Garuda - Garba Rujukan Digital

Peran Motivasi Internal dalam Pengobatan Penyakit Fibromyalgia M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Ika Sandra Dewi; Milna Sari
Jurnal Anestesi Vol. 2 No. 4 (2024): Oktober : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i4.1408

This research examines the role of internal motivation in the success of fibromyalgia treatment through a systematic review and meta-analysis. Out of 1,247 identified articles, 27 studies met the inclusion criteria. The meta-analysis results indicate a significant positive correlation between internal motivation and medication adherence (r = 0.42, p < 0.001), as well as quality of life (r = 0.38, p < 0.001) among fibromyalgia patients. Additionally, a significant negative relationship was found between internal motivation and pain intensity (r = -0.31, p < 0.001). Moderator analysis revealed that the effect of internal motivation is stronger in behavioral interventions compared to pharmacological treatments (Q = 8.7, p = 0.003). Furthermore, meta-regression results indicated that disease duration significantly moderates the relationship between internal motivation and fibromyalgia treatment (? = -0.02, p = 0.03), with internal motivation having a more substantial effect in patients with a longer duration of illness. Additionally, the average age of fibromyalgia patients was found to moderate the relationship between internal motivation and patient quality of life (? = 0.01, p = 0.02). Among six clinical trials evaluating interventions to enhance internal motivation, the meta-analysis showed a significant effectiveness (d = 0.56, 95% CI: 0.38 to 0.74, p < 0.001). Consequently, these findings extend previous research by Ng et al. (2015) on the role of internal motivation in chronic conditions, demonstrating its strong relevance in the context of fibromyalgia. This study also differs from Karlsson et al. (2019), which did not find a significant correlation. The results reveal a consistent relationship between internal motivation and fibromyalgia treatment outcomes. Lastly, the novelty of this study lies in identifying specific moderating factors and providing a comprehensive evaluation of motivation-based interventions in the context of fibromyalgia.

Pengaruh Dukungan Keluarga Terhadap Efektivitas Terapi Penyakit Crohn Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Milna Sari
Jurnal Anestesi Vol. 2 No. 4 (2024): Oktober : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i4.1425

This study examines the impact of family support on the effectiveness of Crohn's disease therapy through a meta-analysis of 18 studies involving 5,876 patients. The analysis reveals a significant positive effect (Hedges' g = 0.58, 95% CI [0.42, 0.74], p < .001) of family support on various therapeutic outcomes. The strongest effect was observed in the dimensions of quality of life (g = 0.67, 95% CI [0.48, 0.86]) and clinical remission (OR = 2.14, 95% CI [1.68, 2.73]). Furthermore, emotional support was found to have the largest effect (g = 0.63, 95% CI [0.45, 0.81]) compared to other types of family support. Mediation analysis indicated that medication adherence (indirect effect = 0.15, 95% CI [0.08, 0.22]), stress reduction (0.12, 95% CI [0.05, 0.19]), and increased self-efficacy (0.09, 95% CI [0.03, 0.15]) were significant mediators in the relationship between family support and Crohn's disease treatment efficacy. Additionally, a stronger effect of family support was observed in patients with more severe disease (Q = 4.82, p = .028) and samples with a higher proportion of females (? = 0.012, p = .03). These findings extend the work of Sewitch et al. (2001) and Moradkhani et al. (2013) by providing a more precise quantification of the effects of family support and identifying several key moderators. Unlike Trindade et al. (2017), this study consistently found a positive effect of family support on Crohn's disease therapy. The novelty of this research lies in identifying specific mechanisms and moderating factors affecting the relationship between family support and therapy effectiveness, offering a deeper understanding of the complex role of family support in Crohn's disease management.

Pengaruh Kecemasan Terhadap Kepatuhan Pengobatan Kanker Payudara M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Milna Sari
Jurnal Medika Nusantara Vol. 3 No. 3 (2025): Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i3.1354

Anxiety is a psychological factor commonly experienced by breast cancer patients and can influence medication adherence. This study aims to analyze the impact of anxiety on medication adherence among breast cancer patients through a meta-analysis of published studies. A systematic search was conducted across electronic databases, including PubMed, Scopus, and PsycINFO, to identify relevant studies published in the last five years. Inclusion criteria encompassed observational and experimental studies measuring anxiety levels and medication adherence in breast cancer patients. A meta-analysis was performed using a random-effects model to compute the effect size. The analysis revealed a significant negative relationship between anxiety levels and adherence to breast cancer treatment (r = -0.38, 95% CI: -0.45 to -0.31, p < 0.001). These findings indicate that patients with higher levels of anxiety are likely to have lower adherence to breast cancer treatment. Consequently, the findings underscore the importance of psychological interventions in reducing patient anxiety and improving medication adherence in breast cancer patients. Finally, the study highlights the need for clinical implications and future research recommendations. The results reinforce the necessity for further research and development in improving treatment outcomes and quality of life for breast cancer patients in the future.

Hubungan antara Perasaan Bersalah dan Keberhasilan Pengobatan Lupus Romaito Nasution; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Ika Sandra Dewi; Milna Sari
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1858

This study analyzes the relationship between guilt and treatment outcomes in lupus patients through a meta-analysis of 15 studies (N = 2,876). The results indicate a significant negative correlation (r = -0.32, 95% CI [-0.39, -0.25], p < 0.001) between levels of guilt and lupus treatment success. Moderator analysis revealed a stronger relationship in younger patients (β = 0.015, SE = 0.006, p = 0.013) and those with a shorter disease duration (β = -0.021, SE = 0.009, p = 0.019). The strongest correlation was found in the disease activity dimension (r = -0.38, 95% CI [-0.46, -0.29]) compared to quality of life (r = -0.30, 95% CI [-0.38, -0.21]) or medication adherence (r = -0.25, 95% CI [-0.34, -0.15]). Furthermore, mediation analysis revealed that coping strategies mediated 34% of the effect of guilt on treatment outcomes. Longitudinal findings confirmed that a decrease in guilt is associated with improved treatment outcomes (r = -0.29, 95% CI [-0.41, -0.16], p < 0.001). These findings extend Witvliet et al. (2001) regarding the impact of guilt on health and support Engel's biopsychosocial model (1977) in the context of lupus. Unlike Navarrete-Navarrete et al. (2010), which focused on a single case, this research provides large-scale quantitative evidence. Finally, the primary novelty of this study lies in identifying the non-linear relationship between guilt levels and treatment outcomes, as well as the moderating role in psychological interventions (Q = 4.12, df = 1, p = 0.042). Thus, the findings underscore the importance of integrating guilt assessment and management in lupus care, supporting a holistic approach that combines psychological interventions with medical treatment.

Efek Kecemasan Sosial pada Pengobatan Penyakit Behçet Luthfiah Mawar; M. Agung Rahmadi; Helsa Nasution; Milna Sari
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 1 No. 4 (2024): Oktober : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v1i4.807

Behçet's disease is a multisystem inflammatory disorder that can significantly impact patients' quality of life. This study conducts a meta-analysis aimed at elucidating the effects of social anxiety on treatment outcomes for Behçet's disease through a comprehensive synthesis of existing literature. Initially, a systematic search was performed across major electronic databases to identify relevant studies published between 2014 and 2024. Out of 1,253 initially identified articles, 18 studies met the inclusion criteria, encompassing 2,487 Behçet's disease patients. The meta-analysis revealed a significant negative correlation between social anxiety levels and treatment adherence for Behçet's disease (r = -0.42, p < 0.001), which was positively associated with disease symptom severity (g = 0.58, 95% CI [0.41, 0.75]). Moderator analysis indicated that the effect of social anxiety on Behçet's treatment outcomes was more pronounced in patients with mucocutaneous manifestations (Q = 7.23, p = 0.007). Additionally, social anxiety showed a strong negative correlation with patients' quality of life in health (r = -0.53, p < 0.001), with the most substantial impact observed in the social functioning domain. Furthermore, thematic analysis of the potential mechanisms underlying the relationship between anxiety and Behçet's treatment outcomes confirmed the mediating roles of patient-doctor communication barriers, increased stigma perception, and avoidance behaviour. These findings underscore the importance of assessing and addressing social anxiety in the comprehensive management of Behçet's disease. The researchers suggest that these findings could have implications for improving patient treatment and quality of life. Finally, the study supports the integration of targeted psychological interventions into standard care protocols for Behçet's disease and emphasizes the need for a biopsychosocial approach to managing this condition.

Efek Emosi Negatif pada Pengobatan Penyakit Endometriosis Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Ika Sandra Dewi; Milna Sari
Observasi : Jurnal Publikasi Ilmu Psikologi Vol. 2 No. 4 (2024): November : Observasi: Jurnal Publikasi Ilmu Psikologi
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/observasi.v2i4.781

This meta-analysis investigates the impact of negative emotions on the effectiveness of endometriosis treatment. Of the 1,245 articles identified, 32 studies (n=4,876 patients) met the inclusion criteria. The results revealed a significant negative correlation between negative emotions and treatment effectiveness (r = -0.38, 95% CI [-0.45, -0.31], p < 0.001). Subgroup analysis further demonstrated a stronger effect on medical treatments (r = -0.43) compared to surgical treatments (r = -0.29, p = 0.02). Additionally, negative emotions were most strongly correlated with pain intensity (r = -0.45), followed by quality of life (r = -0.39), medication adherence (r = -0.33), and patient satisfaction with treatment (r = -0.28, p = 0.02). The meta-analysis of randomized controlled trials (RCTs) (n=8) indicated that psychological interventions could significantly enhance endometriosis treatment outcomes (SMD = 0.58, 95% CI [0.39, 0.77], p < 0.001), with cognitive-behavioural therapy (CBT) being the most effective intervention (SMD = 0.67). Furthermore, the study found that the average age of patients moderates the relationship between negative emotions and endometriosis treatment (β = -0.015, p = 0.03), specifically indicating that the strongest effects of negative emotions are observed in younger patients. Finally, mediation analysis identified that pain perception, medication adherence, and maladaptive coping mechanisms are key mechanisms in the relationship between negative emotions and treatment effectiveness. These findings extend previous research by As-Sanie et al. (2014) and Lagana et al. (2017) by quantifying the impact of negative emotions and validating the effectiveness of psychological interventions as a novel contribution. The researchers advocate for a biopsychosocial approach in endometriosis management to facilitate routine screening for psychological issues and recommend the integration of holistic interventions combining medical and psychological support into standard endometriosis care.

The Analysis Of Sharia Conformity To Kafalah Contract and Hasanah Card Products In Islamic Banking Faulina Faulina; Galih Mareta Nur Ka’bah; Milna Sari; Zaitun Qamariah
Ekonomi Keuangan Syariah dan Akuntansi Pajak Vol. 1 No. 3 (2024): Juli : Jurnal Ekonomi Keuangan Syariah dan Akuntansi Pajak
Publisher : Asosiasi Riset Ekonomi dan Akuntansi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/eksap.v1i3.172

This study focused on assessing the conformity of sharia to kafalah contracts in Hasanah Card products. The main findings show that the implementation of kafalah contracts on Hasanah Cards still does not fully meet the required Sharia criteria. The majority of scholars are of the view that the agreement related to ujrah for kafalah services falls into the category of riba qardh, so it is forbidden. Therefore, it is important to keep the kafalah in its purity context as a form of aid and almsgiving without any element of imbalance or compensation that is not under the principles of Shariah. This research is expected to make a significant contribution to the development of Islamic financial products that are more in line with Islamic teachings. By highlighting shortcomings in the implementation of the kafalah contract in the Hasanah Card product, it is hoped that it will encourage better improvement and innovation efforts to ensure Sharia compliance in Islamic finance practices. In addition, this research is also expected to increase public awareness of the importance of applying sharia principles in every aspect of finance, to create a more transparent, fair, and under Islamic values.

Peran Kecerdasan Emosional dalam Pengobatan Cystic fibrosis Luthfiah Mawar; M. Agung Rahmadi; Helsa Nasution; Nurzahara Sihombing; Romaito Nasution; Milna Sari
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 4 (2024): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i4.4421

This study investigates the role of emotional intelligence (EI) in cystic fibrosis (CF) treatment through a comprehensive meta-analysis of 47 studies involving 5,823 CF patients. Results affirm a significant positive correlation between EI and treatment adherence (r = 0.62, p < 0.001), as well as improved quality of life (QoL) for CF patients (β = 0.58, 95% CI [0.49, 0.67]). Regression analysis revealed that EI predicts 37% of the variance in lung function (FEV1) (R² = 0.37, F(1, 5821) = 3421.76, p < 0.001). Furthermore, patients with high EI scores exhibited significantly reduced levels of anxiety (d = -0.79) and depression (d = -0.83) compared to control groups. These findings extend previous research by Salovey et al. (2002) and Ceyhan et al. (2024) by identifying specific EI mechanisms influencing CF treatment outcomes. Unlike Cox et al.'s (2020) study focusing on the general population, our findings specifically demonstrate the effectiveness of EI-based interventions in improving clinical outcomes for CF patients, with an average FEV1 increase of 12% after 6 months of intervention. Lastly, mediation analysis indicated that emotion regulation (β = 0.31, p < 0.001), adaptive health behaviors (β = 0.28, p < 0.001), and utilization of social support (β = 0.22, p < 0.001) mediated the relationship between EI and CF treatment outcomes. These findings underscore the importance of integrating EI training into standard CF care protocols to enhance holistic treatment outcomes.

Efek Kepuasan Hidup pada Pengobatan Sarcoidosis Milna Sari; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Nurzahara Sihombing; Romaito Nasution
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 4 (2024): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i4.4423

This meta-analysis investigated the effect of life satisfaction on Sarcoidosis treatment outcomes across 47 studies encompassing 8,932 patients. The findings revealed a significant positive correlation between life satisfaction and treatment success (r = 0.62, p < 0.001). Patients with high life satisfaction scores (>7.5/10) demonstrated a 73% higher likelihood of achieving remission compared to those with low scores (<5/10) (OR = 2.84, 95% CI: 2.31-3.49). Regression analysis indicated that each one-point increase in life satisfaction scores was associated with an 18% reduction in Sarcoidosis relapse rates (β = -0.18, p = 0.002). Treatment adherence and health behaviors were found to mediate the relationship between life satisfaction and Sarcoidosis treatment outcomes, accounting for 42% and 35% of the variance, respectively. Moderator analyses demonstrated stronger effects among patients with disease duration <5 years (p = 0.011) and those with mild to moderate disease severity (p = 0.003). These findings extend the work of Lee et al. (2020) and Martínez-García et al. (2021) by demonstrating a more pronounced effect of life satisfaction on Sarcoidosis treatment compared to other chronic conditions. Notably, contrary to Saketkoo et al (2021) previous study, the effect of life satisfaction remained significant even after controlling for patients' socioeconomic factors (β = 0.41, p < 0.001). These results underscore the crucial role of psychosocial interventions in enhancing Sarcoidosis treatment efficacy, offering new perspectives in the management of this chronic condition.

Hubungan Dukungan Sosial dalam Pengobatan Sklerosis Multipel Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Nurzahara Sihombing; Romaito Nasution; Milna Sari
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 4 (2024): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i4.4424

This meta-analysis examined the relationship between social support and medication adherence among multiple sclerosis (MS) patients through a synthesis of 47 studies (N=12,356). The findings confirmed a significant positive correlation (r=0.42, p<0.001, 95% CI [0.38, 0.46]) with substantial heterogeneity (I²=84.0%). Contrary to Cohen et al.'s (2019) finding that informational support was the strongest predictor, our moderator analyses revealed emotional support as the most robust predictor (β=0.39, p<0.001). Furthermore, this research demonstrated that the effects of social support on MS medication adherence were stronger among women (β=0.18, p=0.023) and patients with longer disease duration (β=0.24, p=0.009), extending Franqueiro et al.'s (2023) findings regarding gender differences in social support effectiveness. Family support showed the largest effect (r=0.48, p<0.001), followed by friends (r=0.40, p<0.001) and healthcare providers (r=0.35, p<0.001). Moreover, mediation modeling revealed a significant role of self-efficacy (indirect effect=0.21, 95% CI [0.17, 0.25]), expanding upon Bandura's (2018) model. Supporting Lavorgna et al.'s (2018) findings, our results confirmed that online social support proved equally effective as offline support (Q=1.87, p=0.171). These findings demonstrated robustness through sensitivity analyses and trim-and-fill procedures, confirming resilience against publication bias (adjusted r=0.39, 95% CI [0.35, 0.43]). The novelty of this research lies in its comprehensive identification of key moderators and underlying mechanisms in the social support-medication adherence relationship and the first empirical testing of an integrated mediation model incorporating social support, self-efficacy, and medication adherence in the MS context.

Title

Found 13 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 13 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 13 Documents
Search