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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Journal Of Vocational Health Studies Jurnal Keperawatan Padjadjaran Jurnal Medik Veteriner PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat J-Dinamika: Jurnal Pengabdian Kepada Masyarakat JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Jurnal Layanan Masyarakat (Journal of Public Service) COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Asian Journal of Health Research
Fatimah, Nurmawati
Department Of Anatomy, Histology, And Pharmacology, Faculty Of Medicine, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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The Profiles of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) Patients in Tertiary Hospital William Andrew Isaac; Damayanti Damayanti; Nurmawati Fatimah; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.116-122

Abstract

Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe eruptive skin reactions that can cause death. The incidence of SJS and TEN cases in the United States is 1.5–9.6 per 1,000,000 per year. Drugs are the primary etiology of SJS and TEN. Some drugs are at high risk and used frequently. The SJS and TEN mortality rates were relatively high, with SJS 4.8%, SJS / TEN overlap 19.8%, and TEN 14.8%. In Indonesia, there are lack of studies on the SJS and TEN. This study is needed to determine the epidemiological profile of SJS and TEN. Purpose: This study aimed to describe SJS and TEN patients' profiles. Methods: Drug-induced SJS and TEN cases from January 2016 to December 2019 were evaluated from the medical records patients' profile, incidence, suspected drugs, risk factors, and comorbidities of SJS and TEN were described. Result: There were 28 SJS and TEN patients, comprising of 24 SJS patients (85.7%), 3 TEN patients (10.7%), and 1 SJS overlapping TEN patients (3.5%). The most common suspected drugs were paracetamol (22.2%), carbamazepine (20.4%), cefadroxil (8.8%), and ciprofloxacin (8.8%). Women (53.5%) experienced more severe drug eruptions than men (46.4%). The largest age group was 25–44 years (35.7%). Most comorbidities were epilepsy (21%), diabetes (15.7%), hypertension (15.7%), and stroke (15.7%). Conclusion: The most common manifestation was SJS with paracetamol as the most common suspected drug, followed by carbamazepine.
Adherence of NSAID Administration in Patients with Mild and Moderate Traumatic Brain Injury in Dr. Soetomo General Hospital, Surabaya Finna Permata Putri; Agus Turchan; Nurmawati Fatimah; Muhtarum Yusuf
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 2 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I22021.94-97

Abstract

Introduction: Traumatic brain injury (TBI) has a concerning incidence rate. One of the therapies for patients with TBI is non-steroidal anti-inflammatory drugs (NSAID) administration as an analgesic with proper adherence to achieve optimal therapy results. This research aimed to evaluate physicians’ NSAID administration adherence in patients with mild and moderate TBI in Dr. Soetomo General Hospital, Surabaya.Methods: This was an observational descriptive study with a retrospective design. NSAID administration adherence was graded by evaluating the dose, route, frequency, and interval of NSAID administration. The variables were evaluated by observing the medical records of inpatients with mild and moderate TBI from 1 January to 31 December 2018.Results: NSAIDs used for TBI management were metamizole, paracetamol, mefenamic acid, and ketorolac. Metamizole was administered in 10 patients (34.5%), paracetamol in 1 patient (3.4%), metamizole and  paracetamol in 15 patients (51.7%), metamizole and mefenamic acid in 1 patient (3.4%), metamizole and paracetamol with mefenamic acid in 1 patient (3.4%), and metamizole and ketorolac in 1 patient (3.4%). Adherence of paracetamol, mefenamic acid, and ketorolac administration in patients with mild and moderate TBI were well-administered in every evaluated variable. Metamizole administration’s adherence was already well-administered in drug dosage and drug administration route, but it was not well-administered in drug administration interval and frequency.Conclusion: Physicians’ adherence to NSAID administration in patients with mild and moderate TBI in Dr. Soetomo General Hospital, Surabaya was well-administered, except for metamizole.
Activities of Curcuma heyneana Rhizome and Graptophyllum pictum Leaves Combination against Staphylococcus aureus Achmad Januar Er Putra; Sutji Kuswarini; Nurmawati Fatimah; Wening Hapsari
Asian Journal of Health Research Vol. 2 No. 1 (2023): Volume 2 No 1 (April) 2023
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v2i1.33

Abstract

Introduction: Infectious diseases have always been a problem, especially in the third-world countries. Due to the uncontrolled prescription of antibiotics, several bacteria developed resistance to some antimicrobial agents. One of them is Staphylococcus aureus. There is local wisdom in Indonesia to use natural products as potent antimicrobial agents. Curcuma heyneana and Graptophyllum pictum had been used by the locals in past centuries and seemed to be an effective agent for combatting infectious diseases. Therefore, we want to evaluate the activity of the combined extract of Curcuma heyneana and Graptophyllum pictum against Staphylococcus aureus.. Material and Methods: An in-vitro test by using the test tube dilution. The test tubes consisted of seven tubes; 2 control tubes and 5 experimental tubes. We used 1000mg/ml of each extract component at the highest (i.e., 1000mg/ml for Curcuma heyneana and Graptophyllum pictum, respectively). Five-times replication was conducted for each treatment. MIC (Minimum Inhibitory Concentration) and MBC (Minimum Bactericidal Concentration) were investigated after being streaked at the agar plate and incubated at 370C for 24 hours. Results: We could not determine the MIC because the colour of the combination of the extract was cloudy. The bacteria grew at all concentrations from five-times replication, except for the negative control, therefore MBC could not be obtained. Conclusion: Staphylococcus aureus was not inhibited effectively by combined extract of Curcuma heyneana and Graptophyllum pictum.
CARING FOR PUERPERIAL MOTHERS THROUGH THE UTILIZATION OF TRADITIONAL HERBS TO OPTIMIZE THEIR HEALTH Nurina Hasanatuludhhiyah; Danti Nur Indiastuti; Yuani Setiawati; Nurmawati Fatimah
Jurnal Layanan Masyarakat Vol. 7 No. 2 (2023): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v7i2.2023.161-172

Abstract

Puerperium is a critical period in which mothers often experience physical and psychological problems, however it is the beginning of the breastfeeding process and determines the success of exclusive breastfeeding. The use of traditional herbs for postpartum mothers is part of Indonesian culture that is starting to be abandoned in urban area. This community service activity aims to increase the knowledge, attitudes and behaviour of the community regarding the importance of postpartum maternal health care and the use of traditional herbs with proper processing methods as a promotive and preventive treatment. This activity was carried out in Gubeng Surabaya District with three stages including preparation, implementation of activities and evaluation. In the preparation stage, a situation analysis was performed. Activities were conducted by delivering lectures, discussions, video demonstrations and training. The evaluation was carried out by obtaining feedback from the social and community empowerment section as well as the pre-test and post-test questionnaires filled out by the participants. Based on the evaluation, the community service can increase participants' knowledge about postpartum health care and lactation management, thereby increasing awareness to play an active role by disseminating information to the community about the importance of family and the neighbourhood support for postpartum and breastfeeding mothers. The participants 'knowledge about the use of traditional medicinal plants for the maintenance of postpartum health and successful breastfeeding also increased, accompanied by an increase in the participants' willingness to prepare traditional jamu from fresh herbal ingredients themselves. This community service needs to be carried out in a sustainable manner with innovative delivery methods.
Treatment of Acute Diarrhea in Children Aged 1–5 Years Provided by Doctors in Surabaya Alpha Fardah Athiyyah; Insyira Rayhana Irsan; Nurmawati Fatimah
Folia Medica Indonesiana Vol. 59 No. 2 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v59i2.44723

Abstract

Highlights: 1. The focus of this study was on the treatment methods for acute diarrhea, which have not been extensively investigated in the region studied.2. This study can provide an overview of doctors' adherence to the available guidelines for the treatment of acute diarrhea in children aged 1–5 years in Surabaya, Indonesia. Abstract: Diarrhea is the second leading cause of death among children under five, following pneumonia. Insufficient knowledge of diarrhea and dehydration management may contribute to this high mortality rate. Implementing prompt and effective management and prevention strategies has the potential to decrease morbidity and mortality associated with diarrhea. Therefore, this cross-sectional study aimed to investigate the treatment methods used by doctors for children aged 1–5 suffering from acute diarrhea in Surabaya, Indonesia. Data were collected from doctors in Surabaya using an online form containing case-based questions. Microsoft Excel for Mac version 16.17 (Microsoft Inc., Redmont, WA, USA) was used to process the binary data by calculating frequencies and percentages with a point estimate of 95% confidence interval (CI). A descriptive method was used in the data analysis, and the findings were presented in tables. From a total of 51 respondents who participated in this study, 18 (35.29%) only administered oral rehydration therapy. In addition, 49 respondents (96.08%) prescribed zinc supplementation for ten days, while 10 respondents (19.61%) opted for antibiotics. Interestingly, 49 respondents (96.08%) recommended both breast milk and food for the patients, and nearly all respondents provided guidance to the mother or caregiver of the patient. The findings of this study suggested that the respondents primarily used rehydration therapy to treat children suffering from acute diarrhea with moderate dehydration. However, some respondents still relied on antibiotics despite the available recommendations to use oral rehydration therapy. Nearly all respondents agreed on zinc supplementation, breast milk and food provision, and advice for the mother or caregiver of the patient. While certain aspects of the disease management for diarrhea align with the recommended guidelines, there is room for improvement in promoting the exclusive use of oral rehydration therapy and reducing unnecessary antibiotic prescriptions. 
The Effect of Topical Gel Ethanol Extract of Gotu Kola Leaf (Centella Asiatica (L.) Urban) on Wound Healing in a White Male Rat (Rattus Norvegicus) Induced by Streptozotocin I Dewa Ayu Sudiari Dewi; Nurmawati Fatimah; Sutji Kuswarini
Surabaya Physical Medicine and Rehabilitation Journal Vol. 5 No. 2 (2023): SPMRJ, AUGUST 2023
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v5i2.47921

Abstract

Background: Diabetes mellitus (DM) can have a number of consequences, one of which is diabetic neuropathy, which can cause sores, notably in patients' feet. Wound therapy with synthetic drugs in diabetes is still not functioning as well as expected. Centella Asiatica (L.) Urban has been demonstrated to promote wound healing through a variety of mechanisms, including collagen synthesis stimulation, fibroblast proliferation stimulation, antiulcer, antibacterial, and antioxidant activity. Pharmaceutical treatments for wound healing are routinely utilized upon the assumption that a moist wound is a gel. Aims: The purpose of this study was to see how a topical gel ethanol extract of gotu kola (Centella Asiatica (L.) Urban) promoted wound healing in streptozotocin (STZ)-induced white male rats (Rattus Norvegicus). Methods: This is an experimental study using twenty white male rats (Rattus Norvegicus) caused by STZ. The rats were placed into four groups, each with five rats. These four groups are the control group, the treatment group P1 (ethanol gel gotu kola leaf at 2.5% concentration), the treatment group P2 (ethanol gel gotu kola leaf at 5% concentration), and the treatment group P3 (ethanol gel gotu kola leaf at 10% concentration). STZ was used to promote blood sugar elevation in the rats. The wound healing rate was estimated by comparing the wound healing rates of each group using macroscopic observation. Result: The findings of this study revealed that extract gel gotu kola leaf concentration applied to the wound on days 4, 7, 11, and 14 has a statistically significant influence on wound healing (p=0.000). Conclusion: Based on the research conducted, it can be concluded that gotu kola extract gel has a significant influence on the rats' wound healing.
Mental health and decision-making participation of adolescent orphans: A pilot study Annette d'Arqom; Farhan Nurdiansyah; Danti Nur Indiastuti; Mhd Zamal Nasution; Nurmawati Fatimah; Sri Purwaningsih; Yuani Setiawati; Kusuma Eko Purwantari
Jurnal Keperawatan Padjadjaran Vol. 11 No. 3 (2023): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v11i3.2358

Abstract

Background: Mental health has been brought to attention lately, with the increase of mental health problems during adolescence. In Indonesia, it is reported that one-third of adolescents develop mental health disorders. Childhood grief, separation from the family, child labor, or abuse affect the orphans’ mental health, including their decision-making participation. Purpose: As a pilot study, this study would like to investigate the mental health conditions and decision-making participation among orphans in one orphanage in Mojokerto district, East Java, Indonesia.Methods: This cross-sectional study utilizes the Depression Anxiety Scale Youth version (DASS-Y) and Child and Adolescent Participation in Decision Making Questionnaire (CAP-DMQ). Thirty-five adolescent orphans of one orphanage in Mojokerto were recruited using convenience sampling. The frequency of respondents’ mental health and decision-making participation were measured, and the mean differences between each group of sociodemographic factors were measured using the Mann-Whitney U test or the Kruskal Wallis test. Association between mental health and decision-making participation was calculated using Chi-square test.Results: The results show that 40% of respondents were categorized as having mild mental health problems, including depression, anxiety, and stress. Mental health problems are mostly found in males (22.90%) and elementary school (20%). The participation of the orphans in decision-making is considered good, with a median of 25.5. The bivariate analysis concludes the association between anxiety, age, grade, and decision-making participation (p= 0.024, p= 0.029, p=0.029, respectively).Conclusion: Taken together, attention to orphans, especially adolescents, and their problems are necessary to reduce the health discrepancies within these vulnerable groups. Broader respondents are needed to understand the complete picture of mental health conditions among Indonesian adolescent orphans, including late adolescents.
THALASSEMIA LITERACY: INCREASING KNOWLEDGE OF ORPHAN ADOLESCENTS ON THALASSEMIA Danti Nur Indiastuti; Zahras Azimuth Doman; Nurmawati Fatimah; Mhd Zamal Nasution; Annette d'Arqom
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 8 No. 1 (2024): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v8i1.2024.086-095

Abstract

Thalassemia is the most common monogenic disease in Asia, including Indonesia that causes burdens for the government, patients, and families. As the sixth most non-communicable disease, thalassemia utilized IDR 600 billion in 2022 for more than 300 thousand cases. With, 3.8% of Indonesians carrying a mutation of thalassemia on their globin gene, this economic burden is projected will increase if no actions are taken. On the other hand, child marriage is reported to increase every year, including among orphans. Without proper knowledge and genetic testing on thalassemia, child marriage might contribute to the increasing of thalassemia patients. Thus, increasing knowledge on thalassemia among orphan adolescents is important. This community development uses several methods, including seminar, discussion, book, and poster, targeting the orphan adolescents (n= 40) in Mojokerta, East Java. A questionnaire on thalassemia was used to measure the knowledge, before and after the activity. The results show that the respondents have a moderate knowledge about thalassemia (median= 4 (0-9)), and increase to median=9 (3-10)) after the activities (p< 0.001). Even though overall knowledge is increased, several information including thalassemia is a genetic disease, not similar to blood cancer, not the only type of anemia (Q6), and how to diagnose thalassemia (Q9) still need to be emphasized. Taken together, direct and indirect approaches, such as seminar, discussion, book, and poster are effective in increasing thalassemia knowledge among orphan adolescents. These activities are more effective in targeting late adolescents, compared to early and middle adolescents. However, more effective methods are necessary to target Generation Z who are more familiar with the internet.
PEMBERDAYAAN KADER KESEHATAN TENTANG TANAMAN OBAT BERKHASIAT ANTI HIPERTENSI PADA MASYARAKAT DI DESA KENTONG KECAMATAN GLAGAH KABUPATEN LAMONGAN: PEMBERDAYAAN KADER KESEHATAN TENTANG TANAMAN OBAT BERKHASIAT ANTI HIPERTENSI PADA MASYARAKAT DI DESA KENTONG KECAMATAN GLAGAH KABUPATEN LAMONGAN Fatimah, Nurmawati; Mustika, Arifa; Setiawati, Yuani; D’Arqom, Annette; Purwaningsih, Sri; Rochmanti, Maftuchah; Nur Indiastuti, Danti; Hasanatuludhhiyah, Nurina; Akbar Kurniawan, Mohammad
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 2 (2024): Agustus
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pemberdayaan kader kesehatan dalam program GERMAS melalui Posbindu di Desa Kentong, Kecamatan Glagah, Kabupaten Lamongan bertujuan untuk meningkatkan pengetahuan tentang pemanfaatan tanaman obat yang berkhasiat sebagai anti hipertensi. Tingginya prevalensi pasien hipertensi di daerah tersebut, diduga akibat dari kepatuhan berobat yang rendah, pengetahuan perilaku gaya hidup dan diet yang sehat masih belum optimal, serta minimnya informasi dan pengetahuan tentang pemanfaatan tanaman obat pada pasien hipertensi. Solusi yang ditawarkan untuk menyelesaikan permasalahan tersebut adalah memberikan penyuluhan tentang materi pentingnya mengelola hipertensi dengan baik, pengobatan rutin, perilaku gaya hidup serta diet sehat bagi pasien hipertensi,  sosialisasi tanaman obat berkhasiat sebagai antihipertensi dan demonstrasi pelatihan pembuatan sediaan dari tanaman obat. Metode yang digunakan melalui survei, kuesioner dan penyuluhan penyampaian materi, serta demonstrasi langsung di depan peserta. Ditemukan pada kuesioner pretes bahwa kader belum paham tentang ragam tanaman obat dan pengolahan yang tepat, setelah dilakukan penyuluhan dan demonstrasi terjadi peningkatan pengetahuan dengan para kader mampu menjawab pos tes dengan benar, peserta aktif berdiskusi secara oral, hal tersebut sebagai indikator bahwa peserta antusias dan dapat tercipta kader kesehatan yang mandiri.
Efek Antidiabetik Ekstrak Daun Gendola (Basella rubra L.) Terhadap Kadar Gula Darah Tikus Putih Vita, Angelica Diana; Fatimah, Nurmawati; Murtiwi, Sri
Jurnal Medik Veteriner Vol. 2 No. 2 (2019): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.853 KB) | DOI: 10.20473/jmv.vol2.iss2.2019.127-132

Abstract

Penelitian bertujuan untuk menguji efek antidiabetik ekstrak daun gondola (Basella rubra L.) pada kadar gula darah tikus putih (Rattus norvegicus) yang diinduksi Alloxan. Penelitian ini merupakan penelitian eksperimen dengan menggunakan 35 ekor tikus putih. Tikus tersebut dibagi menjadi lima kelompok perlakuan, yakni: P1; P2; P3; kontrol negatif (K-); dan kontrol positif (K+). Masing-masing kelompok diinduksi menggunakan Alloxan untuk meningkatakan kadar gula darah. Kelompok P1; P2; P3 diberi ekstrak daun gendola dengan dosis 200; 300; 400 mg/kgBB/hari. Kelompok K+ diberi obat glimepirid 0.1 mg/kgBB/hari. Kelompok P1 mengalami penurunan kadar gula darah yang tidak signifikan sebesar 30.14 mg/dL (p-value=0.128); kelompok P2 mengalami penurunan kadar gula darah tidak signifikan sebesar 25.80 mg/dL (p-value=0.159); kelompok P3 mengalami penurunan kadar gula darah yang signifikan sebesar 42.80 mg/dL (p-value=0.043). Kelompok kontrol negatif mengalami peningkatan kadar gula darah sebesar 116.00 mg/dL (p-value=0.084). Kelompok kontrol positif mengalami penurunan kadar gula darah yang signifikan sebesar 21.60 mg/dL (p-value=0.011). Ekstrak daun gendola 400 mg/kgBB/hari dapat menurunkan kadar gula darah tikus dengan perbedaan tidak signifikan apabila dibandingkan dengan obat antidiabetes glimepirid 0.1 mg/kgBB/hari.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Achmad Januar Er Putra Afif Nurul Hidayati Akbar Kurniawan, Mohammad Alpha Fardah Athiyyah Amatullah, Nida' Fahima Annette d’Arqom, Annette Arifa Mustika Bambang Hermanto Damayanti Damayanti Dau, Daniel Dhia Farhan Taufik Dimyati, Sinta Diyah D’Arqom, Annette Farhan Nurdiansyah Finna Permata Putri Herisulistyo, Aldilatama Herwanto, Bambang I Dewa Ayu Sudiari Dewi Indiastuti, Danti Nur Indri Safitri Mukono, Indri Safitri Insyira Rayhana Irsan Izzatul Fithriyah Khaerunnisa, Siti Kusuma Eko Purwantari Linda Dewanti Maftuchah Maftuchah Mhd Zamal Nasution Muchammad Toyib Mukhoirotin Mukhoirotin Nabilah Paramitha Nilamsari, Karina Ayu Nurina Hasanatuludhhiyah Prabowo, Gwenny Ichsan Ratna Sofaria Munir, Ratna Sofaria Sakina Sakina Sri Murtiwi Sri Purwaningsih Sri Purwaningsih Steven Christian Susianto Suhariningsih Suharno, Novianto Edi Sulistiawati Sulistiawati Sutji Kuswarini Sutji Kuswarini Turchan, Agus Vita, Angelica Diana Wening Hapsari William Andrew Isaac Yuani Setiawati Yusuf, Muhtarum Zahras Azimuth Doman