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Effectiveness of banana leaves extract (Musa paradisiaca L.) for wound healing Putra, Dimas Ariandi Candra; Lutfiyati, Heni; Pribadi, Prasojo
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Banana leaves (Musa Paradisiaca, L.) has not been widely used in the treatment purpose of this study was to examine the wound healing activity of the gel of banana leaves (Musa paradiasiaca L.) and determine the most effective concentration for wound healing.Target research is to provide natural wound treatment alternatives. The method used is eksperimental.Prosedur research study began with the identification of a banana leaf, banana leaf extraction, formulation of banana leaf extract gel with a concentration of 1%, 5%, 10% and testing to the test animals were harmed .Animal test are grouped into 5 groups the negative control group (base gel), a positive control (bioplacenton), and 3 groups treatment. Measuring ofÂ diameter wound on day-1 through day 7. The observation was tested by using ANOVA and Post Hoc Tukey HSD. ANOVA test results showed a significant difference between the mean percentage of wound healing all groups Treatment .The result ofÂ Post hoc Tukey HSD at the 95% confidence level showed significant differences in the negative control group when compared to the positive control group and the treatment group gel 5% and 10% .It indicates that the positive control, gel 5% and 10% have a wound healing effect. Positive control group compared with the group treated gel 5% and 10% showed significant differences that the average value of the percentage of wound healing is higher than the positive control treatment group. It means the difference meant that the positive control has better activity. While the group gel 5% when compared with the 10% gel group no significant difference in this case means the group gel 5% with 10% having a comparable effectiveness of wound healing.

Formulasi dan evaluasi granul effervescent ekstrak daun binahong (Anredera cordifolia (Tenore) Steen.) Rahmawati, Indah Fortuna; Pribadi, Prasojo; Hidayat, Imron Wahyu
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The purpose of this research are to find out whether the formulation of effervescent granules from binahong leaves extract has met the standards for effervescent granules and determine the best formulation of effervescent granules. This research is descriptive experimental with data collection from evaluation of effervescent granules. To be able to make effervescent granules, extraction of binahong leaves must be made first. The extracts resulted from a maseration method with 70% ethanol. The effervescent granules formulation were made by 3 design based on their concentration F1 7.4%; F2 14.8%; and F3 22.2%. Effervescent granules of binahong leaves extract are prepared by using wet granulation method. Several physical tests were carried out on the results of effervescent granules of binahong leaves, including organoleptic test, moisture content test, pour volume test, volume of shringkage test, flow capacity test, dispersion test, and pH. The test results showed that all the effervescent granules of binahong leaves (Anredera cordifolia (Tenore) Steen.) have met the standard requirements as good granules. The third formula became the best formulation, With the best value in moisture content test, volume of shringkage test, flow capacity test, and pH.

APLIKASI PLASMA DINGIN UNTUK PERAWATAN LUKA NASRUDIN, NASRUDIN; PRIBADI, PRASOJO
Jurnal Keperawatan Muhammadiyah Vol 1, No 1 (2016): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.065 KB)

Objective: This study aims to determine the effect of cold plasma treatment for 7 days on wound healing in female Sprague Dawley ratsMethods: In studies using an experimental design that is 15 test animals were divided into three groups , namely positive control ( povidone iodine ) , positive control ( no treatment ) , cold plasma treatmentResults: wound healing descriptive operates on cold plasma treatment group there is an increased effectiveness of the wound, operating while statistics can be inferred no difference significant wound healing effectiveness cold plasma treatment between the negative controlConclusion: Aapplication of cold plasma had no effect wound healing

PEMANFAATAN PERASAN BUAH KEPEL (Stelechocarpus burahol (Blume) Hook & Thomson) SEBAGAI ANTISEPTIK LUKA Pribadi, Prasojo; Latifah, Elmiawati; Rohmayanti, Rohmayanti
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Fruit of kepel known contain of saponin and flavonoid, fruit of kepel is a plant that hasantibacterial and antiinflamation activity. This research purposed for made juice of fruit kepeland test of open wound healing process activity. Juice of fruit kepel is made with variety ofconcentration, which 20%, 40%, 60%, and 80%. Negative control used aquadest and positivecontrol used BetadineÂ® (Povidon Iodine). This type of research is experimental research,procedure start from the preparation of test materials, first identifying plants, then make fruitjuice of kepel and divide into several concentration, followed by grouping into six group of testanimals. All quantitative data were statistically analyzed using Anaylsis of Variance (Anova)and continued with Tukey Test, The lowest activity on the negative control and increase on thegroup of juice with concentration 20%, 40%, 80%, and 60%, higher activity on the positivecontrol. With wound healing broad parameters result that the group fruit juice of kepelconcentration 60% and 80% showed the statistically analyzed was more significant (p<0.05) 178 PharmaÒ«iana, Vol. 4, No. 2, 2014: 177-183than the negative control. So it can be taken conclusion that fruit juice of kepel concentration60% and 80% having wound healing activity.

Antecedents of willingness to provide pharmaceutical services for mental illness individuals Nesya Jeihan Daniswara; Setiyo Budi Santoso; Prasojo Pribadi
International Journal of Public Health Science (IJPHS) Vol 11, No 1: March 2022
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v11i1.20931

Pharmacists play a role in providing health care for mental illness patients such as medication management, providing drug information, medication counseling, and facilitating treatment adherence strategies. This study aimed to determine the effect of stigma, attitude and belief on the willingness to provide pharmaceutival services for mental illness individuals. This study design is a quantitative correlational study with a cross sectional approach. The sampling technique in this study used a purposive sampling approach. The sample used was 376 respondents with the inclusion criteria of undergraduate and diploma pharmacy students in Central Java, Indonesia. Data analysis were conducted in structural equation modeling - partial least square (SEM-PLS). The statistical results showed that attitudes had a positive effect on the willingness of pharmacy students to provide pharmaceutical services for mental illness individuals (p<0.05). However, stigma and belief do not affect the willingness of pharmacy students to provide pharmaceutical services for mental illness individuals (p>0.05). This study suggested conducting learning evaluations such as improving mental health literacy and interdisciplinary collaboration.

Knowledge and quality of life among Indonesian students during the COVID-19 pandemic Prasojo Pribadi; Lolita Lolita; Rayi Citra Ayu Pangestuti; Heni Lutfiyati; Silvia Mareti; Azis Ikhsanudin
International Journal of Public Health Science (IJPHS) Vol 10, No 2: June 2021
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v10i2.20819

The increasing of online coronavirus disease-2019 (COVID-19) information-sharing in digital media can contribute to the emergence of misinformation in public. Much insufficient knowledge will confuse public understanding and affect their quality of life. The study purposed to assess the knowledge and its influence on Indonesian students' quality of life during the COVID-19 crisis. A cross-sectional study was conducted between October and December 2020 by distributing online questionnaires. The data analysis was run through the Spearman correlation method by using SPSS version 21.0. A total of 200 respondents aged over 17 years were recruited using a snowball sampling technique. Most study respondents had insufficient knowledge about COVID-19, 23% of them had moderate knowledge, and only 17.5% had high knowledge. They obtained primary sources of COVID-19 information from social media platforms. The results showed that health science students have a better understanding than social science students (ρ<0.001). The level of knowledge has a significant associated with psychological domain (ρ=0.020), environmental domain (ρ=0.046), and overall quality of life (ρ=0.047). Thus, the media control center is vital to encounter valid information in providing better knowledge and quality of life during a pandemic.

Kesiapan Apoteker dalam Memberikan Layanan Medication Therapy Management Heni Lutfiyati; Prasojo Pribadi; Setiyo Budi Santoso
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : STIKES MUHAMMADIYAH KLATEN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Optimizing the implementation of the referral program is one of BPJS 'top programs. BPJS Health implements a referral program based on Medication Therapy Management. Medication therapy management interventions can reduce the frequency of drug-related problems, including non-compliance, and reduce health care costs. The purpose of this study was to evaluate the readiness of pharmacists in providing medication therapy management services This research uses a descriptive method by using a questionnaire as an instrument for data retrieval. The sampling technique is convenience sampling. The population is pharmacists who practice pharmaceutical services and are willing to fill out questionnaires. The result most pharmacists feel they have enough clinical knowledge and experience to provide MTM services. There are still many pharmacist workplaces (Puskesmas, Pharmacies and hospitals) that have not yet prepared to provide MTM services. Pharmacists think they have a desire to provide MTM services and have sufficient access to information in designing appropriate MTM services and pharmacists should be involved in providing MTM services. The obstacles faced by pharmacists in providing MTM services are insufficient time, insufficient human resources, limited space, limited information regarding MTM services, and the costs needed to implement MTM. Pharmacists are willing to provide Medication Therapy Management services but many obstacles remain. Training is needed so that pharmacists become more confident in providing clinical services

PEMANFAATAN PERASAN BUAH KEPEL (Stelechocarpus burahol (Blume) Hook & Thomson) SEBAGAI ANTISEPTIK LUKA Prasojo Pribadi; Elmiawati Latifah; Rohmayanti Rohmayanti
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Fruit of kepel known contain of saponin and flavonoid, fruit of kepel is a plant that hasantibacterial and antiinflamation activity. This research purposed for made juice of fruit kepeland test of open wound healing process activity. Juice of fruit kepel is made with variety ofconcentration, which 20%, 40%, 60%, and 80%. Negative control used aquadest and positivecontrol used BetadineÂ® (Povidon Iodine). This type of research is experimental research,procedure start from the preparation of test materials, first identifying plants, then make fruitjuice of kepel and divide into several concentration, followed by grouping into six group of testanimals. All quantitative data were statistically analyzed using Anaylsis of Variance (Anova)and continued with Tukey Test, The lowest activity on the negative control and increase on thegroup of juice with concentration 20%, 40%, 80%, and 60%, higher activity on the positivecontrol. With wound healing broad parameters result that the group fruit juice of kepelconcentration 60% and 80% showed the statistically analyzed was more significant (p<0.05) 178 PharmaÒ«iana, Vol. 4, No. 2, 2014: 177-183than the negative control. So it can be taken conclusion that fruit juice of kepel concentration60% and 80% having wound healing activity.

Effectiveness of banana leaves extract (Musa paradisiaca L.) for wound healing Dimas Ariandi Candra Putra; Heni Lutfiyati; Prasojo Pribadi
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Banana leaves (Musa Paradisiaca, L.) has not been widely used in the treatment purpose of this study was to examine the wound healing activity of the gel of banana leaves (Musa paradiasiaca L.) and determine the most effective concentration for wound healing.Target research is to provide natural wound treatment alternatives. The method used is eksperimental.Prosedur research study began with the identification of a banana leaf, banana leaf extraction, formulation of banana leaf extract gel with a concentration of 1%, 5%, 10% and testing to the test animals were harmed .Animal test are grouped into 5 groups the negative control group (base gel), a positive control (bioplacenton), and 3 groups treatment. Measuring ofÂ diameter wound on day-1 through day 7. The observation was tested by using ANOVA and Post Hoc Tukey HSD. ANOVA test results showed a significant difference between the mean percentage of wound healing all groups Treatment .The result ofÂ Post hoc Tukey HSD at the 95% confidence level showed significant differences in the negative control group when compared to the positive control group and the treatment group gel 5% and 10% .It indicates that the positive control, gel 5% and 10% have a wound healing effect. Positive control group compared with the group treated gel 5% and 10% showed significant differences that the average value of the percentage of wound healing is higher than the positive control treatment group. It means the difference meant that the positive control has better activity. While the group gel 5% when compared with the 10% gel group no significant difference in this case means the group gel 5% with 10% having a comparable effectiveness of wound healing.

Formulasi dan evaluasi granul effervescent ekstrak daun binahong (Anredera cordifolia (Tenore) Steen.) Indah Fortuna Rahmawati; Prasojo Pribadi; Imron Wahyu Hidayat
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The purpose of this research are to find out whether the formulation of effervescent granules from binahong leaves extract has met the standards for effervescent granules and determine the best formulation of effervescent granules. This research is descriptive experimental with data collection from evaluation of effervescent granules. To be able to make effervescent granules, extraction of binahong leaves must be made first. The extracts resulted from a maseration method with 70% ethanol. The effervescent granules formulation were made by 3 design based on their concentration F1 7.4%; F2 14.8%; and F3 22.2%. Effervescent granules of binahong leaves extract are prepared by using wet granulation method. Several physical tests were carried out on the results of effervescent granules of binahong leaves, including organoleptic test, moisture content test, pour volume test, volume of shringkage test, flow capacity test, dispersion test, and pH. The test results showed that all the effervescent granules of binahong leaves (Anredera cordifolia (Tenore) Steen.) have met the standard requirements as good granules. The third formula became the best formulation, With the best value in moisture content test, volume of shringkage test, flow capacity test, and pH.

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