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All Journal Sriwijaya Journal of Forensic and Medicolegal Sriwijaya Journal of Internal Medicine
Ilyas Syafiq Darul Ridzuan
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing

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The Role of Understanding the Medicolegal Implications of Occupational Safety and Health (OSH): An Observational Study of Compliance with the Use of Personal Protective Equipment (PPE) among Single Center Laboratory Staff at Indriati Boyolali Hospital Putri, Arum Kusuma; Ilyas Syafiq Darul Ridzuan; Emma Ismawatie; Yulita Maulani; Basuko Agus Wibowo
Sriwijaya Journal of Forensic and Medicolegal Vol. 2 No. 2 (2024): Sriwijaya Journal of Forensic and Medicolegal
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjfm.v2i2.139

Abstract

Introduction: Occupational safety and health (OSH) is a crucial issue in the medical laboratory environment, considering the potential for exposure to various biological and chemical risks. The proper use of personal protective equipment (PPE) is one of the main pillars in mitigating this risk. Understanding the medicolegal implications related to the use of PPE is an important aspect that can influence laboratory staff compliance. This study aims to examine the relationship between understanding medicolegal implications and compliance with the use of PPE among laboratory staff at Indriati Boyolali Hospital. Methods: This study used a cross-sectional observational design. The sample consisted of 120 laboratory staff at Indriati Boyolali Hospital who were selected randomly. Data was collected through structured questionnaires to measure the level of understanding of medicolegal implications and direct observation to assess compliance with PPE use. Data analysis was carried out using descriptive and inferential statistical tests (chi-square test and logistic regression). Results: The research results showed that there was a significant relationship between understanding medicolegal implications and compliance with PPE use (p < 0.05). Laboratory staff with a better understanding of medicolegal implications tend to demonstrate higher levels of compliance in the use of PPE. Other factors such as age, gender, and work experience were also found to influence compliance with PPE use. Conclusion: Understanding medicolegal implications is an important factor that contributes to compliance with the use of PPE among laboratory staff. Comprehensive educational interventions regarding medicolegal aspects of OSH can increase the understanding and awareness of laboratory staff, thereby contributing to improving occupational safety and health in the laboratory environment.
The Dynamics of NS1 Antigen and Platelet Levels in the Acute Phase of Dengue Hemorrhagic Fever Ismawatie, Emma; Ilyas Syafiq Darul Ridzuan; Yulia Ratna Dewi; Sunarti
Sriwijaya Journal of Internal Medicine Vol. 3 No. 1 (2025): Sriwijaya Journal of Internal Medicine
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjim.v2i2.149

Abstract

Introduction: Dengue hemorrhagic fever (DHF) is a significant global health concern, particularly in tropical and subtropical regions. The early diagnosis and effective management of DHF are crucial to reduce morbidity and mortality. The NS1 antigen and platelet count are two key laboratory parameters used in the diagnosis and monitoring of DHF. This study aimed to investigate the dynamics of NS1 antigen and platelet levels during the acute phase of DHF and their correlation with disease severity. Methods: A prospective cohort study was conducted at a tertiary care hospital in Central Java, Indonesia. Patients presenting with suspected DHF were enrolled and followed up during their hospitalization. Blood samples were collected at admission and at regular intervals to measure NS1 antigen levels and platelet counts. Clinical and laboratory data were collected to assess disease severity. Results: A total of 150 patients were included in the study. The majority of patients were adults (median age, 32 years) with a female predominance (58%). The median duration of fever at presentation was 4 days. NS1 antigen levels were significantly higher in patients with DHF compared to those with dengue fever (DF) (p < 0.001). Platelet counts were significantly lower in patients with DHF compared to those with DF (p < 0.001). NS1 antigen levels showed a negative correlation with platelet counts (r = -0.62, p < 0.001). The levels of NS1 antigen and platelet count were also significantly associated with disease severity. Conclusion: The dynamics of NS1 antigen and platelet levels during the acute phase of DHF provide valuable insights into disease pathogenesis and can aid in the early diagnosis and prediction of disease severity. The negative correlation between NS1 antigen and platelet levels suggests a potential role of NS1 in the development of thrombocytopenia in DHF. Further studies are needed to elucidate the exact mechanisms underlying these observations.
Co-Authors Basuko Agus Wibowo Emma Ismawatie Ismawatie, Emma Putri, Arum Kusuma Sunarti Yulia Ratna Dewi Yulita Maulani