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All Journal Narra J Jurnal Forensik dan Medikolegal Indonesia
Liliana, Belinda
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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PATTERNS OF INJURIES AND PSYCHOLOGICAL TRAUMA IN DOMESTIC VIOLENCE PATIENTS: A SYSTEMATIC LITERATURE REVIEW Gizela, Beta Ahlam; Liliana, Belinda
Jurnal Forensik dan Medikolegal Indonesia Vol 5 No 1 (2024): Jurnal Forensik dan Medikolegal Indonesia
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jfmi.2024.5.1.4817

Abstract

Background: Domestic violence is a complex problem that occurs in various countries in the world. It is noted that women are more often being victims of domestic violence, 1 of 4 women and 1 of 9 men in the world experiencing domestic violence. The number of cases tends to increase from year to year. Domestic violence is bad for the health of victims, both physically and psychologically. Doctors need certain methods to identify domestic violence, include pattern of injuries and psychological trauma of the victims that can be found through physical and mental examination. Aim: To describe the pattern of injuries and psychological trauma experienced by domestic violence patients, and to find corelation between demographic factors of age, gender, and race to the pattern of injuries and psychological trauma. Method: The study is a systematic literature review by analysing literature obtained from databases with specific criteria and keywords about patterns of injuries and psychological trauma in domestic violence patients as well as their association with demographic factors of age, gender, and race. Researchers will explore information from the literature found through the processes of abstraction, analysis, and data synthesis. Result: Based on searches of four electronic databases PubMed, Scopus, ScienceDirect, and EBSCOHost, 241 journals were obtained. After screening through the title, abstract, and exclusive journal, obtained 11 journals. Based on the 11 journals, results were obtained in the form of wound patterns, which include the number, location, and type of wounds; psychological trauma; as well as the corelation of demographic factors, which include age, gender, and race, to pattern of injuries and psychological trauma in domestic violence patients. Conclusion: The location of the most common injuries in domestic violence patients is the head, neck, and face. The most common type of injury found in domestic violence patients is bruising with most experiencing a greater number of injuries. The most common psychological trauma experienced by domestic patients is depression and PTSD. Racial differences had no effect on differences in wound patterns. But in the pattern of psychological trauma, Caucasians have higher rates of PTSD and depression than African-Americans.
Long non-coding RNAs as prognostic biomarkers in non-muscle invasive bladder cancer: A systematic review Hendri, Ahmad Z.; Suryawati, Sri; Heriyanto, Didik S.; Hardianti, Mardiah S.; Pikatan, Narpati W.; Shaleh, Sabillal; Robert, Robert; Febriyanto, Toni; Liliana, Belinda; Pratama, Angga DM.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1233

Abstract

Traditional prognostic tools for non-muscle invasive bladder cancer (NMIBC) often overestimate progression and recurrence risks, underscoring the need for more precise biomarkers. While long non-coding ribonucleic acids (lncRNAs) have been reviewed in bladder cancer, no review has focused on NMIBC. The aim of this study was to address this gap by investigating the role of lncRNAs in predicting NMIBC survival and progression. A systematic review was conducted using PubMed, Scopus, and Cochrane databases as of July 31, 2024. Prognostic studies investigating the association between lncRNA expression and survival outcomes, such as cancer-specific survival, disease-free survival, recurrence-free survival, or overall survival, using Kaplan-Meier curves or hazard ratios, were included. A total of three studies were analyzed, involving 279 NMIBC patients and focusing on three lncRNAs: urothelial cancer associated 1 (UCA1), growth arrest-specific 5 (GAS5), and up-regulated in non-muscle invasive bladder cancer (UNMIBC). Increased UCA1 expression was strongly associated with poor disease-free survival (hazard ratio (HR): 1.974; 95%CI: 1.061–3.673; p=0.032) and progression-free survival (HR: 3.476; 95%CI: 1.187–10.18; p=0.023). Reduced GAS5 expression was significantly associated with poor disease-free survival (HR: 2.659; 95%CI: 1.348–5.576; p=0.005) and progression-free survival (HR: 6.628; 95%CI: 1.494–29.40; p=0.013). Higher level of UNMIBC was strongly associated with poor recurrence-free survival (HR: 2.362; 95%CI: 1.504–4.837; p=0.007). In conclusion, lncRNAs have potential as prognostic biomarkers in NMIBC, with UCA1 and UNMIBC overexpression and GAS5 underexpression being significant in predicting disease recurrence and progression, highlighting the clinical relevance of monitoring these lncRNAs to improve prognosis and guide treatment decisions.
Association of MPV, NLR, PLR and CRP on testicular salvage in testicular torsion: A systematic review and meta-analysis Brodjonegoro, Sakti R.; Rizal, Dicky M.; Arfian, Nur; Luzman, Raedi A.; Pikatan, Narpati W.; Robert, Robert; Febriyanto, Toni; Liliana, Belinda; Yogahutama, Noka; Dwiaji, Iqbal W.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1785

Abstract

Testicular torsion, a critical urological emergency caused by twisting of the spermatic cord, poses a risk of ischemia, particularly in children who often struggle to pinpoint symptoms onset. Delay in managing testicular torsion can lead to the need for orchiectomy. The aim of this study was to assess the association between hematologic parameters—mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP)—and testicular salvage in cases of testicular torsion. Four databases (PubMed, Embase (Ovid), Science Direct, and Scopus) were systematically searched for eligible studies published up to November 4, 2024. The primary outcome was testicular salvage. Sensitivity analysis was performed using leave-one-out plot. Subgroup analysis was performed based on age, country, region, duration to orchiopexy and duration to orchiectomy. Heterogeneity was examined using I² statistics, and a random-effect model was applied. Out of 363 studies identified, nine observational studies involving 796 patients were included, with 338 (42.3%) in orchiopexy group. The meta-analysis indicated that MPV value was significantly elevated in orchiectomy group (mean difference (MD): -0.4; 95% confidence interval (95%CI): -0.62–(-0.18); p<0.01), with higher MPV levels associated with an increased likelihood of orchiectomy (odds ratio (OR): 2.12; 95%CI: 1.35–3.33; p<0.01). NLR, PLR, and CRP showed no significant association with testicular salvage, as demonstrated by pooled MD and OR analyses (p>0.05). No significant differences were observed after sensitivity and subgroup analysis (p>0.05). These findings suggest that elevated MPV levels are associated with non-salvageable testis, requiring orchiectomy highlighting its potential utility in clinical evaluation for testicular torsion.
Co-Authors Beta Ahlam Gizela Brodjonegoro, Sakti R. Dicky M. Rizal, Dicky M. Dwiaji, Iqbal W. Febriyanto, Toni Hendri, Ahmad Z. Heriyanto, Didik S. Luzman, Raedi A. Mardiah S. Hardianti Nur Arfian, Nur Pikatan, Narpati W. Pratama, Angga DM. Robert Robert Shaleh, Sabillal Sri Suryawati Yogahutama, Noka