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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Medica Hospitalia Journal of Social Research Surabaya Biomedical Journal Surabaya Biomedical Journal
Andisari, Hendrata Erry
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Concomitant Colon Adenocarcinoma And Tuberculous Lymphadenitis Arya Abisatya, Albertus Magnus; Prameswari, Ajeng Andini; Fauzi, Agung Rahmat; Febrianto, Aji Pratama; Nugroho, Alexander Steven; Andisari, Hendrata Erry; Harijono, Pandu; Yudadi, Redemptus
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.1007

Abstract

BACKGROUND : Colon involvement in tuberculosis infection is a rare event. The coexistence of colon carcinoma and tuberculous lesions of the colon is less frequently reported. Carcinoma and tuberculosis of the colon can occur at the same site or at different sites. The occurrence of two pathologies at the same site is much less common. CASE PRESENTATION : A 52 year old woman complained of difficulty defecating, an enlarged stomach, pain and decreased appetite and weight loss within one month. On clinical examination, the abdomen appeared convex, slightly distended, and tenderness in the left lower iliac quadrant. Radiological examination supported the diagnose of partial obstructive ileus. The patient was diagnosed with adenocarcinoma of the ascending colon until the hepatic flexura was confirmed through surgery and histopathological examination. On histopathological examination, adenocarcinoma of the colon was found to coexistence with tuberculous lymphadenitis of the colon. CONCLUSION : The etiological and pathophysiological relationship between tuberculous lymphadenitis and colon cancer is still under debate, but surgeons need to be aware of this occurrence, to choose treatment and avoid post-operative worsening.
PENGARUH LATIHAN RENANG INTENSITAS SUBMAKSIMAL TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH BETINA KELOMPOK TERLATIH DAN TIDAK TERLATIH Alexander, Michael; Dagradi, Eric Mayo; Andisari, Hendrata Erry
Surabaya Biomedical Journal Vol 4 No 1 (2024): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v4i1.118

Abstract

Olahraga adalah kegiatan fisik yang dilakukan untuk meningkatkan kesehatan tubuh. Dengan meningkatnya jumlah masyarakat yang berolahraga, penting untuk memahami batasan intensitas olahraga yang dilakukan. Intensitas olahraga yang melampaui kemampuan tubuh akan menyebabkan munculnya stres oksidatif. Stres oksidatif akan menimbulkan berbagai masalah fisiologis tubuh, termasuk metabolisme glukosa. Jenis penelitian adalah eksperimental laboratoris. Tikus putih (Rattus norvegicus) betina galur Wistar usia 2 bulan dengan berat badan 180-200 gram dikelompokkan ke dalam 5 kelompok melalui teknik random sampling. K1 merupakan kontrol, K2 diberi latihan setiap hari selama 2 minggu, K3 diberi latihan sekali seminggu selama 2 minggu, K4 diberi latihan setiap hari selama 2 minggu, dan K5 diberi latihan sekali seminggu selama 2 minggu. Semua kelompok setelahnya diistirahatkan selama 1 minggu. K1, K2, dan K3 tidak diberi intervensi. K4 dan K5 diberi intervensi latihan submaksimal 85% rerata waktu tenggelam pertama. Penelitian diterminasi dan dilakukan pengambilan sampel untuk pengujian kadar glukosa darah acak. Hasil kadar glukosa darah acak diolah statistik dengan uji parametrik one-way Anova dan uji post hoc LSD. Hasil kadar glukosa darah (K1) 127,8 mg/dL, (K2) 133,4 mg/dL, (K3) 186,4 mg/dL, (K4) 160,6 mg/dL, dan (K5) 140,6 mg/dL. Uji one-way Anova menunjukkan perbedaan signifikan (p<0,05). Uji post hoc LSD menunjukkan tidak ada perbedaan bermakna antara kelompok terlatih dengan intervensi dan tidak terlatih dengan intervensi (p>0,05). Intervensi latihan submaksimal setelah istirahat satu minggu pada kelompok terlatih dan tidak terlatih dengan latihan submaksimal tidak memiliki pengaruh terhadap kadar glukosa darah tikus putih (Rattus norvegicus) betina galur Wistar.
A Case Report of Female Systemic Lupus Erythematosus and Cerebral Lupus as The Complication : Diagnosis and Treatment Darmanto, Stefani Irene; Pitaloka, Sherina Ayu; Fauzia, Silvia Reynata; Ayu, Sonia Kartika; Fajrina, Soraya Nur; Andisari, Hendrata Erry; Suryajaya, I Wayan
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 3 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i3.1178

Abstract

BACKGROUND : Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that affects multiple systems in the body. Because clinical manifestations can appear in different organs, the complications are diverse and can be quite severe, one of which is cerebral lupus or neuropsychiatric systemic lupus erythematosus (NPSLE). It includes neurological and psychiatric syndromes in SLE patients where other causes have been ruled out. We reported a case of SLE manifestation with cerebral complication involvement. AIMS : This case report aims to provide insights and expect to offer an understanding into the clinical presentation, diagnosis, and management of a patient with cerebral lupus. CASE PRESENTATION : 18-year-old Indonesian woman with complaint of sudden seizure was referred to the Emergency Unit of Dr. Ramelan Naval Central Hospital Surabaya. She had previously been diagnosed with SLE back in 2022 and consistently does a monthly checkup in the internal medicine clinic at Dr. Ramelan Naval Central Hospital Surabaya. Initial examinations revealed signs of infection, slight electrolyte imbalances, and a flare phase of SLE, but no abnormalities in imaging tests. She received initial treatments of loading phenytoin along with mecobalamin injection, vitamin B6, methamizole, and cefobactam. Over the course of her hospital stay, with no further seizures, she was discharged with medication for continued treatment and a scheduled follow-up. CONCLUSION : This case of cerebral lupus is rare. SLE can damage the blood brain barrier (BBB), causing neuropsychiatric complications.
PENGARUH LATIHAN RENANG INTENSITAS SUBMAKSIMAL TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH BETINA KELOMPOK TERLATIH DAN TIDAK TERLATIH Alexander, Michael; Dagradi, Eric Mayo; Andisari, Hendrata Erry
Surabaya Biomedical Journal Vol. 4 No. 1 (2024): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v4i1.118

Abstract

Olahraga adalah kegiatan fisik yang dilakukan untuk meningkatkan kesehatan tubuh. Dengan meningkatnya jumlah masyarakat yang berolahraga, penting untuk memahami batasan intensitas olahraga yang dilakukan. Intensitas olahraga yang melampaui kemampuan tubuh akan menyebabkan munculnya stres oksidatif. Stres oksidatif akan menimbulkan berbagai masalah fisiologis tubuh, termasuk metabolisme glukosa. Jenis penelitian adalah eksperimental laboratoris. Tikus putih (Rattus norvegicus) betina galur Wistar usia 2 bulan dengan berat badan 180-200 gram dikelompokkan ke dalam 5 kelompok melalui teknik random sampling. K1 merupakan kontrol, K2 diberi latihan setiap hari selama 2 minggu, K3 diberi latihan sekali seminggu selama 2 minggu, K4 diberi latihan setiap hari selama 2 minggu, dan K5 diberi latihan sekali seminggu selama 2 minggu. Semua kelompok setelahnya diistirahatkan selama 1 minggu. K1, K2, dan K3 tidak diberi intervensi. K4 dan K5 diberi intervensi latihan submaksimal 85% rerata waktu tenggelam pertama. Penelitian diterminasi dan dilakukan pengambilan sampel untuk pengujian kadar glukosa darah acak. Hasil kadar glukosa darah acak diolah statistik dengan uji parametrik one-way Anova dan uji post hoc LSD. Hasil kadar glukosa darah (K1) 127,8 mg/dL, (K2) 133,4 mg/dL, (K3) 186,4 mg/dL, (K4) 160,6 mg/dL, dan (K5) 140,6 mg/dL. Uji one-way Anova menunjukkan perbedaan signifikan (p<0,05). Uji post hoc LSD menunjukkan tidak ada perbedaan bermakna antara kelompok terlatih dengan intervensi dan tidak terlatih dengan intervensi (p>0,05). Intervensi latihan submaksimal setelah istirahat satu minggu pada kelompok terlatih dan tidak terlatih dengan latihan submaksimal tidak memiliki pengaruh terhadap kadar glukosa darah tikus putih (Rattus norvegicus) betina galur Wistar.
Hubungan Antara Lama Hemodialisis Dengan Red Cell Distribution Width (RDW) Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis di Rumah Sakit Pusat Angkatan Laut Dr. Ramelan Surabaya Semara, Putu Bagus Aditya Putra; Herjunianto2, Herjunianto; Andisari, Hendrata Erry
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i9.16334

Abstract

Penyakit Ginjal Kronis (PGK) merupakan masalah kesehatan yang makin berkembang secara global dan membutuhkan terapi pengganti ginjal. Red cell Distribution Width (RDW) merupakan suatu penanda kuantitatif dari variabilitas ukuran eritrosit. Peningkatan RDW menandakan adanya peningkatan variasi ukuran sel darah merah. Penelitian bertujuan untuk mengetahui hubungan antara lama hemodialisis dengan peningkatan Red Cell Distribution Width (RDW) pasien penyakit ginjal kronis yang menjalani hemodialisis di RSPAL Dr. Ramelan Surabaya. Penelitian ini menggunakan metode cross sectional dengan desain penelitian observasional analitik. Teknik pengambilan sampel adalah purposive sampling dengan jumlah sampel 64 pasien PGK yang menjalani HD di RSPAL Dr. Ramelan Surabaya. Pengambilan data menggunakan data sekunder yaitu rekam medis. Analisis data menggunakan uji korelasi Pearson untuk mengetahui hubungan kedua variabel. Hasil Penelitian menunjukan 64 pasien memenuhi kriteria inklusi, terdiri dari laki-laki 39(61%) orang dan perempuan 25(39%) orang, dengan rerata umur 53,68±9,54 tahun, rerata lama hemodialisis yang dijalani pasien adalah 10,22±12,29 bulan, dan rerata nilai RDW_CV adalah 15,13±2,36%. Dari hasil uji korelasi Pearson diperoleh koefisien korelasi 0,046 dengan nilai signifikansi (p) = 0,715. Nilai signifikansi (p) 0,715 > (α) 0,05 menunjukan tidak ada hubungan signifikan antara lama hemodialisis dengan peningkatan RDW pasien PGK yang menjalani HD di RSPAL Dr. Ramelan Surabaya. Dari penelitian ini disimpulkan bahwa, tidak didapatkan korelasi antara lama HD dengan RDW pasien PGK yang menjalani HD. Nilai RDW pasien PGK yang mejalani HD didapatkan rerata yaitu 15,13%. Lama HD yang dilaksanakan pasien PGK di RSPAL Dr. Ramelan Surabaya didapatkan rerata yaitu 10,22 bulan.
Relationship of Triglyceride Levels with the Incidence of Acute Coronary Syndrome in Patients with Type 2 Diabetes Mellitus at RSPAL Dr. Ramelan Surabaya Pakungwati, Tan Wulan; Andisari, Hendrata Erry; Mu’minin, Amiril
Journal of Social Research Vol. 5 No. 4 (2026): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i4.3085

Abstract

Type 2 Diabetes Mellitus (DM) is a major global health issue with increasing prevalence, including in Indonesia, where it significantly contributes to cardiovascular diseases such as Acute Coronary Syndrome (ACS). This study investigates the relationship between triglyceride levels and ACS occurrence in Type 2 DM patients at RSPAL Dr. Ramelan Surabaya. The objective is to explore triglyceride distribution, examine its relationship with ACS, and assess age and gender variations in ACS incidence. Using a cross-sectional observational design, secondary data from the medical records of 92 patients were analyzed. The study found that a high percentage of patients had lipid metabolism disorders, with most exhibiting normal triglyceride levels. The distribution of ACS events revealed that APTS was most prevalent, followed by IMA-EST. Spearman correlation tests showed no statistically significant relationship between triglyceride levels and ACS occurrence (p > 0.05). However, the study indicated that other multifactorial risk factors, such as age, gender, and lifestyle factors, played a more crucial role in the incidence of ACS in Type 2 DM patients. This study suggests that while triglyceride levels alone may not serve as a significant predictor, they could be useful in conjunction with other risk factors for early detection and prevention strategies in clinical settings. Further research is needed to explore causality and develop more effective treatment protocols.
The Relationship of HbA1c Levels with Symptoms of Gastroesophageal Reflux Disease (GERD) in Type 2 Diabetes Mellitus Patients at Prof. Dr. Soekandar Mojokerto Hospital Shafwina Althaf, Aisha; Andisari, Hendrata Erry; Handajani, Fitri
Journal of Social Research Vol. 5 No. 4 (2026): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i4.3086

Abstract

This study aims to investigate the relationship between HbA1c levels and the occurrence of gastroesophageal reflux disease (GERD) symptoms in patients with Type 2 diabetes mellitus (T2DM) at Prof. Dr. Soekandar Hospital, Mojokerto. The prevalence of GERD in diabetic patients, particularly those with poor glycemic control, is a growing concern globally. The primary objective was to determine whether varying HbA1c levels correlate with the severity of GERD symptoms, as measured using the GERD-Q score. A cross-sectional observational design was employed, with data collected through HbA1c measurements and GERD-Q questionnaires from 52 patients with T2DM. The study utilized both univariate and bivariate analyses, including chi-square tests, to evaluate the relationship between glycemic control and GERD symptoms. The results indicated a significant association between higher HbA1c levels and increased GERD prevalence, with 88.9% of patients in the uncontrolled HbA1c group exhibiting GERD symptoms. The chi-square test revealed a significant p-value of <0.001, confirming a strong correlation between poor glycemic control and GERD incidence. This study highlights the importance of glycemic control in reducing the risk of gastrointestinal complications, particularly GERD, in patients with T2DM. Further research is needed to explore the pathophysiological mechanisms underlying this relationship and to develop targeted clinical interventions.
Co-Authors Arya Abisatya, Albertus Magnus Ayu, Sonia Kartika Darmanto, Stefani Irene Eric Mayo Dagradi Fajrina, Soraya Nur Fauzi, Agung Rahmat Fauzia, Silvia Reynata Febrianto, Aji Pratama Handajani, Fitri Harijono, Pandu Herjunianto2, Herjunianto Michael Alexander Mu’minin, Amiril Nugroho, Alexander Steven Pakungwati, Tan Wulan Pitaloka, Sherina Ayu Prameswari, Ajeng Andini Semara, Putu Bagus Aditya Putra Shafwina Althaf, Aisha Suryajaya, I Wayan Yudadi, Redemptus