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Phytochemical Screening and Therapeutic Effects of Binahong (Anredera cordifolia (Ten.) Steenis) Leaves Salim, Angeline; Kristanto, Dandy Felix; Subianto, Felicia; Sundah, Janice Evita; Jamaica, Putri Avanny; Angelika, Tiara; Maulida, Nurul Fajry
Indonesian Journal of Life Sciences 2021: IJLS Vol 03 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.721 KB) | DOI: 10.54250/ijls.v3i2.125

Abstract

In this review, the function of secondary metabolites in Binahong (Anredera cordifolia (Ten.) Steenis) leaves were summarized for their therapeutic effects such as antimicrobial activity, anti-inflammatory, wound healing, lowering the blood pressure, and antihyperlipidemic activity as a potential medicinal plant to treat disease. The phytochemical screening of Binahong leaves extracted by using particular solvent showed positive results to the presence of phenolic, steroid, terpenoid, alkaloid, and saponin compounds contained in the extract. The antimicrobial activity is able to disrupt cell membrane activity and inhibit bacterial growth, meanwhile anti-inflammatory ability is able to decrease anti-inflammatory agents level. It also decreases blood pressure by regulation of lipid metabolites, reduction of peripheral resistance, and upregulation of nitric oxide activity. The ethanolic extract of Binahong leaves can reduce fat deposits or layers in the endothelial cells, cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol levels, and decrease the levels of malondialdehyde (MDA formation) from the lipid peroxidation to prevent hyperlipidemia and heart disease.
Upaya Peningkatan Kesadaran Masyarakat dan Deteksi Dini Diabetes Melitus Melalui Edukasi dan Skrining Salsabila, Lyansaputri; Rindarwati, Asti Yunia; Destiani, Dika Pramita; Jamaica, Putri Avanny
Jurnal Pengembangan dan Pengabdian Masyarakat Multikultural Vol 2 No 2: BATIK Agustus 2024
Publisher : Institut Riset dan Publikasi Indonesia (IRPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57152/batik.v2i2.1577

Abstract

Diabetes mellitus (DM) is a metabolic disease caused by a persistent increase in high blood glucose levels due to insufficient insulin production. Diabetes affects individuals of all ages and genders making it one of the most common global causes of death and disease. The most common types of DM are type 1 and type 2, which are generally caused by impaired insulin secretion and/or insulin action. Before an individual develops type 2 diabetes, the individual previously suffered from prediabetes, a condition where blood glucose levels are higher than normal but not yet high enough to be diagnosed as diabetes. The impact of diabetes can be reduced by taking preventative measures for type 2 diabetes and prediabetes through early detection, appropriate treatment and education regarding diabetes. Counseling activities were carried out at the Regional Health Center, Derwati, Rancasari, Bandung, West Java, Indonesia on June 8 2024, from 84 people who took part in the activity, 15% were in the diabetes category and 15% in the prediabetes category. Providing education and good lifestyle recommendations is carried out to increase public awareness and routine compliance with blood sugar control, which is an important action to maintain disease stability and prevent more serious complications.
Skrining dan Edukasi Sebagai Upaya Pengendalian Hipertensi Jamaica, Putri Avanny; Rindarwati, Asti Yunia; Destiani, Dika Pramita; Salsabila, Lyansaputri
Jurnal Pengembangan dan Pengabdian Masyarakat Multikultural Vol 2 No 3: BATIK Desember 2024
Publisher : Institut Riset dan Publikasi Indonesia (IRPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57152/batik.v2i3.1718

Abstract

Hypertension poses significant global challenges and contributes to the rising morbidity and mortality rates associated with cardiovascular diseases, including heart disease and stroke. Commonly referred to as a "silent killer," hypertension frequently presents without significant symptoms, making early detection and appropriate management crucial. This community service program aims to conduct hypertension screening and provide education to enhance awareness and promote preventive measures. The activities were carried out at a integrated service post (Posyandu), involving 62 participants aged between 34 and 81 years. The program included health screenings, which assessed blood pressure and blood glucose levels, as well as educational sessions addressing hypertension risk factors, preventive strategies, and the importance of therapy adherence. Results indicated that 14.5% of participants had normal blood pressure, while 63% fell into the prehypertensive category, 17.7% were classified as stage 1 hypertension, and 4.8% were identified as having stage 2 hypertension. The educational sessions emphasized lifestyle changes and the importance of regular health monitoring to prevent further complications. This program underscores the necessity of continuous health education and promotion in the community to control hypertension and improve overall public health.