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Monkeypox: Immune response, vaccination and preventive efforts Ophinni, Youdiil; Frediansyah, Andri; Sirinam, Salin; Megawati, Dewi; Stoian, Ana M.; Enitan, Seyi S.; Akele, Richard Y.; Sah, Ranjit; Pongpirul, Krit; Abdeen, Ziad; Aghayeva, Sevda; Ikram, Aamer; Kebede, Yohannes; Wollina, Uwe; Subbaram, Kannan; Koyanagi, Ai; Al Serouri, Abdulwahed; Nguendo-Yongsi, H. Blaise; Edwards, Jeffrey; Sallam, Dina E.; Khader, Yousef; Viveiros-Rosa, Sandro G.; Memish, Ziad A.; Amir-Behghadami, Mehrdad; Vento, Sandro; Rademaker, Marius; Sallam, Malik
Narra J Vol. 2 No. 3 (2022): December 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i3.90

Abstract

Infectious threats to humans are continuously emerging. The 2022 worldwide monkeypox outbreak is the latest of these threats with the virus rapidly spreading to 106 countries by the end of September 2022. The burden of the ongoing monkeypox outbreak is manifested by 68,000 cumulative confirmed cases and 26 deaths. Although monkeypox is usually a self-limited disease, patients can suffer from extremely painful skin lesions and complications can occur with reported mortalities. The antigenic similarity between the smallpox virus (variola virus) and monkeypox virus can be utilized to prevent monkeypox using smallpox vaccines; treatment is also based on antivirals initially designed to treat smallpox. However, further studies are needed to fully decipher the immune response to monkeypox virus and the immune evasion mechanisms. In this review we provide an up-to-date discussion of the current state of knowledge regarding monkeypox virus with a special focus on innate immune response, immune evasion mechanisms and vaccination against the virus.
Nurses’ experience of using platform for phlebitis assessment based on telemedicine consultation system: a qualitative descriptive study Thangkratok, Pramote; Pongpirul, Krit; Sriratanaban, Jiruth
Jurnal Ners Vol. 20 No. 2 (2025): VOLUME 20 ISSUE 2 MAY 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v20i2.60596

Abstract

Introduction: Current methods for assessing phlebitis rely on nurses' experiences. Integrating advanced systems, such as a Clinical Decision Support System and a Telemedicine Consultation System, is essential for more comprehensive and expert-driven diagnosis and treatment recommendations. This study explored nurses' experiences using a platform for phlebitis assessment based on a telemedicine consultation system. Methods: A qualitative study based on constructivist theory was conducted using focus group interviews with 12 registered nurses recruited from a community hospital in Thailand, between November 2022 and March 2023. The interviews were then recorded and transcribed. Data analysis followed Miles and Huberman's framework, which comprised three stages: (1) data reduction, involving the selection, organization, and coding of key data; (2) data display, structuring the data into themes to identify patterns; and (3) conclusion drawing and verification to ensure accuracy and validity through systematic comparison and cross-checking. Results: Four themes emerged: accuracy, referring to the precision of the assessments; feasibility, which pertains to how practical the system is for daily clinical use; propriety, concerning ethical and professional considerations such as patient confidentiality and alignment with nursing practices; and utility, evaluating the overall usefulness and value of the platform in enhancing assessment efficiency. Conclusions: The platform for phlebitis assessment based on the telemedicine consultation system can accurately evaluate and diagnose phlebitis. It is suitable for practical use in clinical settings and can improve patient care quality.