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Current Technology in Hip Replacement Phatama, Krisna Yuarno
The Hip and Knee Journal Vol 5, No 2 (2024): August
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46355/hipknee.v5i2.181

Abstract

Hip replacement, also known as total hip arthroplasty (THA), is widely regarded as an incredibly effective surgical procedure, often hailed as a ground-breaking achievement in medicine.1 The initial development of total hip replacement dates back to 1938 when Wiles made significant progress.2 However, it wasn't until the 1960s that this procedure gained widespread recognition and popularity. Sir John Charnley's introduction of "low-friction arthroplasty" revolutionized the treatment of arthritic joints.1 Over time, significant progress has been made in THA's design, materials, and surgical techniques, significantly enhancing patient satisfaction, minimizing surgical complications, and improving clinical outcomes. Patients' expectations regarding life after total hip arthroplasty (THA) have significantly shifted. They prioritize long-term survival and the various aspects of maintaining a good quality of life. They have a strong desire to pursue their professional and personal interests, which require a high level of physical activity.3The initial technological advancement in hip replacement surgery was the introduction of Minimally Invasive Surgery (MIS), which reduced the surgical footprint. MIS techniques involve smaller incisions and less soft tissue disruption, reducing postoperative pain and faster recovery times. This approach contrasts with traditional open surgery, which typically requires larger incisions and more extensive muscle dissection. MIS procedures have been proven to enhance cosmetic outcomes, minimize hospital stays, and accelerate rehabilitation.4,5A growing focus has recently been on customizing joint replacement procedures to suit individual patients rather than relying on a generic and uniform approach. A computer-assisted surgery (CAS) and robotic-assisted surgery represent significant technological leaps in hip replacement. CAS utilizes preoperative imaging and intraoperative navigation to enhance the precision of implant placement. CAS improves the alignment of the acetabular and femoral components, thereby reducing the risk of dislocation and improving functional outcomes.6 Robotic-assisted systems, such as the MAKO robotic arm, have refined this precision. These systems allow for patient-specific surgical planning and real-time adjustments during the procedure. Studies have shown that robotic-assisted surgery results in superior implant positioning and reduced variability in component placement.6,7 The integration of these technologies into clinical practice represents a significant advancement in achieving optimal surgical outcomes.Another enhancement in hip replacement surgery is the development of advanced biomaterials, which have been pivotal in extending the longevity of hip implants. Traditional metal-on-polyethylene bearings, while effective, are prone to wear and osteolysis over time. Recent advancements have introduced ceramic-on-ceramic and ceramic-on-polyethylene bearings, which exhibit lower wear rates and higher biocompatibility.8 Ceramic materials, being more complex and smoother than metals, significantly reduce friction and wear particles, enhancing the implant's lifespan. Highly porous metals, such as trabecular metal, have also been developed to improve osseointegration. These materials mimic the trabecular structure of natural bone, promoting biological fixation and reducing the reliance on bone cement. The benefits of trabecular metal are in providing a stable and durable implant-bone interface, which is crucial for the long-term success of hip replacements.9Enhanced Recovery After Surgery (ERAS) protocols represent a multidisciplinary approach to optimizing perioperative care. These protocols focus on preoperative education, optimized pain management, and early mobilization. ERAS protocols have been shown to reduce hospital stays, decrease complications, and improve overall patient outcomes in hip replacement surgery. Implementing ERAS has led to a paradigm shift in postoperative care, emphasizing patient-centered approaches and evidence-based practices.10Despite these advancements, challenges remain in hip replacement surgery. Implant longevity in younger, more active patients continues to be a concern. Additionally, periprosthetic joint infections (PJIs) pose a significant risk to implant success. Current researHip replacement, also known as total hip arthroplasty (THA), is widely regarded as an incredibly effective surgical procedure, often hailed as a ground-breaking achievement in medicine.1 The initial development of total hip replacement dates back to 1938 when Wiles made significant progress.2 However, it wasn't until the 1960s that this procedure gained widespread recognition and popularity. Sir John Charnley's introduction of "low-friction arthroplasty" revolutionized the treatment of arthritic joints.1 Over time, significant progress has been made in THA's design, materials, and surgical techniques, significantly enhancing patient satisfaction, minimizing surgical complications, and improving clinical outcomes. Patients' expectations regarding life after total hip arthroplasty (THA) have significantly shifted. They prioritize long-term survival and the various aspects of maintaining a good quality of life. They have a strong desire to pursue their professional and personal interests, which require a high level of physical activity.3The initial technological advancement in hip replacement surgery was the introduction of Minimally Invasive Surgery (MIS), which reduced the surgical footprint. MIS techniques involve smaller incisions and less soft tissue disruption, reducing postoperative pain and faster recovery times. This approach contrasts with traditional open surgery, which typically requires larger incisions and more extensive muscle dissection. MIS procedures have been proven to enhance cosmetic outcomes, minimize hospital stays, and accelerate rehabilitation.4,5A growing focus has recently been on customizing joint replacement procedures to suit individual patients rather than relying on a generic and uniform approach. A computer-assisted surgery (CAS) and robotic-assisted surgery represent significant technological leaps in hip replacement. CAS utilizes preoperative imaging and intraoperative navigation to enhance the precision of implant placement. CAS improves the alignment of the acetabular and femoral components, thereby reducing the risk of dislocation and improving functional outcomes.6 Robotic-assisted systems, such as the MAKO robotic arm, have refined this precision. These systems allow for patient-specific surgical planning and real-time adjustments during the procedure. Studies have shown that robotic-assisted surgery results in superior implant positioning and reduced variability in component placement.6,7 The integration of these technologies into clinical practice represents a significant advancement in achieving optimal surgical outcomes.Another enhancement in hip replacement surgery is the development of advanced biomaterials, which have been pivotal in extending the longevity of hip implants. Traditional metal-on-polyethylene bearings, while effective, are prone to wear and osteolysis over time. Recent advancements have introduced ceramic-on-ceramic and ceramic-on-polyethylene bearings, which exhibit lower wear rates and higher biocompatibility.8 Ceramic materials, being more complex and smoother than metals, significantly reduce friction and wear particles, enhancing the implant's lifespan. Highly porous metals, such as trabecular metal, have also been developed to improve osseointegration. These materials mimic the trabecular structure of natural bone, promoting biological fixation and reducing the reliance on bone cement. The benefits of trabecular metal are in providing a stable and durable implant-bone interface, which is crucial for the long-term success of hip replacements.9Enhanced Recovery After Surgery (ERAS) protocols represent a multidisciplinary approach to optimizing perioperative care. These protocols focus on preoperative education, optimized pain management, and early mobilization. ERAS protocols have been shown to reduce hospital stays, decrease complications, and improve overall patient outcomes in hip replacement surgery. Implementing ERAS has led to a paradigm shift in postoperative care, emphasizing patient-centered approaches and evidence-based practices.10Despite these advancements, challenges remain in hip replacement surgery. Implant longevity in younger, more active patients continues to be a concern. Additionally, periprosthetic joint infections (PJIs) pose a significant risk to implant success. Current research explores antibacterial coatings and systemic antibiotic regimens to address PJIs.11 Integrating artificial intelligence (AI) and machine learning (ML) into hip replacement surgery offers promising future directions. AI-driven predictive analytics can assist in preoperative planning by identifying patients at higher risk of complications and customizing treatment plans. Furthermore, ML algorithms can analyze postoperative data to monitor patient recovery and predict long-term outcomes.12ch explores antibacterial coatings and systemic antibiotic regimens to address PJIs.11 Integrating artificial intelligence (AI) and machine learning (ML) into hip replacement surgery offers promising future directions. AI-driven predictive analytics can assist in preoperative planning by identifying patients at higher risk of complications and customizing treatment plans. Furthermore, ML algorithms can analyze postoperative data to monitor patient recovery and predict long-term outcomes.12
Fight against Periprosthetic Joint Infection Phatama, Krisna Yuarno; Santoso, Asep; Rhatomy, Sholahuddin
The Hip and Knee Journal Vol 4, No 1 (2023): February
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.523 KB) | DOI: 10.46355/hipknee.v4i1.151

Abstract

Golden Connection Between Stem Cells and Orthopedic Services Rhatomy,MD, Sholahuddin; Santoso, Asep; Phatama, Krisna Yuarno; Budhiparama, Nicolaas C.
The Hip and Knee Journal Vol 3, No 2 (2022): August
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.721 KB) | DOI: 10.46355/hipknee.v3i2.132

Abstract

Utilization of stem cells in orthopedics has increased dramatically. Consequently, stem cells were discovered to have many roles. Some researchers have used them for regenerative medicine, while some have discovered them as a natural source of immune modulators. Currently, there are several research teams studying the translational potential of stem cells, while clinicians have begun treating patients with orthopedic problems (1).Over the past fifteen years, orthopedic surgeons have prioritized Mesenchymal Stem Cell (MCSs) treatment. Several animal experiments have had favorable results, and there is rising concern over their use in human trials. In these clinical studies, stem cell operations were intended to promote fracture healing and cure nonunion, regenerate articular cartilage in degenerated joints, repair ligament or tendon injuries, and replace degenerative spinal disks (1,2).In past research, stem cells have been used for bone tissue regeneration. Bone tissue engineering presents an alternative treatment that may produce a micromilieu with osteogenic, osteoinductive, and osteoconductive properties. In recent studies, researchers have devised methods for combining MSCs with three-dimensional biodegradable polymeric scaffolds. In addition, Udehiya et al. found that the use of hydroxyapatite scaffolds in conjunction with Bone Marrow-MSCs (BM-MSC) accelerates and enhances the healing of bone segmental defects in a rabbit model compared to the use of hydroxyapatite scaffolds alone. Muwan Chen and colleagues discovered that human BM-MSC combined with hyaluronic acid and b-Tri calcium phosphate-coated polymeric scaffold stimulated osteogenic differentiation, cellular proliferation, and reorganization of the cellular matrix in vitro (1–3).Since 2010, stem cells have undergone a paradigm shift where previously stem cells can differentiate and heal injured organs. This stem cell misunderstanding has led some practitioners in the United States and around the world to advertise the availability of stem cell treatments, e.g., MSC can heal blindness, make paralyzed people walk, and makes old tissue young again. In further studies, it was found that at the site of disease, MSCs rarely or never differentiated into tissue at that location, but they do secrete bioactive factors such as growth factors and their therapeutic effects can be analyzed as a site-specific clinical outcome parameter (2–4).
High Tibial Osteotomy for knee joint preservation: “Old but Gold”! Santoso, Asep; Phatama, Krisna Yuarno; Rhatomy, Sholahuddin; Budhiparama, Nicolaas Cyrillus
The Hip and Knee Journal Vol 4, No 2 (2023): August
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46355/hipknee.v4i2.154

Abstract

One of the most common chronic diseases affecting the elderly is knee osteoarthritis (OA) that significantly impairs the activity of the daily living. Change of mechanical axis of the knee causes impairment on the three compartments of knee. If the medial compartment is affected, it will cause varus knee deformity, whereas, involvement of lateral compartment will result in valgus knee deformity. Deformities of angular and/or rotational nature can be corrected using the knee osteotomy technique, consequently realigning the bone axis.The osteotomy technique has been developed for centuries. Current growing interest in developing minimally invasive techniques for high tibial osteotomy (HTO) using smaller incisions, arthroscopy-assisted osteotomy, patients specific instrumentation (PSI) and computer-guided navigations systems. These techniques aim to reduce surgical trauma, minimize scarring, and facilitate faster recovery.
Biofilms: Microbial Communities and Their Crucial Impact on Healthcare Rhatomy,MD, Sholahuddin; Santoso, Asep; Phatama, Krisna Yuarno; Budhiparama, Nicolaas C.
The Hip and Knee Journal Vol 5, No 1 (2024): February
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46355/hipknee.v5i1.157

Abstract

Pengaruh Nitrogen Cair terhadap Morfologi dan Jumlah Fibroblas pada Tendon Patela Tikus Wistar Jantan Isma, Satria Pandu Persada; Norahmawati, Eviana; Irsan, Istan Irmansyah; Asmiragani, Syaifullah; Phatama, Krisna Yuarno; Adiwignyo, Dandy Drestanto; Pratama, Yudit Alfa`
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Cryoablation with liquid nitrogen has shown promise in treating bone sarcomas, but its effect on fibroblast morphology and viability in ligament tissues remains unclear. This study aims to evaluate the impact of liquid nitrogen on fibroblasts in the patellar tendon ligament of male Wistar rats. Methods: This experimental study utilized 28 male Wistar rats (6 months old, 300-400 grams) that were randomly divided into four groups. The control group was not exposed to liquid nitrogen, while the experimental groups were exposed to liquid nitrogen for 1, 5, and 10 minutes. After a 7-day acclimatization, the rats were exposed to liquid nitrogen and euthanized. The patellar tendon ligaments were collected for histological analysis, stained with Hematoxylin-Eosin, and examined under a microscope. Statistical analysis was performed using One-Way ANOVA, followed by Tukey post hoc tests to determine the significant differences between the exposure times. Results: Significant changes were observed in fibroblast morphology and count with increasing exposure times. One-way ANOVA analysis revealed significant differences (p < 0.001) in fibroblast count and morphological alterations across exposure groups. Tukey post hoc tests revealed that 10-minute exposure resulted in substantial reductions in fibroblast count and viability, accompanied by progressive morphological changes as exposure time increased. Discussion: Liquid nitrogen exposure significantly impacts fibroblast cells, with longer exposure times causing more severe cellular damage. The exposure duration should be carefully controlled in cryotherapy to optimize therapeutic benefits. Conclusion: Exposure to liquid nitrogen adversely affects fibroblast cells in the patellar tendon ligament, with prolonged exposure resulting in decreased cesll viability and morphological changes.