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All Journal JURNAL FARMASIMED (JFM) Journal of Community Mental Health and Public Policy MAHESA : Malahayati Health Student Journal El-Mujtama: Jurnal Pengabdian Masyarakat Humantech : Jurnal Ilmiah Multidisiplin Indonesia El-Mujtama: Jurnal Pengabdian Masyarakat
Sinaga, Haryanti
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Religion Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : JURNAL FARMASIMED (JFM)

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Combination Tea of Vernonia Amygdalina Del. Leaves and Syzygium Polyanthum Leaves as Complementary Therapy for Type 2 Diabetes Mellitus Wahyudi, Wahyudi; Sinaga, Haryanti; Tanjung, Hazira Yulistia
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2303

Abstract

Type 2 diabetes mellitus (T2DM) is a global health problem that increase every year. This study aims to test the effectiveness of a combination of African leaf and bay leaf tea as a complementary therapy for type 2 diabetes mellitus (TEDAS). This experimental research used mice induced with alloxan. Treatment and observation of antidiabetic effects were carried out for 12 days of treatment and KGD was measured every 3 days. There were 6 test groups including positive control using glibenclamide, negative control, no treatment, TEDAS1, TEDAS2 and TEDAS3. Phytochemical screening shows that TEDAS contains secondary metabolite compounds including tannins, alkaloids, flavonoids and saponins. The results showed that all TEDAS groups significantly reduced blood glucose levels. KGD examination on day 12 showed that the KGD in the group without treatment was 87, negative control 126 mg/dL, positive control 90 mg/dL, TEDASI 95 mg/dL, TEDAS2 91 mg/dL, and TEDAS3 96 mg/dL. The most effective group is TEDAS2 with glibenclamide + DA 100mg/Kgbb + DS 50mg/Kgbb treatment. Research indicates that TEDAS is effective as a complementary therapy for T2DM.
Co-Authors Despiana, Dwi Fidorova, Yolanda Indah Syahfitri, Rizky Nofi Susanti Putra Apriadi Siregar Rapotan Hasibuan Sekar Zahroh, Diajeng Ayu Syahfitri, Rizky Indah Tanjung, Hazira Yulistia Tumanggor, Suro Rahmadhona Wahyudi Wahyudi Zahroh, Diajeng Ayu Sekar Zata Ismah