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All Journal Respiratory Science Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Asian Journal of Public Health and Nursing
Dianova, Sri
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Analisis Keterlambatan Diagnosis dan Terapi Kanker Paru Di RSUD Dr. Zainoel Abidin, Banda Aceh Ferry Dwi, Kurniawan; Dianova, Sri; Rinaldy, Rinaldy
Journal of Medical Science Vol 5 No 1 (2024): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v5i1.107

Abstract

Keterlambatan diagnosis dan terapi kanker paru berdampak pada prognosis. Berbagai faktor keterlambatan yang berperan seperti keterlambatan pasien, keterlambatan pada fasilitas kesehatan tingkat pertama ataupun keterlambatan pada rumah sakit rujukan. Saat ini belum ada penelitian yang mengkaji maslah keterlambatan diagnosis dan terapi kanker paru di Indonesia. Tujuan penelitian ini adalah untuk mengetahui lama keterlambatan dan faktor yang mempengaruhi keterlambatan diagnosis dan terapi kanker paru di RSUD dr. Zainoel Abidin, Banda Aceh. Penelitian ini menggunakan studi potong lintang yang dilakukan dari bulan Juni hingga September 2022. Lama keterlambatan dihitung mulai dari keluhan pertama kali dirasa pasien hingga pasien diperiksa di Fasilitas Kesehatan Tingkat Pertama (FKTP), Poli Paru, dilakukan biopsi, diperiksa CT scan toraks, didapatkan hasil biopsi dan diberikan kemoterapi. Karakteristik umum dan lama keterlambatan dinilai dengan menggunakan program R statistik. Median hari pasien datang ke FKTP setelah keluhan pertama adalah 23 (3-368) hari dengan penyebab terbanyak adalah kendala jarak yang jauh (26.8%) dan masih bisa beraktifitas harian (21.1%) dan median hari pasien datang ke Poli Paru adalah 12 (2-140) hari dengan alasan terbanyak adalah biaya (29.6%), jarak yang jauh (28.2%). Median pasien dilakukan biopsi adalah 27.5 (3-165) hari, median dilakukan pemeriksaan CT scan toraks adalah 21 (3-242) hari, median dilakukan pembacaan hasil PA adalah 36 (4-235) hari serta median diberikan kemoterapi adalah 6 (2-134) hari. Median keterlambatan diagnosis dan terapi dihitung sejak keluhan pertama hingga mendapat kemoterapi adalah 98 (23-467) hari. Keterlambatan diagnosis dan terapi kanker paru disebabkan keterlambatan di sisi pasien dan sistem kesehatan. Faktor-faktor seperti jarak jauh, biaya, kendala diagnosis di daerah, dan menunggu persetujuan keluarga untuk pemeriksaan dan kemoterapi berperan sebagai penyebab keterlambatan diagnosis dan terapi. Kata Kunci: kanker paru, keterlambatan pasien, keterlambatan sistem kesehatan
The Relationship between Particulate Matter and Length of Exposure to Respiratory Complaints and Lung Function Disorder among Brick Craftsmen in Aceh Besar Dianova, Sri; Febriansyah, TM.; Yanti, Budi; Andayani, Novita; Yusuf, Nurrahmah; Kurniawan, Ferry Dwi; Salawati, Liza
Respiratory Science Vol. 5 No. 1 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i1.161

Abstract

Background: Brick craftsmen are heavily exposed to particulate matter (PM) from brick burning, possibly contributing to respiratory complaints. The research aims to evaluate the association between PM levels, duration of exposure, respiratory complaints, and lung function disorders among brick craftsmen in Aceh Besar. Method: The research method is observational analytic with a cross-sectional design. It was conducted in September 2023 on 68 respondents to assess lung function using spirometry and PM levels using the Air Quality Monitor. Results: The data analysis revealed restrictive types of lung function disorders (47.1%), 75% of participants had worked for more than three years with working hours ≥8 hours/day (100%), the most frequent respiratory complaint was coughing (23.5%) and shortness of breath (13.2%), and the dominant type of work was brick molding (67.6%) rather than burning (32.4%). The PM2.5 index in the brick manufacturing area is classified as very dangerous (100%), while the PM10 index is identified as very unsafe (55.6%) and very dangerous (44.4%). The correlation analysis revealed a significant connection between PM2.5 as well as PM10 and lung function impairments (values of P=0.002 and 0.012, respectively). There was a significant correlation between work periods and lung function impairments (P=0.037). Multivariate analysis showed that a working term of 1-3 years was strongly linked with lung function disorder (FEV1) among brick craftsmen in Aceh Besar (P=0.026). Conclusion: This study showed that PM exposure was significantly associated with impaired lung function but not with respiratory complaints. Furthermore, a long working period is significantly associated with respiratory symptoms, especially for workers with 1-3 years, and is associated with impaired lung function in brick artisans in Aceh Besar.
The Association of Serum Vitamin D Levels with Lung Function, Symptom Severity, and Exacerbations in Stable COPD Patients Yusuf, Nurrahmah; Mekasari, Chelsy; Dianova, Sri; Priyanto, Herry; Yanti, Budi
Asian Journal of Public Health and Nursing Vol. 1 No. 2 (2024)
Publisher : Queeva Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62377/drshg005

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a significant health burden associated with a decrease in quality of life. Patients with the disease often have a deficiency of Vitamin D, a fat-soluble vitamin important for respiratory health. A previous study suggested an association between low vitamin D levels and poor lung function, as well as increased exacerbation, and more severe COPD symptom. Therefore, this study aimed to assess serum vitamin D levels in stable COPD patients and explore association with lung function, symptom severity, and frequency of exacerbation. Methods: This was a cross-sectional study conducted from May to July 2023 at Lung Polyclinic of Dr. Zainoel Abidin Regional General Hospital (RSUDZA) Banda Aceh. A total of 30 subjects selected based on specific inclusion and exclusion criteria were included. Results: The results showed that the mean serum vitamin D level was 26.25 ng/mL, with 56.7% of subjects showing vitamin D insufficiency. Statistical analysis showed p-values of 0.58, 0.637, 0.12, and 0.98 for lung function, exacerbation, COPD Assessment Test (CAT), and Modified Medical Research Council (mMRC) dyspnoea scale respectively, indicating no significant association between vitamin D levels and these outcomes. Potential confounding factors include unassessed variables such as medication use, educational background, and psychological status. Conclusion: This study found no significant association between serum vitamin D levels and lung function, symptom severity, or frequency of exacerbation in stable COPD patients. Further studies with a larger sample size and extended follow-up are needed to confirm these results and explore additional influencing factors.
Air Quality and Correlation of Exhaled Carbon Monoxide Level with Lung Function among Petrol Station Attendants in Banda Aceh Hardisa, Rika; Kurniawan, Ferry Dwi; Dianova, Sri; Yanti, Budi; Yusuf, Nurrahmah
Respiratory Science Vol. 5 No. 3 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i3.177

Abstract

Background: Risks of developing respiratory diseases due to pollutant exposures at petrol stations are high. The pollutants, such as particulate matter, carbon monoxide (CO), and volatile organic compounds emitted from vehicle exhaust and gasoline vapours, may affect the lung function of petrol station attendants. This study aimed to assess the levels of particulate matter, total volatile organic compounds, and the correlation of CO level and lung function among petrol station attendants in Banda Aceh. Method: An analytical observational study with a cross-sectional design involved 114 attendants from 12 petrol stations in Banda Aceh. Lung function was evaluated using spirometry, and CO exhalation levels were measured using a Smokerlyzer. In addition, particulate matter and total volatile organic compounds levels were measured in the petrol station area using an air quality monitor. Results: Most participants were male (82.5%) with a mean age of 30 years. The duration of work was under 5 years in 68 participants (59.6%). Approximately 61.4% (70 samples) were active smokers, with the most common Brinkman index indicating mild smoking habits for 50 samples (43.9%). The Pearson chi-square test revealed no significant relationship between CO exhalation levels and decreased lung function (P=0.118). The level of TVOC exceeded safe limits at all gas stations (>0.601 mg/m3), with an average TVOC level of 7.53 mg/m3. Most participants showed above-normal expiratory CO levels (53.6%). The average of the PM2.5 level was moderate. Conclusion: This study found no significant correlation between exhaled CO levels and decreased lung function among petrol station attendants, likely due to their shorter duration of work and age under 40 years.
Co-Authors Febriansyah, TM. Ferry Dwi, Kurniawan Hardisa, Rika Kurniawan, Ferry Dwi Liza Salawati, Liza Mekasari, Chelsy Novita Andayani, Novita Priyanto, Herry Rinaldy Rinaldy Yanti, Budi Yusuf, Nurrahmah