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All Journal Jurnal Ilmiah Manusia dan Kesehatan Narra J
Harrika, Fenny
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Humanities Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Giant bronchopleural fistula and empyema in a tuberculosis patient with diabetes mellitus: Vista from a high tuberculosis burden country in Southeast Asia Yanti, Budi; Hadi, Saiful; Harrika, Fenny; Shehzad, Aamir
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.81

Abstract

Bronchopleural fistula is a pathological tract between the bronchial tree and the pleural space, which can be life-threatening due to tension pneumothorax. It is a rare complication in tuberculosis cases with highly variable in clinical manifestations and persistent air leaks which might lead to complications such as empyema. Herein, we present a tuberculosis and diabetic patient complicated with giant bronchopleural fistula and empyema. A 48-year-old man presented with shortness of breath for two weeks and cough with phlegm for two months. The patient was a smoker with severe Brinkman Index and diabetes. Physical examination revealed hyper resonant percussion and vesicular diminished on the left hemithorax. Laboratory results indicated the patient had anemia, leukocytosis, and hypoalbuminemia. GeneXpert sputum confirmed the presence of Mycobacterium tuberculosis and chest X-ray indicated a collapsed left lung. The patient was diagnosed with left secondary spontaneous pneumothorax, pulmonary tuberculosis, and diabetes. The patient was treated with chest tube drainage and anti-tuberculosis drugs. There was no improvement based on serial chest X-ray, and empyema appeared from the chest tube. CT-scan showed tuberculosis lesion, the collapsed of the left lung and fistula in segments 7-8 inferior lobe. Exploratory thoracostomy was performed, in which a giant bronchopleural fistula was detected and then repaired with BioGlue surgical adhesive. Unfortunately, the thoracostomy led to extensive subcutaneous emphysema and was treated by cervical mediastinotomy. The drainage was unable to be removed, and the patient was discharged with Heimlich-type drainage valves on day 28 of treatment. The empyema fluid was cultured and revealed Staphylococcus haemolyticus. This case highlights that tuberculosis could cause a bronchopleural fistula and empyema may occur secondary to late diagnosis that needs immediate surgery.
A choledochal cyst type IVa in a child treated with Roux-en-Y hepaticojejunostomy Yusuf, Sulaiman; Nuriyanto, Alivia R.; Nadia, Nurul; Muntadhar, Muntadhar; Muzakkir, Yumna; Susanti, Nurhayani D.; Al-shather, Zain; Harrika, Fenny
Narra J Vol. 3 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i2.201

Abstract

A choledochal cyst is a bile duct anomaly that disrupts the transportation of bile from the liver to the gallbladder and small intestine. Choledochal cysts are rare, occurring in approximately one out of every 100,000 to 150,000 children in Western countries, with a girls-to-boys ratio of 4:1. Immediate surgery to excise the cyst and construct a biliary-enteric continuity is necessary to treat this condition. This case-report aimed to present a child with choledochal cyst type IVa who underwent a Roux-en-Y hepaticojejunostomy. A 3-year-11-month-old girl with an abdominal mass experienced jaundice, nausea, and vomiting over the past two years, which worsened in the last month. Abdominal ultrasonography indicated intrahepatic biliary dilatation. Abdominal computed tomography (CT) scan results confirmed a choledochal cyst type IVa, characterized by fusiform cyst dilatation at the bilateral intrahepatic bile duct, common hepatic duct, cystic duct, and common bile duct. The cyst exerted pressure on the pancreas and small intestine. Before the surgery, the patient was treated with ceftriaxone 100 mg/kg/day and gentamicin 5 mg/kg/day. Roux-en-Y hepaticojejunostomy was performed, involving the complete excision of the extrahepatic bile duct to reconstruct the biliary system. During the surgery, a retroperitoneal cyst measuring 20 cm x 10 cm with a volume of 200 cc was discovered. Following the surgery, the patient showed clinical improvement. Patient follow-ups indicated that no complications such as wound infection, acute pancreatitis, and the formation of pancreatic or biliary fistula occurred. This case highlights that Roux-en-Y hepaticojejunostomy proves to be an effective surgical approach for managing choledochal cyst type IVa in children, helping to prevent further complications.
Pengaruh Kadar Glukosa Darah Puasa Pada Mencit Yang Di Induksi Minyak Jelantah Khairunnisa; Sahputri, Juwita; Harrika, Fenny
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 6 No. 1 (2023): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v6i1.1969

Abstract

Minyak jelantah dapat berdampak pada tubuh diantaranya, terdapat kandungan asam lemak yaitu TFA (Trans Fatty Acid), dengan konsumsi yang berlebihan dapat meningkatkan risiko penyakit kardiovaskular, obesitas dan diabetes mellitus. Dilihat masih banyak orang yang menggunakan minyak jelantah yang memiliki kandungan asam lemak trans yang bisa meningkatkan kadar glukosa darah. Tujuan dilakukan penelitian ini utuk mengetahui pengaruh minyak jelantah terhadap kadar glukosa darah puasa mencit (Mus Musculus L). Penelitian ini merupakan true experimental dengan metode post test only control group design. Sampel penelitian ini adalah 24 ekor mencit (Mus Musculus L) jantan yang dibagi menjadi 4 kelompok. Hasil rerata pemerikasan kadar glukosa darah puasa pada setiap kelompok kontrol yang diberikan minyak goreng tanpa pemanasan 116,3 mg/dl, perlakuan Ⅰ minyak goreng dengan pemanasan 4 kali 95,3 ml/dl, perlakuan Ⅱ minyak goreng dengan pemanasan 8 kali 73,3 ml/dl, dan perlakuan Ⅲ minyak goreng dengan pemanasan 12 kali 83,5 mg/dl. Hasil uji banding menggunakan uji One Way ANOVA dengan nilai p. value sebesar 0,003 (p>0,05) dan hasil uji LSD memperlihatkan terdapat perbedaan antara kelompok kontrol dan PⅡ dengan nilai p=0,004 (p>0,05). Kesimpulan yang didapatkan dari penelitian ini adalah terdapat perbedan bermakna kadar glukosa darah puasa pada mencit yang di induksi minyak goreng tanpa pemanasan dengan kadar glukosa darah puasa mencit yang di induksi minyak jelantah dengan 8 kali pemanasan
Co-Authors Al-shather, Zain Khairunnisa Muntadhar, Muntadhar Muzakkir, Yumna Nadia, Nurul Nuriyanto, Alivia R. Sahputri, Juwita Saiful Hadi Shehzad, Aamir Sulaiman Yusuf Susanti, Nurhayani D. Yanti, Budi