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REVIEW ARTIKEL PENGARUH VARIASI KOSOLVEN TERHADAP STABILITAS SIRUP PARACETAMOL Fatimi, Hana Anisa; Manurung, Devi Yanthre Sari; Larasati, Rizky Dwi; Ramadhana, Irma Hazira Awalinda; Putranti, Inneke Nurul Dwi; Kholifatuzzahroh; Shafwa, Mayra
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 1 (2024): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i1.1767

Abstract

The syrup is made with the aim of increasing patient acceptance in taking medicine because it is convenient and practical when consumed. Paracetamol is classified as a drug that is rather difficult to dissolve in water with a water solubility of 1: 70 so that in the formulation of syrups it is necessary to assist the dissolution process with several methods such as cosolvention and the addition of surfactants. This review article aims to analyze the studies that have been conducted related to the effect of cosolvent variations on the stability of paracetamol syrup preparation formulations. Several tests were conducted to evaluate the preparation of paracetamol syrup, namely organoleptic test, content determination test, pH test, viscosity test, and specific gravity test. Data was obtained from relevant literature sources such as Google Scholar, ResearchgateNet and Science direct and obtained 10 journals that met the criteria. The use of different cosolvents in syrup will produce different physical values. Paracetamol syrup with PEG 400 and glycerin cosolvents had greater viscosity than paracetamol syrup with propylene glycol and Ryoto sugar ester cosolvents. Paracetamol syrup with PEG 400 and glycerin cosolvents had a greater specific gravity than paracetamol syrup with propylene glycol cosolvents and Ryoto sugar ester surfactant. Based on the results of a review of 10 journal articles, it appears that the use of different cosolvents in paracetamol syrup preparations can modify the preparation and affect the level of stability of the resulting syrup preparation.
Dragon Fruit Peels Waste as Cosmetic: An Overview Fatimi, Hana Anisa; Ramadhana, Irma Hazira Awalinda; Purnama, Magnifico Fatta
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2464

Abstract

Dragon fruit peels (Hylocereus polyrhizus) have various potential as a base ingredient in eco-friendly cosmetic products. This study focused on evaluating the bioactive properties of dragon fruit peels, finding that the compounds contained therein are more effective in counteracting free radicals than the flesh of the fruit. Data collection techniques were carried out by literature study and digital information search with the target objectives in the form of literature study (literature review) searching for information from relevant literature sources for two week in November - December 2024 by searching >30 references from Google Scholar, ResearchgateNet and Sciencedirect, Sinta, MDPI, Pubmed. As well as, official websites in the range of 2014-2024. Literature study was conducted by identifying problems regarding the content of different formulations. The method was through a qualitative approach, which is descriptive research and tends to use analysis. Dragon fruit peel extract showed significant activity in preventing skin damage caused by UV rays and pollution. This innovation not only provides a solution for agro-industrial waste reduction, but also creates sustainable cosmetic products with high economic value. This waste utilization supports the consumer trend towards products based on natural and environmentally friendly ingredients From this review, dragon fruit peels have a great opportunity to be used as an active ingredient in various types of cosmetic products, such as moisturizers, serums, creams, and face masks, with a positive impact on skin health and the environment.
SINERGIS: Sehat, Inovatif, Ekonomi Berkembang, Ramah Digital dan Harmonis Sebagai Program Penguatan Ekonomi, Kesehatan dan Literasi Di Desa Kebondalem Kidul Ramadhana, Irma Hazira Awalinda; Aqila, Fabyan Rayyan; Purnama, Magnifico Fatta; Herawardhani, Nadia; Arbelinda, Levinahansa; Iswandari, Gustina; Azahra, Siti Azizah; Fauziyah, Farah; Sani, Yumna Faisa; Chayono, Argha Dwi; Hadi, Saptono
Pengabdian Masyarakat Vol. 2 No. 2 (2025): Pengabdian Masyarakat (DIMASY)
Publisher : Jurusan Pendidikan Ilmu Pengetahuan Sosial, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/

Abstract

Kegiatan Kuliah Kerja Nyata (KKN) Tematik UNS tahun 2025 di Desa Kebondalem Kidul, Kecamatan Prambanan, Kabupaten Klaten, mengusung tema SINERGIS yang terdiri dari Sehat, Inovatif, Ekonomi Berkembang, Ramah Digital, dan Harmonis. Urgensi kegiatan ini adalah untuk mengatasi permasalahan yang dihadapi masyarakat desa, yaitu rendahnya literasi digital, keterbatasan inovasi dalam UMKM, dan kurangnya pemahaman mengenai kesehatan mandiri. Tujuan utama dari program ini adalah untuk mengoptimalkan potensi lokal melalui pendidikan dan pemberdayaan masyarakat dalam bidang kesehatan, literasi, inovasi UMKM, serta literasi digital. Metode yang digunakan adalah pendekatan partisipatif dan kolaboratif yang melibatkan mahasiswa, masyarakat, dan pemerintah desa. Kegiatan meliputi pelatihan pembuatan lilin aromaterapi berbahan alami, edukasi tentang DAGUSIBU, penyediaan pojok baca, dan sosialisasi mengenai bahaya phishing dan judi online. Hasil dari kegiatan ini diharapkan mampu memberikan dampak positif dalam peningkatan kualitas hidup dan ketahanan sosial-ekonomi masyarakat Desa Kebondalem Kidul, serta mendorong perubahan yang berkelanjutan dalam pemberdayaan ekonomi dan literasi masyarakat.