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All Journal Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Keselamatan Kesehatan Kerja dan Lingkungan Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Info Kesehatan
Yunus, Fitriah Ayu Magfirah
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Skrining Fitokimia dari Ekstrak Metanol Akar Kelor (Moringa oleifera L.) Basri, Insyira Fadliana; Mohamad, Fihrina; Slamet, Nangsih Sulastri; Imran, Arlan K.; Daud, Rizka Puji Astuti; Yunus, Fitriah Ayu Magfirah; Wicita, Prisca Safriani; Basri, Rakhmadhana Fitraeni
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 2 (2022): August 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i2.345

Abstract

Tanaman kelor tumbuh di daerah tropis dan telah dikenal oleh masyarakat sebagai sayur dan berkhasiat sebagai obat tradisional. Sangat jarang ditemukan penelitian yang mengidentifikasi senyawa metabolit sekunder pada bagian akar kelor. Oleh karena itu, penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder yang terkandung dalam akar kelor (Moringa oleifera L.) yang berasal dari Desa Talulobutu, Kabupaten Bone Bolango. Metode penelitian ini menggunakan reagen Mayer dan reagen Dragendorff untuk mengidentifikasi senyawa alkaloid, reagen NaOH 4% untuk mengidentifikasi senyawa tanin, reagen Pb(C2H3O2)2 10% untuk megidentifikasi senyawa flavonoid, dan uji buih menggunakan aquadest panas untuk megidentifikasi senyawa saponin.Moringa plant grows in the tropics and has been known by the public as a vegetable and efficacious as traditional medicine. It is very rare to find studies that identify secondary metabolites in the roots of Moringa. Therefore, this study aims to identify secondary metabolites contained in Moringa root ( Moringa oleifera L.) originating from Talulobutu Village, Bone Bolango Regency. This research method uses Mayer's reagent and Dragendorff's reagent to identify alkaloid compounds, 4% NaOH reagent to identify tannin compounds, Pb(C2H3O2)2  10% reagent to identify flavonoid compounds, and foam test using hot aquadest to identify  saponins compounds.
AN OVERVIEW OF THE COMMUNITY KNOWLEDGE LEVEL TOWARDS THE USE OF GENERIC DRUGS IN TUPA VILLAGE, NORTH BULANGO DISTRICT, BONE BOLANGO REGENCY, GORONTALO PROVINCE, IN 2022 Abubakar, Fadlun; Yunus, Fitriah Ayu Magfirah; Hasili, Abdul Sulhadi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1195

Abstract

Generic drugs are medications with generic names, as defined by the Indonesian Pharmacopoeia and International Non-proprietary Names (INN) from the WHO, and they do not use trade names or manufacturer logos. Examples of these include amoxicillin and metformin. The public often perceives generic drugs to be inferior to patented drugs because of their relatively lower prices. The purpose of this study is to describe the knowledge level of the community about the use of generic drugs in Desa Tupa, Kecamatan Bulango Utara, Kabupaten Bone Bolango in 2022. This study employs a descriptive method using a quantitative approach. Data were collected through questionnaires that were distributed to 30 randomly selected respondents. A univariate analysis was conducted by creating frequency distributions to determine the community's awareness level regarding generic drugs. The survey results indicated that most residents of Desa Tupa have limited information about the use of generic drugs. The study concluded that, in terms of knowledge level about generic drugs, 30% of respondents had heard of generic drugs, 22% knew that generic drugs were named according to INN (International Non-proprietary Names), 11% understood that generic drugs are those that have expired patents, 9% recognize that generic drugs do not use brand names, and 28% are aware that generic drugs are more affordable than branded drugs.
Optimalisasi Penerapan Program Kesehatan dan Keselamatan Kerja (K3) di Laboratorium Kimia dan Mikrobiologi Poltekkes Kemenkes Gorontalo Jahja, Sitti Rhomlah; Hasili, Abdul Sulhadi; Faizah, Atyaf Umi; Yunus, Fitriah Ayu Magfirah
Jurnal Keselamatan Kesehatan Kerja dan Lingkungan Vol. 6 No. 1 (2025): Januari - Juni 2025
Publisher : Fakultas Kesehatan Masyarakat Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jk3l.6.1.94-107.2025

Abstract

Laboratorium pendidikan berperan sebagai fasilitas penunjang akademik, namun memiliki potensi bahaya yang dapat menyebabkan kecelakaan kerja. Penelitian ini bertujuan untuk mengevaluasi dan mengoptimalisasi pelaksanaan program K3 di Laboratorium Kimia dan Mikrobiologi Poltekkes Kemenkes Gorontalo. Penelitian ini dilakukan pada bulan Mei sampai Agustus 2024. Metode yang dilakukan yaitu deskriptif kuantitatif. Pengambilan sampel dilakukan pada pengguna laboratorium menggunakan metode purposive sampling dengan kriteria spesifik yang diwakili oleh sejumlah 300 responden. Teknik pengumpulan data secara triangulasi teknik melalui observasi kondisi laboratorium secara langsung, survey pada pengguna laboratorium, dan dokumentasi kondisi laboratorium. Hasilnya menunjukkan mayoritas responden memahami program K3, namun beberapa aspek perlu ditingkatkan, seperti konsistensi penggunaan APD, pemahaman fasilitas K3 dan alat tanggap darurat, serta kepatuhan terhadap prosedur pembuangan limbah kimia. Optimalisasi meliputi sosialisasi dan pelatihan rutin, penyusunan pedoman komprehensif, dan peningkatan kepatuhan terhadap standar keselamatan kerja untuk menciptakan lingkungan laboratorium yang aman.
Antibacterial Activity Test of Etanol Extract of Black Sea Cucumber (Holothuria atra) against the Bacteria Staphylococcus aureus and Escherichia coli Husain, Fadli; Padja, Tegar Abdiyanto; Slamet, Nangsih Sulastri; Nur, Moh. Usman; Yunus, Fitriah Ayu Magfirah; Abubakar, Fadlun; Polontalo, Febriyanti
JURNAL INFO KESEHATAN Vol 23 No 1 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss1.1337

Abstract

Black Sea cucumber (Holothuria atra) contain chemical compounds that has antibacterial activity. One of the bacteria that is pathogenic to humans and at risk of death are Staphylococcus aureus and Eschericia coli. The purpose of this study is to ascertain whether black sea cucumber ethanol extract in Pataomeme waters has antibacterial activity against the microorganisms E. coli and S. aureus. The type of research used is quantitative research with quasi laboratory experiments. Antibacterial activity test using disc diffusion method. Black Sea cucumber extract was made in 3 concentrations, consisted of 7.5%, 10% and 12.5%. The results showed that black sea cucumber extract has antibacterial activity seen through the inhibition zone formed. The maximum inhibition zone is at a concentration of 12.5% sea cucumber extract, which is 28.59 mm against S. aureus bacteria and 21.02 mm against E. coli bacteria. According to our results, sea cucumber may be a suitable marine source of antibacterial substances. To ascertain its potential use in other areas of medicine, more in vivo research must be conducted.
Co-Authors Abubakar, Fadlun Basri, Insyira Fadliana Basri, Rakhmadhana Fitraeni Daud, Rizka Puji Astuti Faizah, Atyaf Umi Febriyanti Polontalo Fihrina Mohamad Hasili, Abdul Sulhadi Husain, Fadli Imran, Arlan K Jahja, Sitti Rhomlah Nur, Moh. Usman Padja, Tegar Abdiyanto PRISCA SAFRIANI WICITA