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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Detector: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Medical Laboratory Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Romaito Nasution
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Efek Kepuasan Hidup pada Pengobatan Sarcoidosis Milna Sari; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Nurzahara Sihombing; Romaito Nasution
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 4 (2024): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i4.4423

Abstract

This meta-analysis investigated the effect of life satisfaction on Sarcoidosis treatment outcomes across 47 studies encompassing 8,932 patients. The findings revealed a significant positive correlation between life satisfaction and treatment success (r = 0.62, p < 0.001). Patients with high life satisfaction scores (>7.5/10) demonstrated a 73% higher likelihood of achieving remission compared to those with low scores (<5/10) (OR = 2.84, 95% CI: 2.31-3.49). Regression analysis indicated that each one-point increase in life satisfaction scores was associated with an 18% reduction in Sarcoidosis relapse rates (β = -0.18, p = 0.002). Treatment adherence and health behaviors were found to mediate the relationship between life satisfaction and Sarcoidosis treatment outcomes, accounting for 42% and 35% of the variance, respectively. Moderator analyses demonstrated stronger effects among patients with disease duration <5 years (p = 0.011) and those with mild to moderate disease severity (p = 0.003). These findings extend the work of Lee et al. (2020) and Martínez-García et al. (2021) by demonstrating a more pronounced effect of life satisfaction on Sarcoidosis treatment compared to other chronic conditions. Notably, contrary to Saketkoo et al (2021) previous study, the effect of life satisfaction remained significant even after controlling for patients' socioeconomic factors (β = 0.41, p < 0.001). These results underscore the crucial role of psychosocial interventions in enhancing Sarcoidosis treatment efficacy, offering new perspectives in the management of this chronic condition.
Hubungan Dukungan Sosial dalam Pengobatan Sklerosis Multipel Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Nurzahara Sihombing; Romaito Nasution; Milna Sari
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 4 (2024): November : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i4.4424

Abstract

This meta-analysis examined the relationship between social support and medication adherence among multiple sclerosis (MS) patients through a synthesis of 47 studies (N=12,356). The findings confirmed a significant positive correlation (r=0.42, p<0.001, 95% CI [0.38, 0.46]) with substantial heterogeneity (I²=84.0%). Contrary to Cohen et al.'s (2019) finding that informational support was the strongest predictor, our moderator analyses revealed emotional support as the most robust predictor (β=0.39, p<0.001). Furthermore, this research demonstrated that the effects of social support on MS medication adherence were stronger among women (β=0.18, p=0.023) and patients with longer disease duration (β=0.24, p=0.009), extending Franqueiro et al.'s (2023) findings regarding gender differences in social support effectiveness. Family support showed the largest effect (r=0.48, p<0.001), followed by friends (r=0.40, p<0.001) and healthcare providers (r=0.35, p<0.001). Moreover, mediation modeling revealed a significant role of self-efficacy (indirect effect=0.21, 95% CI [0.17, 0.25]), expanding upon Bandura's (2018) model. Supporting Lavorgna et al.'s (2018) findings, our results confirmed that online social support proved equally effective as offline support (Q=1.87, p=0.171). These findings demonstrated robustness through sensitivity analyses and trim-and-fill procedures, confirming resilience against publication bias (adjusted r=0.39, 95% CI [0.35, 0.43]). The novelty of this research lies in its comprehensive identification of key moderators and underlying mechanisms in the social support-medication adherence relationship and the first empirical testing of an integrated mediation model incorporating social support, self-efficacy, and medication adherence in the MS context.
The Psychological Construct of Islamic Moderation Based on Tafsir Ulul Albab : A Comparative Study of Indonesia and Syria in Responding to Social Polarization Nurzahara Sihombing; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Romaito Nasution; Milna Sari
Medical Laboratory Journal Vol. 3 No. 3 (2025): September : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i3.792

Abstract

This study aims to affirm the construct validity of Islamic moderation based on the tafsir of Ulul Albab through an empirical comparison between Indonesia and Syria in responding to the social polarization that divides contemporary societies. Through a comprehensive meta-analysis of 847 journal articles indexed in Scopus, Web of Science, and PsycINFO published between 2015 and 2024, the researchers examined data from 15,428 Indonesian respondents and 12,736 Syrian respondents, integrating cross-cultural quantitative findings within a rigorous statistical framework. The results of the confirmatory factor analysis demonstrated model fit (χ²/df = 2.184; CFI = 0.947; TLI = 0.932; RMSEA = 0.041), while convergent validity indicated an AVE of 0.563 in Indonesia and 0.589 in Syria, with composite reliability values of 0.891 and 0.876 respectively, underscoring the internal consistency of the instrument. Cross-national invariance testing revealed statistically significant differences (Δχ² = 47.23; p < 0.001), with the mean score of Islamic moderation in Indonesia (M = 4.12; SD = 0.67) surpassing that of Syria (M = 3.84; SD = 0.78), indicating that distinctive sociohistorical contexts influence the implementation of moderative values. Furthermore, Islamic moderation functioned as a partial mediator of the relationship between religious literacy and social tolerance (β = 0.342; p < 0.001 for Indonesia; β = 0.287; p < 0.001 for Syria), thereby enriching Pargament's (2011) findings on religious coping and Durrheim et al.'s (2016) work on intergroup prejudice. The findings reveal that Islamic moderation encompasses cognitive, affective, and behavioral dimensions that are theoretically distinct from generic notions of tolerance, affirming the importance of the Ulul Albab approach in addressing socio-religious tensions. Lastly, the novelty of this research lies in the development of a tailored instrument that synthesizes values derived from the tafsir of Ulul Albab, going beyond conventional tolerance scales and offering a more nuanced assessment of the moderative capacity of Muslims in both countries.
Peran Harapan dalam Kepatuhan Pengobatan Kanker Kolorektal M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawa; Romaito Nasution; Milna Sari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.793

Abstract

This meta-analysis investigates the relationship between hope and medication adherence in colorectal cancer (CRC) patients. Out of 1,247 identified articles, 18 studies met the inclusion criteria, encompassing 3,562 patients. The findings reveal a significant positive correlation between hope and medication adherence (r = 0.42, 95% CI: 0.35-0.49, p < 0.001), with notable heterogeneity (I² = 76.4%, Q = 72.03, df = 17, p < 0.001). Furthermore, subgroup analyses indicate a stronger effect in patients with advanced-stage cancer (r = 0.49, 95% CI: 0.39-0.58) compared to those in various earlier stages (r = 0.38, 95% CI: 0.30-0.46, Q = 4.12, df = 1, p = 0.04). No significant differences were found regarding the influence of hope on medication adherence based on treatment type or the country of the study. Additionally, this research extends the findings of DiMatteo et al. (2000) concerning the impact of depression on medication nonadherence, emphasizing the importance of positive psychological states. Moreover, the larger effect size observed for self-efficacy and adherence (r = 0.31) reported by Hall et al. (2016) underscores the relative significance of hope in CRC medication adherence. The novelty of this research lies in its comprehensive synthesis of the hope-adherence relationship within the CRC context, clarifying the varied and partial findings of Zhu et al. (2017) and García-Torres et al. (2016). Consequently, these results support the development of hope-based interventions to enhance medication adherence, as Snyder (2002) suggested in the specific context of CRC. Future research should focus on longitudinal analyses and intervention trials to clarify causal relationships and the effectiveness of hope-based approaches in improving CRC medication adherence.
Co-Authors Helsa Nasution Ika Sandra Dewi Luthfiah Mawa Luthfiah Mawar M. Agung Rahmadi Milna Sari Nurzahara Sihombing