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All Journal Jurnal Ilmiah Biologi UMA (JIBIOMA) Jurnal Cahaya Mandalika Journal of Natural Sciences Prosiding Seminar Nasional PPG Universitas Mulawarman
Suharsih, Suharsih
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Languange, Linguistic, Communication & Media Other

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Analisis Kadar Kreatinin pada Laki-Laki Pecandu Kopi di Dusun IV Desa Saentis Qibetya, Ananda Nurul; Suharsih, Suharsih; Parinduri, Junaidi; Tamara, Chatrine Virginia
Journal of Natural Sciences Vol 6, No 1 (2025): Journal of Natural Sciences Maret
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v6i1.804

Abstract

Coffee consumption has become a part of people's lifestyles, especially among men. The main component of coffee is caffeine, which has a stimulating effect on the central nervous system. However, excessive consumption can lead to kidney function disorders, which can be identified through increased serum creatinine levels. This study aims to describe creatinine levels in male coffee addicts in Dusun IV, Saentis Village, Percut Sei Tuan District. This research employs a descriptive observational method with a cross-sectional approach. A total of 25 male coffee addicts had their serum creatinine levels measured using the enzymatic method with the Indiko Plus Analyzer. The results showed that the average creatinine level was 1.72 g/dL, with the lowest at 0.77 g/dL and the highest at 2.01 mg/dL. A total of 28% of respondents had high creatinine levels, while 72% were within the normal range. Respondents aged ≥35 years tended to have higher creatinine levels compared to those under 35 years old. Coffee consumption of ≥5 cups per day was associated with increased creatinine levels. This study indicates that excessive coffee consumption may pose a risk to kidney health.
Analisis Perbedaan Kadar Ureum dan Kreatinin dalam Serum dan Plasma pada Pasien dengan Gagal Ginjal di RSU Indah Bagan Batu Rozi, Sihab Fahrul; Suharsih, Suharsih; Febriantika, Febriantika; Parinduri, Junaidi
Journal of Natural Sciences Vol 6, No 1 (2025): Journal of Natural Sciences Maret
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v6i1.806

Abstract

Urea and creatinine serve as key indicators in the evaluation of kidney function. Measurement of urea and creatinine levels can be performed using either serum or plasma. This study aims to compare the results of urea and creatinine level examinations obtained from serum and plasma in patients with kidney failure at RSU Indah Bagan Batu. The research method used is descriptive observational with a cross-sectional approach. The study sample consisted of 22 kidney failure patients who underwent urea and creatinine level examinations using an enzymatic method with an automatic analyzer. The results showed that the average urea level in serum was 186.7 mg/dL, while in plasma, it was 184.9 mg/dL, with a p-value of 0.917 (p 0.05), indicating no significant difference. Similarly, the average creatinine level in serum was 14.17 mg/dL, while in plasma, it was 14.15 mg/dL, with a p-value of 0.988 (p 0.05). Based on these findings, it can be concluded that urea and creatinine level examinations can be conducted using either serum or plasma without significant differences in the results.
Pengaruh Ekstrak Buah Pare (Momordica charantia L.) Terhadap Struktur Mikroskopis Hati Mencit (Mus musculus) Suharsih, Suharsih
Jurnal Ilmiah Biologi UMA (JIBIOMA) Vol 7, No 1 (2025): May 2025
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/jibioma.v7i1.6118

Abstract

Momordica charantia L. (bitter melon) contains various bioactive compounds that may affect internal organs, including the liver. This study aimed to examine the effect of bitter melon fruit extract on the microscopic structure of the liver in mice (Mus musculus). The research was conducted experimentally using a Completely Randomized Design (CRD) without factorial treatment, consisting of five groups: untreated control, aquadest control, and treatment groups receiving bitter melon extract at doses of 750 mg/kg BW, 1500 mg/kg BW, and 2250 mg/kg BW, with five replications each. The extract was administered orally using a gavage needle at a volume of 0.1 mL/10 g BW daily for 40 days. The results showed that the extract did not significantly affect body weight or liver weight. Microscopically, the 750 mg/kg BW and 1500 mg/kg BW doses did not alter liver histology compared to the control, while the 2250 mg/kg BW dose caused histological damage in the form of hepatocyte steatosis. Macroscopically, the liver in the highest dose group appeared paler than in the control group, although the overall shape remained normal in all groups. It can be concluded that high doses of bitter melon extract may induce microscopic liver changes, whereas lower doses do not exhibit hepatotoxic effects.
Uji Efektivitas Jus Buah Naga Merah (Hylocereus polyrhizus) dalam Meningkatkan Hemoglobin pada Karyawan RS Sri Pamela Sabnita, Rara; Suharsih, Suharsih
Journal of Natural Sciences Vol 6, No 2 (2025): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v6i2.684

Abstract

Anemia is a common health issue frequently experienced by individuals in the productive age group, including healthcare workers, and is generally caused by iron deficiency. Red dragon fruit (Hylocereus polyrhizus) is known to contain iron and vitamin C, which may help increase hemoglobin levels. This study aimed to determine the effect of red dragon fruit juice on the hemoglobin levels of employees at Sri Pamela Hospital, Tebing Tinggi. A pre-experimental design with a one-group pretest-posttest approach was used involving 30 respondents (10 males and 20 females) who consumed 200 mL of red dragon fruit juice daily for 10 consecutive days. Hemoglobin levels were measured before and after the intervention using the Drabkin method and an automated hematology analyzer. Statistical analysis using a paired sample t-test showed a significant increase in hemoglobin levels, both in male (14.99 to 16.33 g/dL) and female (13.51 to 15.35 g/dL) participants, with a p-value of 0.000. In conclusion, red dragon fruit juice effectively increases hemoglobin levels and has potential as a natural nutritional intervention for the prevention of mild anemia.
Analisis Penerapan Permainan Go Domino Terhadap Hasil Belajar Pada Mata Pelajaran IPAS Pitaloka Oktaviani, Ananda; Sri Setiani, Siwi; Siddik, Muhammad; Suharsih, Suharsih
Prosiding Seminar Nasional PPG Universitas Mulawarman Vol. 4 (2023): Media Digitalisasi Sebagai Kebutuhan Primer Dalam Pembelajaran Kenormalan Baru
Publisher : Program Studi Pendidikan Profesi Guru, Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/semnasppg.v4.3030

Abstract

Penelitian ini bertujuan untuk menganalisis efektifitas permainan Go Domino terhadap hasil belajar pada mata pelajaran IPAS pada siswa kelas 4 SDN 007 Samarinda Kota. Jenis penelitian ini merupakan penelitian kualitatif dengan teknik pengumpulan data dengan wawancara mendalam (depth interview), observasi dan dokumentasi dengan fokus penelitian mengenai peningkatan hasil belajar peserta didik dalam mata pelajaran IPAS pada materi perubahan wujud benda pada kelas 4 tahun ajaran 2023/2023 di SDN 007 Samarinda. Subjek dari penelitian ini adalah siswa kelas 4 B yang berjumlah 18 orang. Teknik analisis data dilakukan dengan pengumpulan data, mengolah data, penyajian data dan penarikan kesimpulan. Berdasarkan hasil penelitian menunjukkan bahwa permainan Go Domino dapat dijadikan sebagai media pembelajaran alternatif yang efektif yang dapat meningkatkan hasil belajar peserta didik dalam pembelajaran IPAS.
FREKUENSI KASUS GAGAL GINJAL AKUT PADA ANAK YANG DISEBABKAN OBAT-OBATAN SIRUP YANG MENGANDUNG ETILEN GLIKOL PADA TAHUN 2022 Lutfiah, Alya; Pratiwi, Pratiwi; Suharsih, Suharsih; Khairiyah, Syifa; N, Septian Aditiya; A, Tiara Maharani; Frianto, Dedy; Arfania, Maya
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 4 No. 3 (2023)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v4i3.1594

Abstract

In Indonesia, The frequency Acute Kidney Injury (AKI) in children has increase. According KEMENKES’s data until 18 October 2022 frequency Acute Kidney Injury (AKI) in children has increase and potentially caused by used of drugs syrup containing Ethylene Glycol, with deaths of child reaching up to 60% from 206 cases reports from 20 Provinces in Indonesia. Acute Kidney Injury (AKI) is inability kidneys to filtrate compounds inside the body. Generally characterized by cretainin serum has a levels increase in urine, and disability kidney on homoestatis electrolyte and nitrogen. Inside the kidneys, the ethylene glycol compound will be excreted by the enzyme and oxidized into aldehyde glycol and re-oxidated into oxalate acid compounds as a trigger for kidney stones that will damage the kidney.
Co-Authors A, Tiara Maharani Dedy Frianto Febriantika, Febriantika Khairiyah, Syifa Lutfiah, Alya Maya Arfania N, Septian Aditiya Parinduri, Junaidi Pitaloka Oktaviani, Ananda Pratiwi Pratiwi Qibetya, Ananda Nurul Rozi, Sihab Fahrul Sabnita, Rara Siddik, Muhammad Sri Setiani, Siwi Tamara, Chatrine Virginia Wido Supraha