). The findings revealed wounds treated with HET0 was healed in 9 days with 11.13 mm of diameter (100%), HET1 was healed in 6 days with 15.22 mm of diameter (100%), HET2 that was healed in 4 days with 11.29 mm of diameter (100%), and HET3 that was healed in 8 days with 9.05 mm of diameter (100%). It was concluded that the effectivity test revealed that the best formula is HET2 (5%) healed in 4 days with 11.29 mm of diameter in 100%.
Co-Authors Basri, Insyira Fadliana Basri, Rakhmadhana Fitraeni Fihrina Mohamad Hartati Hartati Husain, Fadli Imran, Arlan K PRISCA SAFRIANI WICITA Sapiun, Zulfiayu Wantaa, Nurunnisa Yahya, Cindy Yunus, Fitriah Ayu Magfirah