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All Journal Majalah Farmasetika Indonesian Journal of Biological Pharmacy
Bonor, Toga
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Phytochemical Profile Extracts and Fractions of Pisitan Monyet (Dysoxylum caulostachyum Miq.) Bonor, Toga; Among, Sayyid; Febriyanti, Raden Maya; Maisyarah, Intan Timur; Barliana, Melisa Intan
Indonesian Journal of Biological Pharmacy Vol 4, No 1 (2024): IJBP (April)
Publisher : Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijbp.v4i1.55097

Abstract

Dysoxylum is a genus from the Meliaceae family which has 905 species. One species of this genus is Dysoxylum caulostachyum Miq. This species is a plant that has long been consumed as daily food for primates. This plant is starting to be widely researched for its potential for treatment. There are several previous studies showing that D. caulostachyum has antiproliferative, antiplasmodial and anticancer bioactivity. The aim of this paper is to determine the phytochemical profile of D. caulostachyum leaves in the ethanol extract, n-hexane fraction and ethyl acetate fraction of D. caulostachyum leaves. The research was carried out through extraction stages using the maceration method, fractionation using Liquid-Liquid Extraction (ECC), examination of extracts and fractions using Thin Layer Chromatography (TLC), phytochemical screening, and measurement of total phenolic and total flavonoid levels. Based on phytochemical screening, D. caulostachyum leaf extract contains flavonoids, saponins, polyphenols, monoterpenes/sesquiterpenes, quinones, and triterpenes/steroids. The n-Hexane fraction of D. caulostachyum leaves contains quinone compounds, the ethyl acetate fraction of D. caulostachyum leaves contains flavonoids, quinones and polyphenol compounds, while the water fraction of D. caulostachyum contains polyphenol and quinone compounds. From the extract and leaf fractions of D. caulostachyum, data was obtained that the extract contained the highest levels of total phenolics and flavonoids, namely 92.361 ± 1.7245 mg GAE/g and 92.361 ± 1.7245, respectively.
Narrative Review: Analisis Mapping Suhu di Ruang Penyimpanan Pedagang Besar Farmasi (PBF) Bonor, Toga; Ahadi, Husna Muharram; Mulyasyari, Ade Irma; Pratiwi, Rimadani
Majalah Farmasetika Vol 10, No 3 (2025)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v10i2.62328

Abstract

Obat merupakan aspek penting dalam menunjang derajat kesehatan manusia, sehingga memerlukan penjagaan kualitas obat dari hulu ke hilir yang salah satunya penyimpanan. Ruang penyimpanan perlu dilakukannya pemantauan untuk menjaga kualitas dari obat yang disimpan. Kajian literatur ini membahas mapping suhu yang dilakukan pada ruang penyimpanan berbagai PBF (Pedagang besar Farmasi) di kota Bandung dan Jakarta. Metode tinjauan literatur menggunakan narrative review. Artikel yang dicari menggunakan basis data Google Scholar dan Pubmed serta dibatasi terkait dengan tahun terbit dari tahun 2015-2025. Dari hasil review artikel yang dilakukan terdapat beberapa faktor yang menyebabkan fluktuasi suhu yang menjadi faktor penting dalam ruang penyimpanan seperti posisi barang, jumlah barang, posisi ruangan, kuantitas cahaya masuk, dan kelembaban. Posisi dan jumlah barang berperan pada kepadatan ruangan yang berpengaruh pada kelembaban dan sirkulasi udara. Posisi ruangan berperan pada jumlah alat yang digunakan untuk mengontrol suhu. Kuantitas cahaya masuk berperan pada tingkat kelembaban ruangan. Semua faktor tersebut saling mendukung untuk mendapatkan ruangan dengan suhu dengan nilai fluktuatif yang cenderung kecil.
Co-Authors Ahadi, Husna Muharram Among, Sayyid Maisyarah, Intan Timur Melisa Intan Barliana, Melisa Intan Mulyasyari, Ade Irma Raden Maya Febriyanti Rimadani Pratiwi