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All Journal MNJ (Malang Neurology Journal) Jurnal Biomedika dan Kesehatan Malang Respiratory Journal Journal of Community Health and Preventive Medicine (JOCHAPM)
Asmiragani, Syaifullah
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Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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NEUROLOGICAL MANIFESTATION ON HOSPITALIZED PATIENT WITH PROBABLE COVID-19 IN SAIFUL ANWAR HOSPITAL INDONESIA (SERIAL CASES) Munir, Badrul; Rianawati, Sri Budhi; Kurniawan, Shahdevi Nandar; Santoso, Widodo Mardi; Arisetijono, Eko; Candradikusuma, Didi; Heri, Sutanto; Chozin, Iin Noor; Dwi, Pratiwi Suryanti; Astuti, Tri Wahju; Asmiragani, Syaifullah
MNJ (Malang Neurology Journal) Vol. 6 No. 2 (2020): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

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Abstract

Background: Coronavirus disease 2019 (Covid-19) caused by SARS-Cov-2 had been spreading worldwide including Indonesia, but In Indonesia, it was difficult to diagnose confirmation Covid-19 by Polymerase Change Reaction (PCR). and in clinical practice to treat covid-19,  Indonesia Health Ministry use term probable covid-19 for patients under observation Covid-19, but study for neurological manifestation on  probable Covid-19 is very lacking.Objective: Knowing the neurological manifestation of patient probable Covid-19.Methods: Observational study from Covid-19 medical record and neuro-Covid-19 medical record of all probable Covid-19 hospitalized in the isolation ward of Saiful Anwar Hospital (RSSA) Malang since March-May, 2020 (3 months). Probable Covid-19 criteria were given by Covid-19 task force team based on Health Minister Indonesia criteria. This criterion was based on clinical manifestation (severe upper respiratory symptoms, or mild-severe pneumonia), radiologic examination (lung infiltrate and or chest CT scan), and laboratory examination. Neurological manifestation is based on clinical symptom appeared while patient hospitalized, supported with radiologic and laboratory data which was supervised by neurologist or neurologist resident. All data was inputted to neuro-Covid-19 e-registry on the smartphone application, sent periodically to the data center in Neurology Department RSSA Malang.Results: A hundred and fourteen probable Covid-19 was registered with mean age 34,5 year old and mostly at the young age of 20-50 years (38%). The neurological manifestation was observed in 4 patients (3,4% from all possible Covid-19 patients) with thrombotic stroke as the most common manifestation (50%), followed by myelum tumor (25%) and hypoxia encephalopathy (25%). Stroke patients in probable Covid-19 had old age (72 and 82 years) accompanied by several comorbid such as hypertension, DM and CVA history and Covid symptoms of cough, shortness of breath and fever. Hemiparesis was found improved with aspirin and neurotropic therapy. Patient with myelum tumor had a covid symptom of shortness of breath, cough, and fever with UMN tetraparesis. Previous MRI examination results suspected meningioma. The patient died while hospitalized. Patients with hypoxia encephalopathy admitted with decreased consciousness due to shortness of breath with acidosis respiratory symptoms (pH 7,22 ). This condition improved after oxygenation without focal neurologic deficit.Conclusion: Neurological manifestation in probable Covid-19 was 3,4% of all patients. The most common diagnosis was a thrombotic stroke, followed by myelum tumor, hypoxia encephalopathy, and mortality rate is 25%.
THE DIFFERENCES IN COMPLETENESS AND TIMELINESS OF ELECTRONIC MEDICAL RECORD DOCUMENTATION IN NURSING WARDS: PERSPECTIVES FROM SURGICAL AND NON-SURGICAL DOCTORS Asmiragani, Syaifullah; Sri Andarini; Viera Wardhani
Journal of Community Health and Preventive Medicine Vol. 5 No. Issue Supplement 1 (2025): JOCHAPM Vol. 5, Issue Supplement 1, March 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

The 2023 Quality Committee Report of Hospital X revealed lower levels of completeness and timeliness in the surgical ward, especially in the initial assessment, initial medical plan, and patient progress notes. Regarding this, the present study aims to analyze problematic Electronic Medical Records (EMR) components and the factors causing incompleteness and delay in data entry in surgeons and non-surgeons. This cross-sectional study was conducted by using 362 inpatient EMRs to analyze four key components, namely initial assessment, initial medical plan, Integrated Patient Progress Note (IPPN), and medical resume. Besides, 293 doctors completed questionnaires assessing their understanding of EMR-related regulations and their data entry timing for the four components. Completeness and timeliness analysis was performed using Chi-Square, while understanding of regulations and entry time was analyzed using Mann-Whitney. The findings indicated that non-surgeons showed higher completeness and timeliness in the initial assessment, medical resume, and CPPT (p<0.05), while surgeons excelled in the initial diagnostic plan in the initial medical plan (p<0.05). There was no difference in understanding of regulations, but non-surgeons took longer to enter data on assessment and initial medical plan (p<0.05). Finally, contributing factors include EMR technology, physician workflow, and physician interaction time with the EMR.
Three Tuberculosis Spondylitis Patients With Resistant Rifampicin From the Transpedicular Debridement Surgery Network Widowati, Yenny; Jane, Yani; Pratiwi, Suryanti Dwi; Asmiragani, Syaifullah
Malang Respiratory Journal Vol. 3 No. 1 (2021): Vol. 3 No. 1
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2021.003.01.6

Abstract

Background: TB spondylitis is a disease that can cause neurological disorders, ranging from 1-2% of the total cases of tuberculosis where the most frequent infection is the spine followed by other large joints such as hips, knees and shoulders. The increase in TB spondylitis associated with MDR TB in 2015 showed 52% or about 32,000 incidences globally.Collaboration of individual alloy MDR TB therapy with surgery in TB spondylitis can reduce patient mortality and morbidity.Case: We report three cases of patients in 2017-2018 in Dr. Saiful Anwar with complaints of back pain and lumps in the back, from the results of anamnesa, physical examination and supporting examination of patients diagnosed with TB spondylitis, patients were given medical management, operative and rehabilitation.Conclusion: This case is interesting because from the results of Molecular Rapid Tests whose samples were obtained from a biopsy of the transpendicular debridement surgery tissue obtained the results of Resistant Rifampicin, all three patients received individualized OAT treatment, the development of the conditions of the three patients improved and quality of life improved.
Pengaruh Nitrogen Cair terhadap Morfologi dan Jumlah Fibroblas pada Tendon Patela Tikus Wistar Jantan Isma, Satria Pandu Persada; Norahmawati, Eviana; Irsan, Istan Irmansyah; Asmiragani, Syaifullah; Phatama, Krisna Yuarno; Adiwignyo, Dandy Drestanto; Pratama, Yudit Alfa`
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2025.v8.308-316

Abstract

Background Cryoablation with liquid nitrogen has shown promise in treating bone sarcomas, but its effects on fibroblast morphology and viability in ligament tissue remain unclear. This study aims to evaluate the effects of liquid nitrogen on fibroblasts in the patellar tendon ligament of male Wistar rats. Methods This experimental study used 24 male Wistar rats (6 months old, 300-400 grams), randomly divided into four groups. The control group was not exposed to liquid nitrogen, while the experimental groups were exposed for 1, 5, and 10 minutes, respectively. After 7 days of acclimatization, the rats were exposed to liquid nitrogen and then euthanized. The patellar tendon ligaments were collected for histological analysis, stained with Hematoxylin-Eosin, and examined under a microscope. Statistical analysis was performed using One-Way ANOVA, followed by Tukey post hoc tests to determine significant differences among exposure times. Results Significant changes in fibroblast morphology and count were observed with increasing exposure time. One-way ANOVA revealed significant differences (p < 0.001) in fibroblast count and morphological alterations across exposure groups. Tukey post hoc tests showed that a 10-minute exposure resulted in substantial reductions in fibroblast count and viability, accompanied by progressive morphological changes as exposure time increased. Discussion Exposure to liquid nitrogen significantly affects fibroblast cells, and longer exposure times lead to more severe cellular damage. Exposure duration should be carefully controlled during cryotherapy to optimize therapeutic benefits. Conclusions Exposure to liquid nitrogen adversely affects fibroblast cells in the patellar tendon ligament, with prolonged exposure resulting in decreased cell viability and morphological changes.
Co-Authors Adiwignyo, Dandy Drestanto Badrul Munir, Badrul Chozin, Iin Noor Didi Candradikusuma Dwi, Pratiwi Suryanti Eko Arisetijono Eviana Norahmawati Heri, Sutanto Irsan, Istan Irmansyah Phatama, Krisna Yuarno Pratama, Yudit Alfa` Pratiwi, Suryanti Dwi Satria Pandu Persada Isma Shahdevi Nandar Kurniawan, Shahdevi Nandar Sri Andarini Sri Budhi Rianawati, Sri Budhi Tri Wahju Astuti, Tri Wahju Viera Wardhani Widodo Mardi Santoso, Widodo Mardi Widowati, Yenny Yani Jane