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All Journal Jurnal Preventia JSFK (Jurnal Sains Farmasi & Klinis) Generics: Journal of Research in Pharmacy Generics : Journal of Research in Pharmacy
Safarudin, Rudi
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Bivariate Spatial Pattern Based on The Characteristics of Women Smokers in Indonesia Putri, Diana Rohmandani; Safarudin, Rudi; Khokar, Ammad; Tayab, Konain; Kashif, Muhammad Taaha; Astutik, Erni
Preventia : The Indonesian Journal of Public Health Vol 8, No 2 (2023)
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um044v8i22023p22-30

Abstract

The increasing prevalence of smoking among women globally has become a critical public health issue. World Health Organization (WHO) data shows 20 percent of women use tobacco. Women smokers face an increased risk of various diseases. Spatial studies need to be conducted as a basis for planning and providing targeted interventions to reduce the spread of diseases caused by smoking. The study aimed to determine the spatial description of smoking among women in Indonesia. This study analyzed the 2017 IDHS data and used an ecological study design with a descriptive approach and a spatial analysis model. The results are Papua was the province with the highest percentage of women smoking with no education and with the lowest de jure wealth quintile. Provinces using the Internet almost daily were Banten and East Java, and the province with women unemployed in the past 12 months before the survey was North Sulawesi. Based on the results, there are five provinces in Indonesia with a high percentage of smoking among women, assessed by education, internet access, wealth quintile, and non-working women. This study concludes that there is a need to implement smoke-free zones (SFZs), also conduct communication, information, and education (IEC) through mass media.
Review: Perbandingan antara Standard Half-Life (SHL) dan Extended Half-Life (EHL) Replacement Therapy berbasis Real-World Evidence (RWE) Sudirman, Agriawan; Suharjono, Suharjono; Nasir, Ahmad; Safarudin, Rudi
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 No 3 (2022): J Sains Farm Klin 9(3), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.3.221-226.2022

Abstract

Hemophilia is a common hereditary coagulation blood disorder due to the deficiency activity of clotting factors. Hemophilia is divided into two, namely hemophilia A and hemophilia B. Among all treatments, standard half-life (SHL) and extended half-life (EHL) factor replacement products are the most commonly used. This study aimed to review real-world evidence on the comparison of SHL and EHL. A literature search was conducted in PubMed and google scholar published from 2017 to 2021. There were 10 articles that met the criteria. Based on the synthesis results, the total proportion of patients using EHL factor concentrates for both on‐demand and prophylactic factor replacement therapy increased. Recent evidence reveals that EHL may reduce the number of infusions, increase factor trough levels, and substantially decrease the annual bleeding rate. Efficacy-wise, EHLs unquestionably have better performances than SHLs; however, the EHL products seem to be too expensive to be utilized as the primary standard of care for hemophilia. However, the economic aspect of the replacement factor switching still required more in-depth studies.
Opioid Use in Palliative Care: A Qualitative Study and Assessment of Patients’ Quality of Life at Anutapura Hospital, Palu, Indonesia. Safarudin, Rudi; Panto, Fyolla Patricia; Bilal, Aresh; Kusumawati, Afriani; Hardani, Ririn; Kustiowaty, Eny; Irnayanti, Irnayanti
Generics: Journal of Research in Pharmacy Vol 6, No 1 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i1.29592

Abstract

Palliative care, being the state of care dealing with patients with terminal conditions often utilizes opioid analgesics to manage the moderate and severe pain endured by the patients. Despite their powerful painkiller, opioids are notorious for their negative consequences on several aspects of the users’ health. To investigate the knowledge, perceptions, and experiences, as well as the quality of life of patients receiving opioids in palliative care. This study is a descriptive qualitative design with a phenomenological approach. Of the 14 opioid users identified between 2023-2024 in palliative setting, with purposive sampling approach, we recruited 5 (five) eligible patients who were willing to participate in the study. We interviewed the patients using the developed questionnaire, referencing the existing published opioid qualitative literature. The eight qualitative questionnaire domains were: (1) Pain/physical ailments (2) Resources/Support system, (3) Knowledge and Awareness of The Medication, (4) Functionality, Autonomy, and Mobility, (5) Physical, Emotional, and Psychological health, (6) Coping/Resources, (7) Feeling of security in treatment, (8) Hope. Furthermore, we added patients’ clinical data from the medical records, and quality of life measured with the SF-12 questionnaire. It is worth noticing that the patients perceived inadequate information about the holistic aspects of opioid use. Regardless, the patients still found that the opioids were viable for their pain management. However, they were still somehow worried about the side effects of the drugs. In general, judging from the SF-12 measurement, the patients had good health conditions. Despite the viability of the drugs in pain management, participants' knowledge of opioids as strong analgesics could still be improved. The opioid users were also still concerned about addiction, physical dependence, and other side effects. Overall, the patients felt the opioids’ benefits, as shown by their relatively good health conditions and quality of life.
Opioid Use in Palliative Care: A Qualitative Study and Assessment of Patients’ Quality of Life at Anutapura Hospital, Palu, Indonesia. Safarudin, Rudi; Panto, Fyolla Patricia; Bilal, Aresh; Kusumawati, Afriani; Hardani, Ririn; Kustiowaty, Eny; Irnayanti, Irnayanti
Generics: Journal of Research in Pharmacy Vol 6, No 1 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i1.29592

Abstract

Palliative care, being the state of care dealing with patients with terminal conditions often utilizes opioid analgesics to manage the moderate and severe pain endured by the patients. Despite their powerful painkiller, opioids are notorious for their negative consequences on several aspects of the users’ health. To investigate the knowledge, perceptions, and experiences, as well as the quality of life of patients receiving opioids in palliative care. This study is a descriptive qualitative design with a phenomenological approach. Of the 14 opioid users identified between 2023-2024 in palliative setting, with purposive sampling approach, we recruited 5 (five) eligible patients who were willing to participate in the study. We interviewed the patients using the developed questionnaire, referencing the existing published opioid qualitative literature. The eight qualitative questionnaire domains were: (1) Pain/physical ailments (2) Resources/Support system, (3) Knowledge and Awareness of The Medication, (4) Functionality, Autonomy, and Mobility, (5) Physical, Emotional, and Psychological health, (6) Coping/Resources, (7) Feeling of security in treatment, (8) Hope. Furthermore, we added patients’ clinical data from the medical records, and quality of life measured with the SF-12 questionnaire. It is worth noticing that the patients perceived inadequate information about the holistic aspects of opioid use. Regardless, the patients still found that the opioids were viable for their pain management. However, they were still somehow worried about the side effects of the drugs. In general, judging from the SF-12 measurement, the patients had good health conditions. Despite the viability of the drugs in pain management, participants' knowledge of opioids as strong analgesics could still be improved. The opioid users were also still concerned about addiction, physical dependence, and other side effects. Overall, the patients felt the opioids’ benefits, as shown by their relatively good health conditions and quality of life.
Co-Authors afriani kusumawati, afriani Astutik, Erni Bilal, Aresh Hardani, Ririn Irnayanti, Irnayanti Kashif, Muhammad Taaha Khokar, Ammad Kustiowaty, Eny Nasir, Ahmad Panto, Fyolla Patricia Putri, Diana Rohmandani Sudirman, Agriawan Suharjono, Suharjono Tayab, Konain