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EFEK PEMBERIAN SEDUHAN SERBUK HERBA SELEDRI (Apium graviolens L.) TERHADAP KADAR ASAM URAT SERUM DARAH AYAM LEGHORN JANTAN HIPERURIKEMIA Kristiyani, Ani
Media Farmasi Indonesia Vol. 16 No. 1 (2021): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.061 KB) | DOI: 10.53359/mfi.v16i1.172

Abstract

Apium graviolens L. is a medicinal plant that is useful for treating gout. Flavonoids are components of chemical compounds found in celery because they can work as antioxidants and inhibit the action of the xanthine oxidase enzyme to form uric acid. This study aims to determine the effect of giving celery herb powder on the blood serum uric acid levels of hyperuricemia male leghorn chickens. This study used twenty-five male leghorn chickens which were randomly divided into 5 groups. All groups were made hyperuricemia by being given 100% chicken liver juice 5 mL/l kg BW once a day orally during treatment. Group 1 was given 0.5% CMC suspension solution as a negative control group. Group 2 was treated with allopurinol 14 mg/1.5 kg BW in CMC 0.5% as a positive control. Groups 3, 4, 5 received infusion of celery herb powder in the order of doses (0.6 g/1.5 kg BW), (1.2 g/1.5 kg BW), (1.8 g/1.5 kg BW). Examination of uric acid levels was carried out on days 0, 4, 8, 12. The results showed that steeping celery could reduce uric acid levels in proportion to the dose. The greater the dose given, the greater the decrease in uric acid levels. The dose of celery herb group 3 (1.8 g/1.5 kg BW) was the most effective doses because it had the same value as the positive control.
Hypertension Drug Sales Pattern in Yogyakarta Through the Tokopedia Platform Piter, Sarah Jesika; Soegiantoro, Didiek Hardiyanto; Kurniawati, Aloysia Yossy; Kristiyani, Ani
Jurnal EduHealth Vol. 16 No. 02 (2025): Jurnal EduHealt, Edition April - June , 2025
Publisher : Sean Institute

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Abstract

Hypertension is a chronic disease with a high prevalence in Indonesia, including the Special Region of Yogyakarta (DIY), so the availability of antihypertensive drugs is crucial. This study aims to examine the sales patterns of antihypertensive drugs through the Tokopedia e-commerce platform in DIY, with a focus on variations in sales volume and types of drugs based on administrative regions and pharmacotherapy classifications. The method used was descriptive quantitative with direct observation on Tokopedia on April 29, 2025, covering five districts/cities: Yogyakarta, Sleman, Bantul, Kulon Progo, and Gunungkidul. The results showed that Sleman Regency recorded 140 boxes and Yogyakarta City recorded the highest sales of 262 boxes, while Bantul recorded 29 boxes and Gunung Kidul 2 boxes while Kulon Progo recorded no sales at all. Generic drugs dominated the sales, especially Calcium Channel Blockers (CCB) with 201 boxes and Angiotensin Receptor Blockers (ARB) with 99 boxes. Meanwhile, branded drugs were mostly found in the ACE Inhibitor group, although in total this group recorded the least number of sales. The conclusions indicate inequality in e-commerce distribution and utilization between districts/cities, as well as public preference for more affordable drugs. Therefore, strategies to equalize access and educate the use of e-commerce in drug distribution are needed, in order to support the equitable and efficient management of hypertension.
Tingkat Pengetahuan Masyarakat terhadap Penggunaan Antibiotik : - Kristiyani, Ani; Patuwo, Syancin
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 2 No. 1 (2024): Bulan Juli 2024 Faskes : Jurnal Farmasi, Kesehatan, dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v2i1.2999

Abstract

Latar belakang: Antibiotik merupakan obat yang digunakan untuk pengobatan infeksi yang disebabkan karena bakteri, namun sering antibiotik digunakan dengan tidak rasional sehingga mengakibatkan terjadinya resistensi terhadap bakteri. Tingkat pengetahuan menjadi salah satu faktor yang mempengaruhi penggunaan antibiotik secara tidak rasional. Tujuan: mengetahui tingkat pengetahuan masyarakat terhadap penggunaan antibiotik melalui review dari beberapa hasil penelitian. Metode: metode review artikel ini adalah dengan pengumpulan data dari jurnal penelitian yang dipublikasi pada rentang tahun 2017-2022 melalui google scohlar dengan kriteria inklusi dan esklusi yang ditentukan Hasil: Hasil penelusuran dari jurnal penelitian sebelumnya diperoleh sejumlah 19 jurnal yang kemudian dilakukan review. Simpulan dan saran: didapatkan kesimpulan tingkat pengetahuan masyarakat terhadap penggunaan antibiotik dengan nilai kurang sejumlah 39,14 %, cukup sejumlah 43,87 %, baik sejumlah 34,15%. Edukasi serta kampanye mengenai antibiotik sangat diperlukan untuk meningkatkan pengetahuan masyarakat sehingga dapat menjadi solusi untuk mencegah terjadinya resistensi 
Penjualan Obat Antidiabetes Kombinasi (Jardiance Duo®) Pada Platform E-Commerce Tokopedia Nata, Ririsiana; Soegiantoro, Didiek Hardiyanto; Kurniawati, Aloysia Yossy; Kristiyani, Ani
Innovative: Journal Of Social Science Research Vol. 5 No. 3 (2025): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v5i3.20011

Abstract

Type 2 diabetes mellitus (T2DM) is a major health problem in Indonesia with increasing prevalence, driven by lifestyle changes and urbanization. The combination of Metformin and Empagliflozin in the Jardiance Duo® product is one of the effective therapies of choice in managing T2DM. Along with the development of e-commerce in the pharmaceutical sector, the Tokopedia platform has begun to provide access to purchase this drug online. This study aims to analyze the effect of selling price and seller's domicile on the sales volume of Jardiance Duo® on Tokopedia. The problems studied include the extent to which selling price influences purchasing decisions and how the geographic distribution of sellers contributes to sales levels. The study used a quantitative-descriptive approach, with data collected through direct observation on the Tokopedia platform on May 23, 2025. The data studied included price, seller location, and sales volume for each Jardiance Duo® variant. The results showed that the selling price in the range of IDR 443,000–IDR 485,000 had the highest sales volume, reflecting high price sensitivity among consumers. The 12.5/500 mg variant was the best-selling, with the highest sales recorded in West Java and East Java. D.I. Yogyakarta recorded no sales at all, indicating an imbalance in geographical distribution. In addition, the uneven pricing between sellers creates uncertainty for consumers regarding the authenticity of the product. The conclusion of this study emphasizes the importance of a competitive pricing strategy and equitable distribution between regions, as well as the need for price regulation and consumer education to increase trust in online drug purchases. These results are expected to be the basis for consideration for digital pharmaceutical industry players and e-commerce platforms in developing more effective distribution and marketing strategies.