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Uji Efektivitas Analgetik Dekokta Herba Rumput Bambu (Lophatherum Gracile Brongn.) Terhadap Mencit Putih Jantan (Mus Musculus) Siti Aisyah Tanjung; M.Gunawan; Safriana Safriana
VitaMedica : Jurnal Rumpun Kesehatan Umum Vol. 2 No. 3 (2024): Juli : VitaMedica : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/vitamedica.v2i3.114

Abstract

Analgesics are compounds that in therapeutic doses relieve or suppress pain, without having general anesthetic action. Traditionally, the herb bamboo grass (Lophatherum gracile Brongn.) has been used and proven empirically to reduce pain, so it may have an analgesic effect. This can be caused by the content of secondary metabolite compounds, flavonoids, tannins, alkaloids, steroids/triterpenoids, saponins and glycosides, but this has not been scientifically proven. This research aims to determine the secondary metabolite compounds contained in fresh bamboo grass herbs, simplicia and dekokta and the effectiveness as an analgesic of the bamboo grass herb dekokta in mice.This research was carried out experimentally, including making simplicia and decoction, phytochemical screening and analgesic effectiveness testing. bamboo grass herb dekokta in male mice induced with 0.5% acetic acid intraperitoneally under the stomach, orally administered bamboo grass herb dekokta at a dose of 100 mg/kgBW, 200 mg/kgBW, 300 mg/kgBW, CMC 0.5% (blank), methampirone 65 mg/kgBB. Count the number of animal movements every 5 minutes for 1 hour. From the number of writhes obtained, the percentage of analgesic power and analgesic effectiveness were calculated. Next, the data obtained was analyzed statistically using SPSS ver.20 One Way ANOVA followed by the Tukey test. The results of the phytochemical screening of fresh bamboo grass, simplicia and dekokta contain alkaloids, flavonoids, tannins, saponins, steroids and glycosides. The greater the dose of bamboo grass herb dekokta given, the greater the percentage of reduction in writhing, so that the analgesic power and analgesic effectiveness are greater. . The results of the One Way ANOVA test and the Tukey test showed that the dose of 300 mg/kgBB had the best analgesic power at 50 minutes, not significantly different from administering 65 mg/kgBB of methampirone.
Pengabdian Kukerta Membangun Desa di Desa Senggoro Kecamatan Bengkalis Kabupaten Bengkalis Taryono Taryono; Septiani Rahayu; Rendy Alfaid; M.Gunawan; Priska Dian Cristina; Adia Pratama Dewi; Nurul Irdina; Muhammad Arsyad Syahputra; Amelia Agustina Putri; Aguslan Aguslan
JPMNT JURNAL PENGABDIAN MASYARAKAT NIAN TANA Vol. 1 No. 4 (2023): Oktober: Jurnal Pengabdian Masyarakat Nian Tana
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/jpmnt.v1i4.116

Abstract

Kukerta Building the Riau University Village in Senggoro Village, Bengkalis District, Bengkalis Regency is a form of community service activity. This Kukerta will be held from 10 July 2023 to 19 August 2023. This kukerta has several themes that can be taken as themes for work programs that will be implemented during the kukerta. These themes are one superior theme and three selected themes. This article discusses work programs that have been successfully implemented during the Kukerta. The method for implementing kukerta that has been implemented consists of carrying out surveys and planning work program activities that are in line with the chosen theme and the conditions and problems that exist in the village. Kukerta student work program activities are in line with existing work programs in the village government and receive support from the village government and also the local community. This is shown by the large number of students who are involved in village and community activities, and vice versa by the large number of students who involve the community and village government in their work program activities. forms of activities involving the village government, namely collaboration activities with the Senggoro village children's forum with go green and leisurely walking activities, mobile legends e-sports tournaments and we also participate in several village activities such as the Clean and Healthy Living Behavior Assessment event which was held in Senggoro Village and the Bengkalis Regent's visit to the Dara Sembilan Tomb on the occasion of the 511th Bengkalis Regency Anniversary. Meanwhile, forms of activities that involve the community include the socialization of several Micro, Small and Medium Enterprises (MSMEs), pious children's festivals, posyandu and mobile legend e-sports tournaments involving many local youth. Riau University Kukerta is expected to provide benefits to village communities and the local village government, especially those aimed at creating significant changes to the village and giving a good impression to the village.