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All Journal Tarumanagara Medical Journal Jurnal Kedokteran Meditek
Linus, Ariel
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Hubungan antara konsumsi protein dengan keparahan dermatitis atopik pada mahasiswa kedokteran Universitas Tarumanagara Angkatan 2020-2021 Linus, Ariel; Darmawan, Hari
Tarumanagara Medical Journal Vol. 5 No. 2 (2023): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v5i2.25215

Abstract

Dermatitis atopik (DA) memiliki karakteristik yang bisa dilihat secara klinis dengan adanya lesi eksim kronik rekuren, kulit kering, serta pruritus. Perbedaan data terkait konsumsi protein, di mana protein yang tinggi dapat menyebabkan DA namun kekurangan protein juga dapat menyebabkan DA, membuat studi ini perlu dilakukan dengan tujuan untuk mengetahui hubungan konsumsi protein dengan keparahan dermatitis atopik. Studi analitik observasional yang didesain secara cross-sectional dilakukan terhadap mahasiswa kedokteran Universitas Tarumanagara angkatan 2020 dan 2021. Responden dalam studi ini berjumlah 79 mahasiswa yang telah didiagnosis dermatitis atopic menggunakan serangkaian instrument. Pengambilan responden menggunakan teknik consecutive sampling. Konsumsi protein dinilai dengan Recommended Daily Allowance (RDA) protein. Pada studi didapatkan mayoritas mengalami dermatitis atopik ringan (65,8%) dan mengonsumsi protein di bawah batas yang dianjurkan, yaitu 5,6 g/kgBB/minggu (79,7%).  Sebanyak 38 (60,3%) orang dari 63 responden yang mengonsumsi protein di bawah batas anjuran mengalami dermatitis atopi ringan. Hal yang sama juga terjadi pada 14 (87,5%) orang dari 16 responden yang mengonsumsi protein ≥ 5,6 gram/kgBB/hari mengalami dermatitis ringan.  Secara statistik didapatkan hubungan yang signifikan antara konsumsi protein dengan keparahan dermatitis atopik (p-value = 0,04). Hasil studi memperlihatkan sesorang yang mengonsumsi protein kurang maupun berlebih lebih cenderung mengalami dermatitis atopik derajat ringan.
Kortikosteroid Oral Jangka Pendek sebagai Tata Laksana Psoriasis Vulgaris: Sebuah Laporan Kasus Linus, Ariel; Moniaga, Catharina Sagita; Sutedja, Gina Triana
Jurnal Kedokteran Meditek Vol 31 No 3 (2025): MEI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i3.3670

Abstract

Introduction: While oral corticosteroids are not included in the psoriasis systemic therapy algorithm, they are still utilized in certain cases because of their anti-inflammatory and immunosuppressive properties. This case report describes a case of psoriasis vulgaris treated with oral corticosteroids as replacement therapy for first-line drugs. Case Illustration: A 53-year-old male presented to Ciawi Regional Hospital with a complaint of a red, scaly rash that had been itchy on his back for a year, which was spreading to his entire body and worsening over the last 3 months. The physical examination revealed erythematous papules and plaques with thick, silver scales throughout his body. He was diagnosed with psoriasis vulgaris, with a Psoriasis Area Severity Index (PASI) score of 32.6. The patient utilized National Health Insurance, which did not cover the first-line drugs; therefore, he was prescribed oral methylprednisolone instead. After two weeks of medication, his clinical manifestations improved, resulting in a PASI score of 5.5. Discussion: The oral corticosteroid provided a significant improvement in skin lesions for this patient. This improvement may be due to its anti-inflammatory and immunosuppressive effects. Close monitoring after treatment is crucial, as flare-ups and side effects may occur after treatment with oral corticosteroids. Conclusion: The use of oral corticosteroids in the treatment of psoriasis vulgaris is an option when first-line drugs are not available, followed by post-treatment observation
Co-Authors Hari Darmawan Moniaga, Catharina Sagita Sutedja, Gina Triana