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All Journal Muhammadiyah Medical Journal Jurnal MedScientiae
Wijaya, Pande I Gede Indra
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Antibiotic Susceptibility Profile in Urinary Tract Infection Patients at Tarakan Regional Hospital Dharmawan, Ade; Wijaya, Pande I Gede Indra; Septiana, Yorisye; Pasaribu, Donna Mesina Rosadini; Tan, Henny Tannady; Simanjuntak, Lasma Susi F.
Muhammadiyah Medical Journal Vol 5, No 1 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.1.28-35

Abstract

Background: Urinary tract infections (UTIs) are common in the community and hospital. In Indonesia, the incidence of UTI reaches 180,000 new cases per year. The most common pathogenic bacteria causing UTIs are dominated by Escherichia coli. Early empirical treatment of UTI cases can reduce morbidity. Knowing the pathogenic bacteria involved in urinary tract infections and their antimicrobial susceptibility patterns is necessary to provide appropriate empirical therapy. Purposes: Describe bacterial patterns and susceptibility profiles in urinary tract infection patients. Methods: A retrospective UTI dataset between 2019-2021whom admitted to Tarakan Regional General Hospital with a diagnosis of UTI. Resistance marker data for ESBL were obtained from the results of identification and resistance using the BD PhoenixTM Automated Microbiology System (Becton Dickinson, USA). The data was analyzed descriptively. Results: As many as 40 isolates were analyzed. Consist of E.coli (37.5%), Enterococcus faecium (20%) and Klebsiella pneumoniae (17.5%). The ESBL-producing E.coli bacteria rate reached 60%, while ESBL-producing K. pneumoniae reached 100%. Conclusion: E. coli was the most common pathogen, with the highest antibiotic sensitivity being imipenem, meropenem, and amikacin.
Current Management of Fluorometholone Steroids in Pediatric Vernal Conjunctivitis: A Literature Review Fajar, Muhammad Fauzi; Siallagan, Maria; Nabighah, Gladis Salsabila Najla; Wijaya, Pande I Gede Indra; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3079

Abstract

Vernal conjunctivitis is a rare allergic eye disease, usually affecting children in the prepubertal years and can last between 5 to 10 years. Treatment of this condition is often challenging, requiring effective therapies to reduce symptoms. This literature review, conducted between 2015 and 2023, aimed to evaluate the effectiveness of fluorometholone steroid use in the treatment of pediatric vernal conjunctivitis. Recent studies comparing the effectiveness of Fluorometholone 0.1% in the treatment of Vernal Keratoconjunctivitis (VKC) were analyzed. The results showed that Fluorometholone was effective compared to Cyclosporine in reducing VKC symptoms. However, the use of Fluorometholone should be done with caution due to potential side effects such as increased intraocular pressure and risk of infection.Fluorometholone is an effective treatment option for vernal conjunctivitis in children. However, it is important to have close monitoring by an ophthalmologist to avoid serious side effects. With careful monitoring and proper dose adjustment, Fluorometholone can be a safe and effective therapy in managing this condition.  
Co-Authors Ade Dharmawan Donna Mesina Rosadini Pasaribu Fajar, Muhammad Fauzi Henny Tannady Tan Nabighah, Gladis Salsabila Najla Santi Anugrahsari Septiana, Yorisye Siallagan, Maria Simanjuntak, Lasma Susi F.