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KEARIFAN LOKAL DALAM PEMANFAATAN TUMBUHAN UNTUK MENGATASI PENYAKIT DIABETES MELLITUS OLEH PENGOBAT TRADISIONAL DI KECAMATAN AMBALAU KABUPATEN BURU SELATAN Pangemanan, Victory O; Ukratalo, Abdul M; Loilatu, Muhammad Fitrah; Ichsan, Muh. Nurhidayat; Pattimura, Nadira; Manery, Dodikrisno E
Pasapua Health Journal Vol. 5 No. 2 (2023): Pasapua Health Journal
Publisher : STIKES Pasapua Ambon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62412/phj.v5i2.97

Abstract

Introduction: Diabetes is a condition in which metabolism is disrupted. The large number of people who live in rural areas, especially in areas that are difficult to reach (isolated), makes it difficult to implement even distribution of development results such as education and health. Method: This research is a form of descriptive qualitative research with an exploratory observational design. Results: There are 6 types of plants used as diabetes mellitus medicine, namely sugar apple, horse grass, suruhan, lantana, antawali and castor oil. The plant parts used as medicine for diabetes mellitus are leaves, herbs and stems. Conclusion: Annona squamosa, Panicum maximum, Peperomia pellucida, Lantana camara, Tinospora crispa and Jatropha curcas L plants have potential as diabetes mellitus drugs.
The Correlation Between The Sitting Posture and Duration With LBP Complaints in Nursing Students During Lecture Activitie Pattimura, Nadira; Makatita, Sakina; Pattimura, Nastain Abubakar; Tihurua, Ma’syari Arfah
Medicor : Journal of Health Informatics and Health Policy Vol. 2 No. 1 (2024): January 2024
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/medicor.v2i1.221

Abstract

Lower Back Pain (LBP) is a frequently reported issue among people in different domains, including students enrolled in nursing education programmes. Nursing students frequently endure prolonged periods of sitting during their participation in lecture activities. An unergonomic sitting posture and extended periods of sitting can increase the likelihood of experiencing lower back pain (LBP) complaints. This study investigated the correlation between sitting posture and duration and the occurrence of low back pain (LBP) complaints in nursing students at the College of Health Sciences of Pasapua Ambon. This research methodology was characterised by its analytical nature and relies on primary data collected using a cross-sectional approach. A total of 76 participants were included in the study, and they were provided with a Google form including a questionnaire to complete. The acquired data was subsequently examined using both univariate and bivariate methods. The findings indicated no statistically significant correlation between the sitting posture and complaints of lower back pain (LBP). A notable correlation existed between the amount of time spent sitting and lower back pain (LBP) symptoms. These findings suggest that focusing on the amount of time spent sitting rather than the specific sitting posture to reduce lower back pain complaints among university students is more crucial. This highlights the necessity of restricting extended periods of sitting while also emphasising the importance of taking sufficient breaks and engaging in frequent stretching.
Edukasi Pencegahan Penularan Penyakit Zoonosis Sebagai Upaya Meningkatkan Kesadaran Kesehatan Siswa SD Inpres Negeri Latu Basyarewan, Eko Saputra N; Ukratalo, Abdul M; La Eddy; Leimena, Handy Erwin Pier; Pattimura, Nadira; Wakanno, Ferros Rozik
TOLIS MENGABDI : Jurnal Pengabdian Kepada Masyarakat Vol 3 No 1 (2025): Juni
Publisher : Universitas Madako Tolitoli

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56630/tm.v3i1.824

Abstract

Penyakit zoonosis merupakan penyakit yang dapat menular antara hewan dan manusia, dan menjadi salah satu masalah kesehatan global. Di Indonesia, terutama di daerah pedesaan, pengetahuan masyarakat mengenai pencegahan penyakit zoonosis masih terbatas. Kegiatan pengabdian Masyarakat ini dilakukan dengan tujuan untuk memberikan edukasi mengenai pencegahan penularan penyakit zoonosis kepada siswa SD Inpres Negeri Latu guna meningkatkan kesadaran kesehatan mereka. Kegiatan ini dilaksanakan pada tanggal 10 Agustus 2024. Siswa yang hadir dalam kegiatan ini adalah siswa kelas 4,5 dan 6 berjumlah 57 orang. Metode yang digunakan dalam kegiatan ini adalah pendekatan edukasi melalui penyuluhan. Hasil dari kegiatan ini menunjukkan siswa SD Inpres Negeri Latu semakin sadar akan pentingnya menjaga kesehatan dan kebersihan diri untuk mencegah penularan penyakit zoonosis. Mereka menjadi tahu cara pencegahan penyakit zoonosis, seperti menjaga kebersihan lingkungan, mencuci tangan setelah berinteraksi dengan hewan, serta menghindari kontak langsung dengan hewan yang berpotensi membawa penyakit. Edukasi ini diharapkan dapat menjadi upaya preventif yang efektif dalam mengurangi risiko penularan penyakit zoonosis di kalangan anak-anak dan masyarakat sekitar.
POTENSI KULIT BATANG Cinnamomum burmannii Bl. DALAM MENCEGAH INFERTILITAS; KAJIAN TERHADAP BERAT TESTIS DAN JUMLAH SPERMATOZOA MENCIT (Mus musculus) MODEL DIABETES MELLITUS TIPE-1 Moniharapon, Mechiavel; Ukratalo, Abdul M; Pattimura, Nadira; Samson, Efraim; Pangemanan, Victory O
Biofaal Journal Vol 4 No 2 (2023): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v4i2pp108-117

Abstract

In individuals with diabetes mellitus, the increase in Reactive Oxygen Species (ROS) can damage the mitochondrial membrane, leading to the loss of potential mitochondrial membrane function in inducing apoptosis of sperm cells. Cinnamomum burmannii is a type of spice that contains antioxidants, thus capable of neutralizing free radicals and reducing oxidative stress caused by diabetes mellitus. Flavonoids also have an effect on increasing spermatogenesis. The aim of this research is to examine the role of methanol extract from Cinnamomum burmannii bark in increasing testis weight and spermatozoa count in type-1 diabetes mellitus mice (Mus musculus). The study employs a Completely Randomized Design (CRD) with five treatments and three replications. Twenty mice are divided into groups: K- (control), K+ mice injected with STZ without medication), P1 (dose of 200 mg/kg BW), P2 (dose of 400 mg/kg BW), and P3 (dose of 800 mg/kg BW). Before administering the Cinnamomum burmannii bark extract, blood sugar levels are measured in the K+, P1, P2, and P3 groups. If blood sugar levels have increased (>128 mg/dL), the P1, P2, and P3 groups are given the Cinnamomum burmannii bark extract according to the predetermined dosage. The treatment is carried out for 14 days. On the last day, surgery is performed to extract the testes and observe the spermatozoa count. The observation data on testis weight and spermatozoa count will be analyzed using ANOVA with SPSS 24.0. The results indicate that the administration of methanol extract from Cinnamomum burmannii bark significantly affects the increase in testis weight and spermatozoa count in type-1 diabetes mellitus mice. The increase in testis weight and spermatozoa count is proportional to the dosage given
ANALISIS KADAR ENZIM SGPT MENCIT TERINFEKSI Plasmodium berghei UNTUK MENETAPKAN AKTIVITAS GAMBIR LAUT (Clerodendrum inerme ) SEBAGAI HEPATOPROTEKTIF Pattimura, Nadira; PATTIMURA, NASTAIN ABUBAKAR
Pasapua Health Journal Vol. 5 No. 1 (2023): Pasapua Health Journal
Publisher : STIKES Pasapua Ambon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62412/phj.v5i1.94

Abstract

Introduction : Malaria, caused by the Plasmodium parasite transmitted by Anopheles mosquitoes, remains a serious health problem in Indonesia and throughout the world. Research on the effect of Gambir Laut leaf extract on malaria and its impact on liver damage is very important in overcoming the spike in malaria cases in Indonesia.Method: This research is a laboratory experiment.Results: The results of measuring SGPT enzyme levels showed that the administration of Gambir Laut infusion extract could reduce SGPT enzyme levels in mice infected with Plasmodium berghei ANKA. The lowest SGPT levels were in the group of infected mice that were only given a 10% dose of Sea Gambir extract.Conclusion: Based on the results of this study it can be concluded that administration of Gambir Laut infusion extract at doses of 01.%, 1% and 10% in mice infected with Plasmodium berghei ANKA can reduce levels of the SGPT enzyme.
Phytochemical and Bioactivity Study of Sargassum duplicatum as a Candidate Natural Biolarvicide Compound Pattimura, Nadira; Pattimura, Nastain Abubakar
Biofaal Journal Vol 6 No 2 (2025): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v6i2pp90-104

Abstract

Dengue hemorrhagic fever (DHF) is an endemic disease found in nearly all provinces of Indonesia. The occurrence of DHF is closely associated with climatic factors on spatial, temporal, and spatio-temporal scales. The search for new methods to eliminate the sources of dengue virus transmission is both urgent and essential. Sargassum duplicatum, a species of brown seaweed native to Indonesia, has been shown to possess potential antioxidant properties. This alga contains bioactive compounds, including steroids, alkaloids, phenols, flavonoids, saponins, and tannins, which are suspected to be toxic to insects. This study aimed to evaluate the larvicidal activity and determine the LC₅₀ and LC₉₀ values of ethanol extract from Sargassum duplicatum against the larvae of Aedes aegypti mosquitoes. A completely randomized design (CRD) was employed, consisting of five treatment groups with three replications each. A total of 300 third-instar Aedes aegypti larvae were introduced into treatment containers containing predetermined concentrations of Sargassum duplicatum ethanol extract, with each container holding 20 larvae. Observational data were analyzed using ANOVA and probit analysis. Phytochemical screening of the ethanol extract from Sargassum duplicatum confirmed the presence of flavonoids, saponins, tannins, and alkaloids. The extract demonstrated increased larval mortality in Aedes aegypti with increasing concentrations. A concentration of 75 ppm exhibited larvicidal efficacy comparable to that of 1% Abate. The LC₅₀ value of the ethanol extract was calculated to be 9.098 ppm, while the LC₉₀ value was 20.485 ppm.