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All Journal Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Metamorfosa: Journal of Biological Science Open Access DRIVERset
Sajuni Widjaja
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Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Neuroscience Public Health

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PROFIL STATUS NUTRISI MASYARAKAT DI KAWASAN EKS LOKALISASI DOLLY PASCA PENUTUPAN LOKALISASI DOLLY Anita Dahliana; Dwi Martha Nur Aditya; Sajuni Widjaja; Katharina Merry Apriliani; Winnie Nirmala Santosa; Ardyan Prima Wardhana
Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Vol 5 No 3 (2023): December
Publisher : Fakultas Kedokteran Universitas Alkhairaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/ma.v5i3.153

Abstract

Kawasan lokalisasi Dolly, Putat Jaya sudah ditutup semenjak tahun 2014. Semenjak penutupannya, pemerintah kota Surabaya telah melakukan banyak program pemberdayaan untuk meningkatkan perekonomian masyarakat yang tinggal di lokalisasi Dolly. Status nutrisi berhubungan erat dengan tingkat ekonomi. Penelitian ini merupakan jenis penelitian observasional, desain cross sectional yang bertujuan mengetahui status nutrisi masyarakat yang tinggal di kawasan eks lokalisasi Dolly menggunakan data indeks massa tubuh pada masyarakat yang tinggal di kawasan eks lokalisasi Dolly dan masyarakat yang tinggal di kawasan non eks lokalisasi Dolly. Hasil uji statistik menggunakan Chi-Square Fisher’s Exact Test menunjukkan bahwa tidak terdapat perbedaan status nutrisi antara masyarakat yang tinggal di kawasan eks Dolly dibandingkan Masyarakat yang tinggal di Kawasan non eks Dolly. Hal ini diduga dikarenakan adanya perbaikan kondisi ekonomi dan dikarenakan berhasilnya program pemberdayaan yang telah dilakukan oleh pemerintah kota Surabaya.
Uji Efektivitas Antibiotik Ekstrak Etanol Daun Kayu Manis (Cinnamomum burmannii) terhadap Pertumbuhan Bakteri Staphylococcus sureus dan Escherichia coli secara In Vitro Sang Ayu Bulan Dirga Pradnyani; Risma Ikawaty; Sajuni Widjaja; Sang Ketut Sudirga
Metamorfosa: Journal of Biological Sciences Vol. 13 No. 1 (2026)
Publisher : Program Magister Ilmu Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa. 2026.v13.i01.p3

Abstract

Bacterial infections caused by S. aureus and E. coli remain a major global health problem. Irrational antibiotic use has accelerated antimicrobial resistance, prompting the search for alternative antibacterial agents derived from natural products. Cinnamon leaves (Cinnamomum burmannii) contain various secondary metabolites with potential antibacterial activity. This study aimed to evaluate the antibacterial activity of ethanolic cinnamon leaf extract against S. aureus and E. coli in vitro and to determine the most effective extract concentration. This laboratory-based true experimental study employed a post-test only control group design. Cinnamon leaf extract was prepared by maceration using 96% ethanol. Antibacterial activity was assessed using the well diffusion method on Mueller Hinton Agar at extract concentrations of 25%, 50%, 75%, and 100%. Ciprofloxacin served as the positive control, while 96% ethanol was used as the negative control. Phytochemical screening and antioxidant activity testing (DPPH method) were also performed. Data were analyzed using One-Way ANOVA followed by Duncan post-hoc test. Result : Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, saponins, and phenolic compounds, with phenols as the dominant constituents. The extract exhibited moderate antioxidant activity based on IC₅₀ values. Antibacterial testing demonstrated that ethanolic cinnamon leaf extract inhibited the growth of both S. aureus and E. coli, with inhibition zones increasing in a concentration-dependent manner. The 75% concentration demonstrated optimal inhibitory activity, with no statistically significant difference compared to the 100% concentration (p > 0.05). Ethanolic cinnamon leaf extract (Cinnamomum burmannii) shows promising antibacterial activity against S. aureus and E. coli in vitro, indicating its potential as a natural antibacterial agent.
Uji Efektivitas Antibiotik Ekstrak Etanol Daun Kayu Manis (Cinnamomum burmannii) terhadap Pertumbuhan Bakteri Staphylococcus sureus dan Escherichia coli secara In Vitro Sang Ayu Bulan Dirga Pradnyani; Risma Ikawaty; Sajuni Widjaja; Sang Ketut Sudirga
Metamorfosa: Journal of Biological Sciences Vol. 13 No. 1 (2026)
Publisher : Program Magister Ilmu Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa. 2026.v13.i01.p3

Abstract

Bacterial infections caused by S. aureus and E. coli remain a major global health problem. Irrational antibiotic use has accelerated antimicrobial resistance, prompting the search for alternative antibacterial agents derived from natural products. Cinnamon leaves (Cinnamomum burmannii) contain various secondary metabolites with potential antibacterial activity. This study aimed to evaluate the antibacterial activity of ethanolic cinnamon leaf extract against S. aureus and E. coli in vitro and to determine the most effective extract concentration. This laboratory-based true experimental study employed a post-test only control group design. Cinnamon leaf extract was prepared by maceration using 96% ethanol. Antibacterial activity was assessed using the well diffusion method on Mueller Hinton Agar at extract concentrations of 25%, 50%, 75%, and 100%. Ciprofloxacin served as the positive control, while 96% ethanol was used as the negative control. Phytochemical screening and antioxidant activity testing (DPPH method) were also performed. Data were analyzed using One-Way ANOVA followed by Duncan post-hoc test. Result : Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, saponins, and phenolic compounds, with phenols as the dominant constituents. The extract exhibited moderate antioxidant activity based on IC₅₀ values. Antibacterial testing demonstrated that ethanolic cinnamon leaf extract inhibited the growth of both S. aureus and E. coli, with inhibition zones increasing in a concentration-dependent manner. The 75% concentration demonstrated optimal inhibitory activity, with no statistically significant difference compared to the 100% concentration (p > 0.05). Ethanolic cinnamon leaf extract (Cinnamomum burmannii) shows promising antibacterial activity against S. aureus and E. coli in vitro, indicating its potential as a natural antibacterial agent.
Co-Authors Anita Dahliana Ardyan Prima Wardhana Dwi Martha Nur Aditya Katharina Merry Apriliani Risma Ikawaty Sang Ayu Bulan Dirga Pradnyani SANG KETUT SUDIRGA Winnie Nirmala Santosa