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All Journal MOTORIK Medimuh : Jurnal Kesehatan Muhammadiyah Medical Sains : Jurnal Ilmiah Kefarmasian
Ayu Mulyani
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Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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TINGKAT KETAHANAN DIRI TERHADAP PENYALAHGUNAAN NARKOBA PADA MAHASISWA PRODI S1 STF MUHAMMADIYAH CIREBON DENGAN ANTI DRUG SCALE Rahmi Nurhaini; Tomi; Sidik Lingga Kusuma; Yuniarti Falya; Dahlia Nur Rahmawati; Ayu Mulyani
MOTORIK Jurnal Ilmu Kesehatan Vol 19 No 2 (2024): September
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/motorik.v19i2.1137

Abstract

Drug abuse is the act of using drugs without rights or against the law. Drug abuse can be caused by internal or external factors within a person. This research aims to see a picture of a person's level of resistance to drug abuse among students of the STF Muhammadiyah Cirebon undergraduate study program. In this research, a prospective observational study was carried out using the ADS (Anti-Drug Scale) questionnaire which was validated in Google form on 95 level II undergraduate study program students as respondents. The results of this research show that the number of female respondents is greater than male, namely 81.05%. Most respondents were 20 years old, namely 57.89%. The values for the three ADS dimensions (Anti-Drug Scale) obtained from the questionnaire results showed a percentage of 41.20% in the healthy dimension, 71.84% in the conscious dimension, and 57.37% in the productive dimension. With an average value of self-resilience (anti-drugs) in the three dimensions of 56.80%. So undergraduate study program students have a very high level of self-resilience which can mean that STF Muhammadiyah Cirebon undergraduate study program students have good abilities so they can avoid the effects of drug abuse. Keywords: Drugs; Personal Resilience; STF Muhammadiyah Cirebon student
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI FACE MIST EKSTRAK NADES KULIT BAWANG MERAH (Allium cepa L.) TEHADAP BAKTERI Propionibacterium acnes: FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI FACE MIST EKSTRAK NADES KULIT BAWANG MERAH (Allium cepa L.) TEHADAP BAKTERI Propionibacterium acnes Yayan Rizikiyan; Farhan Zulfa Madani; Ine Suharyani; Sulistiorini Indriaty; Ani Fatonah; Ayu Mulyani
Medimuh : Jurnal Kesehatan Muhammadiyah Vol 5 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/mh.v5i1.1326

Abstract

Kulit bawang merah (Allium cepa L.) telah lama digunakan sebagai obat tradisional karena mempunyai daya hambat pertumbuhan bakteri jerawat seperti Propionibacterium acnes. Oleh karena itu, kulit bawang merah berpotensi digunakan dalam industri makanan dan farmasi. Penelitian mengenai sediaan face mist dari ekstrak NADES kulit bawang merah belum pernah dilakukan sebelumnya. Penelitian ini dilakukan untuk memformulasikan sediaan face mist dengan bahan aktif ekstrak kulit bawang merah (Allium cepa L.) dengan konsentrasi 3%,6%,9% dan untuk mengetahui aktivitas antibakteri face mist tersebut terhadap bakteri Propionibacterium acnes. Kulit bawang merah (Allium cepa L.) diekstrasi menggunakan metode MAE (Microwave Assisted Extraction) dengan pelarut NADES (Natural Deep Eutectic Solvents) yaitu chaoline chloride dan urea perbandingan rasio molar 1:2 selanjutnya dimasukan kedalam microwave dengan waktu 120 menit suhu 60°C, daya yang digunakan 850 watt. Pengujian daya hambat face mist terhadap bakteri Propionibacterium acnes menggunakan metode sumuran. Adanya daya hambat ditunjukan dengan terbentuknya zona bening di sekitar sumur pada media agar.  Diameter hambat diukur menggunakan jangka sorong. Hasil evaluasi face mist ekstrak NADES kulit bawang merah konsentrasi 3%, 6% dan 9% organoleptis, homogenitas, pH, viskositas, bobot jenis, uji waktu kering semuanya memenuhi persyaratan. Hasil pengujian aktivitas antibakteri dari face mist ekstrak NADES kulit bawang merah konsentrasi 3%, 6% dan 9% masing masing sebesar 5,91mm, 7,20mm, dan 9,60mm, ketiganya dapat dikatakan memiliki daya hambat dalam kategori sedang. Kata kunci: face mist, kulit bawang merah, Propionibacterium acnes, MAE
REVIEW ON PHOTOSENSITIZER POTENTIAL OF NATURAL DYES FOR ANTIMICROBIALS USING PHOTODYNAMIC INACTIVATION Ayu Mulyani; Ika Yuni Astuti; Djalil, Asmiyenti Djaliasrin
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1291

Abstract

Infectious diseases still threaten human life, with incidents continuing to increase every year. The increase in antibiotic resistance in recent years has been one of the causes. This incident triggered research to find alternative antibacterial therapies. One such alternative therapy is Photodynamic Inactivation (PDI). This paper reviews the application of PDI for treating diseases caused by microorganisms, especially dermatitis,  periodontitis, blood transfusions, and foodborne diseases, emphasizing the use of natural dyes as photosensitizers. The source for this article was obtained from several indexed databases, such as the National Center for Biotechnology Information (NCBI), Elsevier, and Google Scholar, from 2002 to 2024. The keywords used included “photodynamic therapy", “photodynamic inactivation (PDI)”, "antimicrobial photodynamic therapy (aPDT)", “laser-activated disinfection”, “photoactive disinfection”, “LED”, “natural photosensitizer”, “curcumin”, “riboflavin”, “hypericin”, “chlorophyll and chlorophyllin. Original (clinical and experimental) studies, case series, case reports, and reviews were also included. Letters to the editor and commentaries are excluded. After reviewing 148 relevant articles, 57 were selected. Full texts were read, and data were extracted and entered into tables. The review demonstrated that natural photosensitizers, such as curcumin, hypericin, riboflavin, and chlorophyll derivatives, have the potential to reduce the number of microorganisms in PDI therapy. Photosensitizers can be obtained from several natural sources. Using the PDI procedure, the ROS produced have been proven to effectively inhibit pathogenic microorganisms and can be widely used to treat diseases caused by microorganisms. Keywords: curcumin, hypericin, riboflavin, chlorophyllin derivatives, PDI, natural dye, antimicrobial.
Co-Authors Ani Fatonah Asmiyenti Djaliasrin Djalil Dahlia Nur Rahmawati Farhan Zulfa Madani Ika Yuni Astuti Rahmi Nurhaini, Rahmi Sidik Lingga Kusuma Suharyani, Ine Sulistiorini Indriaty Tomi Yayan Rizikiyan