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All Journal Althea Medical Journal Care : Jurnal Ilmiah Ilmu Kesehatan INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Bioculture Journal
I’tishom, Reny
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Agriculture, Biological Sciences & Forestry Humanities Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Penile Length of Prepubertal Children in Surabaya Susiana, Okta Margarita; Yuliawati, Tri Hartini; Purwanto, Bambang; Rezano, Andri; I’tishom, Reny
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n3.3094

Abstract

Background: Early recognition of phallic size abnormalities is essential to identify underlying endocrine and genetic disorders. Parents are concerned regarding their son’s penis length, especially obese and short-stature boys. This study aimed to investigate the factors of penile length in prepubertal boys aged 9-11 in Surabaya.Methods: A cross-sectional analytic observational study was conducted between October and November 2021 during the community services program of the Andrology Study Program, Universitas Airlangga. One hundred forty-eight healthy boys aged 9-11 years were enrolled in this study. Penile parameters and anthropometric measures were recorded. Data were analyzed with Spearman Rho’s formula to correlate the variables studied.Results: The average penile lengths and penile circumference of the penis were 6.3±1.4 and 5.2±1.0 cm, respectively. This study found two boys with micropenis (1.35%) with normal and overweight body mass index (BMI). The penile length was positively correlated with height but not with BMI.Conclusion: Androgen and growth hormones significantly influence penile length. Children with abnormal BMI tend to have smaller penile sizes, associated with increasing androgen aromatization.
RELATIONSHIP BETWEEN KNOWLEDGE AND INTEREST IN USING MENSTRUAL CUPS IN WOMEN OF REPRODUCTIVE AGE Marpaung, Zahra Thamizya; I’tishom, Reny; Jayanti, Ratna Dwi
Indonesian Midwifery and Health Sciences Journal Vol. 9 No. 2 (2025): Indonesian Midwifery and Health Sciences Journal, April 2025
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v9i2.2025.177-190

Abstract

Background: Menstrual cups have many advantages compared to other menstrual products but have not been widely used and are less desirable due to limited knowledge. In Indonesia, the majority of women use disposable sanitary napkins as menstrual products because they can be easily found even though the use of sanitary napkins can have a negative impact on health and the environment. The objective of this research is to analyze the relationship between knowledge and interest in using menstrual cup among women of reproductive age. Method: This study was an observational analytic study with a cross sectional approach. The sampling technique used sequential sampling. The sample size studied was 100 women of reproductive age in the service area of Mulyorejo Health Center, Surabaya, Indonesia who met the inclusion criteria. The research instrument used a questionnaire containing a list of questions related to knowledge and interest in using menstrual cups. Data were analyzed using the chi square test. Results: The results of this study showed that out of 100 respondents, 52 respondents (52%) had poor knowledge, 31 respondents (31%) had sufficient knowledge and 17 respondents (17%) had good knowledge. A total of 69 respondents (69%) were not interested in using menstrual cups. The results of the chi square test analysis showed a p value of 0.086 (p> 0.05). Conclusion: There is no significant relationship between knowledge and interest in using menstrual cup.
Potential of functional candies from ethanol extracts of Myristica fragrans and Phyllanthus acidus as antioxidant and anti-anxiety agents: A comprehensive review Fauzana, Anindita Azkia; Maheswari, Efada Aini Ayu; Angeline, Jennifer; Santoso, Azizah Bonitha Zahrah; I’tishom, Reny
Bioculture Journal Vol. 3 No. 1: July (2025)
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/bioculture.v3i1.2025.1798

Abstract

Background: Anxiety disorders are a major global health burden, with recent WHO data indicating a 1.79% increase in case incidence rate (CIR) and a 6.25% rise in disability-adjusted life years (DALY) over the past five years. Conventional pharmacotherapies such as SSRIs and benzodiazepines are limited by adverse effects and dependency risks, highlighting the urgent need for safer, effective alternatives. Myristica fragrans (nutmeg) and Phyllanthus acidus (otaheite gooseberry) are rich in myristicin and flavonoids, respectively, both of which exhibit promising anxiolytic and neuroprotective properties. However, the synergistic efficacy and safety of their combined use remain underexplored. Methods: A comprehensive review was conducted following PRISMA guidelines. Out of 512 studies identified from Scopus, PubMed, ScienceDirect, and EBSCO, 36 met inclusion criteria after quality appraisal using CASP, with 2 clinical trials extracted for quantitative synthesis. Data extraction focused on changes in anxiety scores (e.g., HAM-A), stress biomarkers (cortisol, MDA), antioxidant enzyme activities (SOD, CAT), and neurochemical modulation (serotonin, GABA, dopamine). Findings: analysis revealed that combined administration of nutmeg and otaheite gooseberry extracts reduced anxiety scores by a weighted mean difference (WMD) of –7.3 (95% CI: –9.1 to –5.5, p<0.001) on the HAM-A scale compared to placebo. Cortisol levels decreased by 18.4% (p=0.002), while MDA levels dropped by 22.7% (p=0.001), and SOD activity increased by 31.6% (p<0.001) in preclinical models. Myristicin (500 mg/kg) produced significant anxiolytic effects via serotonergic and GABAergic modulation, while flavonoids (1.2–3.5% content) provided robust neuroprotection against oxidative stress. No antagonistic interactions or increased toxicity were observed; the combination outperformed single extracts and showed comparable efficacy to SSRIs and benzodiazepines with fewer adverse effects. Conclusions: The integration of Myristica fragrans and Phyllanthus acidus extracts offers a synergistic, natural therapeutic approach for anxiety disorders, combining potent anxiolytic and neuroprotective effects with an excellent safety profile. Novelty/Originality of this article: This review is the first to quantitatively demonstrate the synergistic anxiolytic and antioxidant efficacy of nutmeg and otaheite gooseberry extracts, supporting their development as innovative functional candies for mental health management.
GAMBARAN DERAJAT KEPARAHAN GEJALA PASIEN RINOSINUSITIS KRONIK DI RSUD DR. SOETOMO SURABAYA Samara, Anggita Putri; Sutikno, Budi; I’tishom, Reny
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 2 (2020): EDITION JULY 2020
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.126 KB) | DOI: 10.33366/jc.v8i2.1666

Abstract

Chronic rhinosinusitis (CRS) is a sinus paranasal and nasal inflammation marked with two or more symptoms, nasal congestion or nasal discharge and the other symptom like facial pain and reduced smell may present. This symptom occur >12 weeks. One of the parameter for symptom’s severity assessmentis using Visual Analog Scale (VAS) that can be classified as mild (0-3), moderate (4-7), dan severe (8-10). This study was a observational study by assessing patient’s medical record at SMF THT-KL RSUD Dr. Soetomo and analyzed descriptively. 43 patients were enrolled to study (28 male and 15 female), most of them were between age 36-45 years old (25,58%). Most of the patient’s symptom’s severity in general, nasal obstruction, nasal discharge, facial pain, and reduced smell were moderate (65,11%), moderate (58,13%), mild (41,86%), mild (58,13%), mild (62,79%) respectively. Most of the patients had risk factor (62,79%), and the most of the patient’s risk factor were allergy. Most of the CRS patients in this study were male, 36-45 years old, with the general symptom’s severity moderate, moderate nasal obstruction, mild nasal discharge, mild facial pain, mild reduced smell, and had allergy.
Co-Authors Angeline, Jennifer Bambang Purwanto Fauzana, Anindita Azkia Jayanti, Ratna Dwi Maheswari, Efada Aini Ayu Marpaung, Zahra Thamizya Rezano, Andri Samara, Anggita Putri Santoso, Azizah Bonitha Zahrah Susiana, Okta Margarita Sutikno, Budi Yuliawati, Tri Hartini