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All Journal Chemistry Indonesian Journal of Chemical Research Urecol Journal. Part E: Engineering Prosiding University Research Colloquium
Vaira, Tischa
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Engineering Environmental Science Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology

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Design of Information Systems in Web-Based Medicine Ordering and Procurement Vaira, Tischa; Rohmah, Alfiyatu; Zaeniyah, Siti; Pribadi, Prasojo; Santoso, Setiyo Budi
Urecol Journal. Part E: Engineering Vol. 3 No. 1 (2023): January-June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/uje.255

Abstract

The drug distribution process determines the sustainability of drug stocks in pharmaceutical services. It is hoped that the design of an information system for drug procurement and ordering can make the distribution process more effective and efficient. While information systems for drug procurement and ordering exist, they are typically designed for individual distributors. This research aims to design an information system by displaying flowcharts that map the drug procurement and ordering process, and by developing user interfaces that facilitate interaction with the system. The research was carried out through a Literature Review. Reference searches were conducted using the Google Scholar search engine. The keywords used in the keyword search were "pharmaceutical wholesalers AND information system design AND drug procurement" and the references selected were within the last 10 years. The information system design was implemented by creating flowchart diagrams using draw.io software and developing user interface designs using Microsoft Office PowerPoint 2019. The drug procurement and ordering information system can be accessed by PBFs as distributors and pharmacists as consumers. The information system designed is included in the e-Health Commerce Application type, which aims to facilitate the payment process and reduce costs incurred by the health environment. The designed information system can create a more efficient drug distribution process.
Comprehensive In silico Analysis of Antibacterial Compounds in n-Hexane Fraction from Jeruju Leaf (Acanthus ilicifolius) Wardani, Arief Kusuma; Haresmita, Perdana Priya; Alda, Mahkota; Vaira, Tischa
Indonesian Journal of Chemical Research Vol 11 No 3 (2024): Edition for January 2024
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2024.11-ari

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In an emergency, to identify the most promising Hesperidin, Kaempferol-3,4'-di-O-methyl ether (Ermanin); Myricetin-3-glucoside, Peonidine 3-(4’-arabinosylglucoside); Quercetin 3-(2G-rhamnosylrutinoside); and Rhamnetin 3-mannosyl-(1–2)-alloside as a lead compound from Jeruju to develop new drugs from flavonoid analog. The active compound's structure is derived from the PubChem database and improves the stability through ChemDraw v19. The Protein Data Bank website identified the protein macromolecule with PDB code 3VSL. Redocking was performed to ensure validation of 3VSL. The docking method was carried out using the IGEMDOCK software version v2.1. Also, the chimera-1.13.1 program is used to know the interaction profile. The web server pkCSM and Protox II online tool were used to determine the toxicity. 3,7,11,15-tetramethyl-2-hexadecen-1-ol is the juju leaf chemical with the most promise as an antibacterial and the one that shows the maximum binding affinity when taking into account toxicity.
Exploring the Role of Overall Survival in Chemotherapy Protocol: A Literatur Review: Telaah Pustaka Penilaian Overall Survival Sebagai Parameter Klinis Tata Terapi Kanker Pratiwi, Selma Septi; Khamdun, Ibnu; Fitrianasari, Resma Dwi Putri; Vaira, Tischa; Riska, R; Santoso, Setiyo Budi
Prosiding University Research Colloquium Proceeding of The 18th University Research Colloquium 2023: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Overall survival (OS) assesses the patient's survival rate after undergoing therapy. The evaluation of OS becomes a reliable clinical endpoint for assessing the malignancy response to chemotherapy intervention. Here in, we review a number of publications on PCR data in various chemotherapy protocols for different types of cancer. The literature review involves nine scientific articles that meet the inclusion criteria provided by the PubMed database. Our findings present the performance of chemotherapy protocols with the highest OS values for each type of cancer, including: Non-Small Cell Lung Cancer Metastasis (Durvalumab plus Tremelimumab-31.2), Non-Metastatic Non-Small Cell Lung Cancer (Nivolumab-30.8), Small Cell Lung Cancer (Carboplatin and Etoposide-13.2), Breast Cancer (Ribociclib plus Fulvestrant-67.6), Metastatic Breast Cancer (Olaparib-18.9), Metastatic Colorectal Cancer (Trifluridine/tipiracil-13.1), Liver Cancer (SBRT 44.1). This article reviews a number of publications on PCR data in various chemotherapy protocols for different types of cancer.
Co-Authors Alda, Mahkota Fitrianasari, Resma Dwi Putri Khamdun, Ibnu Perdana Priya Haresmita, Perdana Priya Prasojo Pribadi Pratiwi, Selma Septi Riska, R Rohmah, Alfiyatu Santoso, Setiyo Budi Wardani, Arief Kusuma Zaeniyah, Siti