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Beyond Hemoglobin: The Effect of Iron Supplementation on Cognitive Function, Academic Achievement, and School Absenteeism in Anemic Indonesian Adolescents – A Randomized Controlled Trial Dewi, Yulia Ratna; Emma Ismawatie; Yulita Maulani; Eko Sumargiyanto
Sriwijaya Journal of Obstetrics and Gynecology Vol. 2 No. 2 (2024): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v2i1.106

Introduction: Iron deficiency anemia (IDA) is a pervasive public health challenge, affecting over one-third of adolescent girls in Indonesia. While the hematological consequences are known, there is a critical lack of high-quality trial data on the functional impact—including cognition and educational outcomes—in this specific population. Methods: We conducted a 12-week, double-blind, placebo-controlled, parallel-group randomized controlled trial in Klaten, Indonesia. We enrolled 200 anemic (Hemoglobin [Hb] < 12 g/dL) female senior high school students, aged 15-18. Participants were randomized (1:1) to receive either 60 mg of elemental iron (as ferrous sulfate) or an identical placebo, taken daily. Primary outcomes were the change in Hb (hematological) and cognitive processing speed (functional), measured by the Digit Symbol Substitution Test (DSST). Secondary outcomes included anemia prevalence, serum ferritin, academic achievement (change in school-recorded grades), and school absenteeism (days missed). Results: At 12 weeks, the iron group demonstrated a significantly greater increase in mean Hb compared to the placebo group (2.7 g/dL vs. 1.4 g/dL; mean difference: 1.3 g/dL, 95% CI: 0.9-1.7, p < 0.001). Anemia prevalence was halved (20% vs. 40%, p = 0.02). Functionally, the iron group showed a marked improvement in DSST scores (mean change: +8.5 vs. +2.1; mean difference: 6.4, 95% CI: 4.1-8.7, p < 0.001), a significant improvement in academic grades (mean difference: +1.6 points, 95% CI: 0.5-2.7, p = 0.005), and a 61% reduction in mean days of school missed (1.2 vs. 3.1 days; mean difference: -1.9 days, 95% CI: -2.8 to -1.0, p < 0.001). Adverse events were mild and not significantly different between groups. Conclusion: Daily iron supplementation in anemic adolescents robustly improves hematological status and, critically, translates these gains into significant, tangible improvements in cognitive function, academic performance, and school attendance. These findings provide strong, multi-domain evidence to support the scaling of public health anemia interventions.

The Impact of Cholesterol on Stroke Outcomes: A Cross-Sectional Analysis in Central Java Maulani, Yulita; Toirov Abdukhamid Suvonovich; Emma Ismawatie; Asri Wulandari
Sriwijaya Journal of Neurology Vol. 2 No. 2 (2024): Sriwijaya Journal of Neurology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjn.v2i1.150

Introduction: Stroke remains a leading cause of mortality and morbidity globally, with variations in subtypes and risk factors observed across populations. The role of cholesterol in stroke, particularly its association with ischemic and hemorrhagic subtypes, continues to be investigated. This study aimed to examine the relationship between cholesterol levels and stroke outcomes in a Central Javanese population. Methods: A cross-sectional study was conducted at hospitals in Central Java, Indonesia. Data were collected from medical records of patients diagnosed with ischemic or hemorrhagic stroke between January and December 2022. Demographic information, stroke subtype, and cholesterol levels were analyzed. Statistical tests were employed to assess the association between cholesterol and stroke outcomes. Results: The study included 68 patients (34 ischemic, 34 hemorrhagic). The majority of hemorrhagic stroke patients were female (52.9%), while ischemic stroke patients were predominantly male (64.7%). The mean cholesterol level for hemorrhagic stroke patients was 202.59 mg/dL, and for ischemic stroke patients, it was 190.26 mg/dL. Statistical analysis revealed no significant association between cholesterol levels and stroke subtype (p > 0.05). Conclusion: The findings suggest that cholesterol levels may not be a primary determinant of stroke subtype in this Central Javanese population. Further research is warranted to explore other potential risk factors and their interplay with cholesterol in influencing stroke outcomes.

Edukasi dan Pemeriksaan Dini Gaya Hidup Sehat Melalui Pengendalian Gula Darah Yulita Maulani; Emma Ismawatie; Edy Purwanto; Laela Siti Musrikatun
JURNAL PENGABDIAN KESEHATAN Vol. 3 No. 2 (2025): MEI
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/jupengkes.v3i2.1329

Diabetes Mellitus (DM) is a chronic metabolic condition characterized by elevated blood sugar levels, often attributed to unhealthy lifestyles and insufficient early detection. This activity aimed to enhance public knowledge and facilitate early blood sugar screening at Solo Grand Mall, Surakarta City, as a proactive promotional and preventive measure against the increasing prevalence of DM. The methodology employed in this community service initiative included educational presentations on healthy lifestyles and blood sugar control, alongside free blood sugar tests for interested mall visitors, with support from PT Edsa Setia Abadi. The outreach and screening activities garnered significant enthusiasm from participants, evidenced by the large number of active attendees. This initiative successfully imparted crucial knowledge regarding the importance of healthy living and early DM detection to the community of Solo and its surrounding areas. It is hoped that following this event, the public will apply the acquired knowledge in their daily lives. Furthermore, the sustained continuation of educational programs and regular screenings, supported by various stakeholders, is essential to effectively prevent and control DM.

Pemeriksaan Tekanan Darah sebagai Upaya Preventif Kesehatan Masyarakat untuk Meningkatkan Kesadaran Pola Hidup Sehat Jimat, Resi Tondho; Emma Ismawatie; Yulita Maulani; Arum Kusuma Putri; Rahmayani Agustin Nanda Kusuma; Rudiharto
JURNAL PENGABDIAN KESEHATAN Vol. 3 No. 2 (2025): MEI
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/jupengkes.v3i2.1332

Hypertension is one of the most common non-communicable diseases that often presents without symptoms but carries a high risk of severe complications such as heart disease and stroke. Preventive and promotive efforts, such as health education and regular blood pressure screening, play a crucial role in increasing public awareness of healthy lifestyles. This community service activity was conducted in Jayan Village, Boyolali, through educational sessions and health screenings involving local residents as participants. The results showed that 81% of participants were identified as having hypertension at various levels. This program successfully improved community understanding of early detection of high blood pressure and encouraged lifestyle modifications. Routine blood pressure checks proved to be an effective preventive strategy for controlling hypertension at the community level.

Diabetes Mellitus, Blood Sugar Levels, Healthy Lifestyle Putri, Arum Kusuma; Emma Ismawatie; Yulia Ratna Dewi; Laela Siti Musrikatun
JURNAL PENGABDIAN KESEHATAN Vol. 3 No. 2 (2025): MEI
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/jupengkes.v3i2.1336

Diabetes Mellitus (DM) is non-communicable diseases (NCDs) that is a problem in the world. DM is a chronic metabolic disorder characterized by high-blood sugar levels. Support a healthy lifestyle with Early detection of DM and checking the current blood sugar (GDS). Uncontrolled GDS levels will cause complications in the body's organs. The method used is socialization with lecturer and discussion as well as checking the current blood sugar (GDS) at Balai RW 3 Dukuh, Ngemplak. The number of participants in this community service was attended by 11 participants. The results of this service 82% normal, 18% upnormal and average of 148.36 mg/dL (normal GDS, <200mg/dL). The result if education on management of DM, the community was anthusiastic and able to answer several questions during the discussion session.

Gerakan Cegah Diabetes: Pemeriksaan Gula Darah dan Sosialisasi Pola Hidup Sehat Putri, Arum Kusuma; Emma Ismawatie; Yulia Ratna Dewi; Laela Siti Musrikatun
JURNAL PENGABDIAN KESEHATAN Vol. 4 No. 1 (2025): NOVEMBER
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/jupengkes.v4i1.1372

Diabetes Mellitus (DM) is non-communicable diseases (NCDs) that is a problem in the world. DM is a chronic metabolic disorder characterized by high-blood sugar levels. Support a healthy lifestyle with Early detection of DM and checking the current blood sugar (GDS). Uncontrolled GDS levels will cause complications in the body's organs. The method used is socialization with lecturer and discussion as well as checking the current blood sugar (GDS) at Balai RW 3 Dukuh, Ngemplak. The number of participants in this community service was attended by 11 participants. The results of this service 82% normal, 18% upnormal and average of 148.36 mg/dL (normal GDS, <200mg/dL). The result if education on management of DM, the community was anthusiastic and able to answer several questions during the discussion session.

EFFECT OF EDTA AND 3.8% SODIUM CITRATE ON BLOOD SEDIMENTATION RATE BY WESTERGREN METHOD WITH 0.86% NACL Rahmayani Agustin Nanda Kusuma; Emma Ismawatie; Yulia Ratna Dewi
Medical Journal of Nusantara Vol. 4 No. 3 (2025): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v4i3.1685

Background: The erythrocyte sedimentation rate (ESR) is a hematological test used to detect inflammatory processes and blood disorders. ESR values can be influenced by the type of anticoagulant used. Objective: To compare ESR values in venous blood samples using EDTA and 3.8% sodium citrate anticoagulants with the Westergren method modified by the addition of 0.86% NaCl. Methods: This study employed an observational analytical approach with a cross-sectional design, conducted at the Clinical Pathology Laboratory of Politeknik Indonusa Surakarta. A total of 32 venous blood samples were examined using both anticoagulants. Data were analyzed statistically using the Mann–Whitney test. Results: The mean ESR value in samples with EDTA anticoagulant was 18.3 mm/h, while that in samples with 3.8% sodium citrate was 13.1 mm/h. Statistical analysis yielded a p-value of 0.014 (p < 0.05), indicating a significant difference between the two groups. This difference may be attributed to the chemical properties and osmolarity of each anticoagulant, which affect erythrocyte rouleaux formation. Conclusions: The type of anticoagulant significantly affects ESR results. 3.8% sodium citrate remains the preferred anticoagulant for the Westergren method according to standard protocols, without the addition of 0.86% NaCl dilution

GAMBARAN TIPE ANEMIA PADA IBU HAMIL BERDASARKAN NILAI INDEKS ERITROSIT DI RSIA RESTU IBU TAHUN 2022 Emma Ismawatie; Resi Tondho Jimat; Yulia Ratna Dewi; Okti Purwaningsih
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 7 No. 1 (2023): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v7i1.196

Anemia in pregnant women is a global problem that impacts both mother and fetus. Anemia in pregnancy is associated with maternal morbidity and is an indirect cause of maternal death in the entire population of pregnant women. Classification of anemia based on the erythrocyte index value is divided into normochromic normocytic, normochromic macrocytic, hypochromic microcytic and hypochromic macrocytic anemia. The erythrocyte index values are divided into Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH) and Mean Corpuscular Hemoglobin Concentration (MCHC). The aim of the research is to describe the types of anemia in pregnant women based on the erythrocyte index value at RSIA Restu Ibu Sragen in 2022. This research uses a quantitative descriptive research type with a retrospective approach. The research sample was 51 medical records of pregnant women who experienced anemia at RSIA Restu Ibu Sragen in January-December 2022 using purposive sampling. The materials and tools used were secondary data from laboratory examination results of pregnant women diagnosed with anemia which included hematocrit, hemoglobin, index erythrocytes (MCV, MCH, and MCHC), Microsoft Excel and SPSS Version 21 software. Data analysis used analysis univariate. The results of the study concluded that pregnant women who experienced anemia at RSIA Restu Ibu Sragen were aged 21-34 years with a third trimester pregnancy and were primigravida. Based on the erythrocyte index, normocytic anemia was normochromic in 18 people (35.3%), microcytic hypochromic anemia in 20 people (39.2%), and macrocytic hypochromic anemia in 13 people (25.5%). So it can be said that most pregnant women experience microcytic hypochromic anemia.

PERAN FAKTOR GENETIK DALAM PERKEMBANGAN KANKER PAYUDARA PADA WANITA USIA 30–60 TAHUN Yulita Maulani; Emma Ismawatie; Resi Tondho Jimat; Arum Kusuma Putri
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.263

Breast cancer is among the most prevalent cancers in women and a leading cause of mortality worldwide. This study aims to analyze the role of genetic factors in the incidence of breast cancer among women aged 30–60 years. The study employed an analytical observational design with a cross-sectional approach, and participants were selected through purposive sampling. Data were collected from medical records and analyzed using the chi-square test. The results revealed a significant association between genetic factors—particularly a family history of breast cancer—and the occurrence of the disease. Other contributing factors included age at menarche, hormonal contraceptive use, and lifestyle habits. These findings underscore the importance of early detection and awareness of genetic risk factors to improve breast cancer prevention and management strategies.

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